lncRNA HIF1A-AS2: A potential oncogene in human cancers (Review) [0.03%]
长链非编码RNA HIF1A-AS2：在人类癌症中的潜在致癌作用（综述）
Yang Liu,Yunyan Zhang,Cha Chen et al.
Yang Liu et al.
Long non-coding RNAs (lncRNAs) are transcripts that are >200 nucleotides, but with no open reading frame. An increasing number of lncRNAs have been identified following the development of second-generation sequencing technologies, and they ...
Autophagy controls programmed death-ligand 1 expression on cancer cells (Review) [0.03%]
自噬调控癌细胞程序性死亡配体1的表达(综述)
Lijuan Gao,Yongshun Chen
Lijuan Gao
Programmed death-ligand 1 (PD-L1) is a transmembrane protein mainly located on cancer cells, including renal cell carcinoma, breast, colorectal, gastric and non-small cell lung cancer. PD-L1 binds to the PD-1 receptor expressed on T lymphoc...
Variant Philadelphia t(X;9;22)(q22?;q34;q11.2) can be successfully treated with second generation tyrosine kinase inhibitors: A case report and literature review [0.03%]
应用二代酪氨酸激酶抑制剂成功治疗变异费城染色体t(X;9;22)(q22?;q34;q11.2)白血病一例及文献复习
Ana Iglesias,Raluca Oancea,Carmen Cotarelo et al.
Ana Iglesias et al.
Chronic myeloid leukemia (CML) is characterized by the reciprocal translocation between chromosomes 9 and 22: t(9;22)(q34;q11). However, 5-10% of patients with CML have complex variant translocations involving at least a third chromosome; o...
Case Reports
Biomedical reports. 2021 Oct;15(4):83. DOI:10.3892/br.2021.1459 2021
Droplet-based digital PCR for non-invasive prenatal genetic diagnosis of α and β-thalassemia [0.03%]
基于液滴的数字PCR在无创性产前α和β地中海贫血基因诊断中的应用
Kritchakorn Sawakwongpra,Kulvadee Tangmansakulchai,Wasinee Ngonsawan et al.
Kritchakorn Sawakwongpra et al.
Non-invasive prenatal diagnosis (NIPD) of isolated cell-free DNA from maternal plasma has been applied to detect monogenic diseases in the fetus. Droplet digital PCR (ddPCR) is a sensitive and quantitative technique for NIPD. In the present...
Tripterygium wilfordii derivative LLDT-8 targets CD2 in the treatment of rheumatoid arthritis [0.03%]
雷公藤内酯LLDT-8通过作用于CD2治疗类风湿关节炎
Yuan Li,Wufang Qi,Lei Yan et al.
Yuan Li et al.
Rheumatoid arthritis (RA), a chronic inflammatory synovitis systemic disease, can lead to joint deformities, loss of function and even death. The pathogenesis of RA may be related to genetics, infection and/or sex hormones; however, detaile...
Association between polymorphisms of genes involved in the Renin-Angiotensin-Aldosterone System and the adaptive morphological and functional responses to essential hypertension [0.03%]
肾素血管紧张素醛固酮系统相关基因多态性与原发性高血压形态及功能代偿反应的关系研究
Oana Mocan,Dan Rădulescu,Elena Buzdugan et al.
Oana Mocan et al.
Hypertensive cardiac remodeling is illustrated by increased left ventricular (LV) mass index values and/or relative wall thickness (RWT) values >0.42, and functionally by isolated alteration of LV diastole (abnormal relaxation). The aim of ...
Determining the immunohistochemical expression of GLUT1 in renal cell carcinoma using the HSCORE method [0.03%]
应用HSCORE方法检测肾细胞癌中GLUT1的免疫组化表达
Marin Ogorevc,Ante Strikic,Sandra Zekic Tomas
Marin Ogorevc
The aim of the present study was to compare the immunohistochemical expression of glucose transporter 1 (GLUT1) between the most common histological types of renal cell carcinoma (RCC), and to determine whether a correlation between GLUT1 e...
Promoter polymorphism of TNF-α (rs1800629) is associated with ischemic stroke susceptibility in a southern Thai population [0.03%]
TNF-α（rs1800629）启动子多态性与泰国南部人群缺血性卒中易感性的相关性分析
Kornyok Kamdee,Nitirat Panadsako,Onchuma Mueangson et al.
Kornyok Kamdee et al.
Stroke represents the leading cause of disability and mortality amongst the elderly worldwide. Multiple risk factors, including both genetic and non-genetic components, as well as their interactions, are proposed as etiological factors invo...
A comparison of machine learning classifiers for pediatric epilepsy using resting-state functional MRI latency data [0.03%]
基于静息态功能磁共振潜伏期数据的机器学习分类器在儿童癫痫中的比较研究
Ryan D Nguyen,Matthew D Smyth,Liang Zhu et al.
Ryan D Nguyen et al.
Epilepsy affects 1 in 150 children under the age of 10 and is the most common chronic pediatric neurological condition; poor seizure control can irreversibly disrupt normal brain development. The present study compared the ability of differ...
Elevated levels of serum IL-36α in patients with systemic lupus erythematosus [0.03%]
系统性红斑狼疮患者血清IL-36α水平升高
Xue-Rong Wang,Jian-Ping Xiao,De-Guang Wang
Xue-Rong Wang
The present study aimed to investigate the levels of IL-36α and its association with disease activity in patients with systemic lupus erythematosus (SLE). A total of 60 patients with SLE and 29 healthy controls were enrolled in the present...