Correlation between vitamin D and serum brain derived neurotropic factor levels in type 2 diabetes mellitus patients [0.03%]
维生素D与2型糖尿病患者血清脑源性神经营养因子水平之间的相关性研究
Mohammad Alqudah,Mariam Khanfar,Mahmoud A Alfaqih et al.
Mohammad Alqudah et al.
Diabetes Mellitus (DM) currently ranks as the most common endocrine disorder worldwide. Current opinion views DM as a group of heterogeneous metabolic diseases characterized by hyperglycemia triggered by defects in the ability of the body t...
Amlodipine inhibits proliferation, invasion, and colony formation of breast cancer cells [0.03%]
氨氯地平抑制乳腺癌细胞增殖、侵袭和集落形成
Mohammad A Y Alqudah,Raneem Al-Samman,Marwah Azaizeh et al.
Mohammad A Y Alqudah et al.
Calcium channel upregulation has been implicated in cancer cell proliferation and progression including in breast cancer. Fortunately, the function of calcium channels can be manipulated pharmacologically using calcium channel blockers (CCB...
Rapid identification of Gram-negative pathogens from positive blood cultures using MALDI-TOF MS following short-term incubation on solid media [0.03%]
固体培养基短期孵育后使用基质辅助激光解吸电离飞行时间质谱技术对阳性血培养中的革兰氏阴性菌进行快速鉴定
Ioannis K Neonakis,Demetrios A Spandidos
Ioannis K Neonakis
Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) enables the timely and reliable identification of microbes. The rapid identification of Gram-negative bacteria (GNB) in bloodstream infections is of...
Early biomarkers of nephrotoxicity associated with the use of anti-VEGF drugs [0.03%]
与抗VEGF药物使用相关的肾脏毒性早期生物标志物
Natalia Chebotareva,Katerina Grechukhina,Valerie Mcdonnell et al.
Natalia Chebotareva et al.
Anti-angiogenic anticancer drugs that block vascular endothelial growth factor (VEGF) can cause kidney damage. An early assessment of the risk of nephrotoxicity would allow the development of optimal treatment approaches and allow for relat...
Granulysin expression and granulysin-mediated apoptosis in the peripheral blood of osteoarthritis patients [0.03%]
骨关节炎患者外周血中颗粒素的表达及颗粒素介导的细胞凋亡
Vedrana Drvar,Božena Ćurko-Cofek,Ljerka Karleuša et al.
Vedrana Drvar et al.
Osteoarthritis (OA) is a chronic joint disease caused by mechanical damage and metabolic factors that support the development of low-grade inflammation. Increased levels of T helper 1 pro-inflammatory cytokines in the serum of OA patients m...
Foodborne botulism: A brief review of cases transmitted by cheese products (Review) [0.03%]
由奶制品传播的肉毒杆菌食物中毒：病例简评（综述）
Elias Chaidoutis,Dimitrios Keramydas,Petros Papalexis et al.
Elias Chaidoutis et al.
Food safety constitutes a basic priority for public health. Foodborne botulism occurs worldwide; it is an acute paralytic disease caused by the consumption of food containing the botulinum toxin. Growing consumer demand for cheese products ...
Identification of a novel compound heterozygous CYP4V2 variant in a patient with autosomal recessive retinitis pigmentosa [0.03%]
在常染色体隐性视网膜色素变性的患者中鉴定出一种新的CYP4V2复合杂合变异型
Tongdan Zou,Ting Wang,Fangyuan Zhen et al.
Tongdan Zou et al.
Retinitis pigmentosa (RP) belongs to a family of retinal disorders that is characterized by the progressive degeneration of rod and cone photoreceptors. The aim of the present study was to screen for possible disease-causing genetic variant...
Familial Lynch syndrome with early age of onset and confirmed splice site mutation in MSH2: A case report [0.03%]
MSH2错义突变的林奇综合征家系及病例报告
Zornitsa Bogomilova Kamburova,Savelina Lubenova Popovska,Katya Stefanova Kovacheva et al.
Zornitsa Bogomilova Kamburova et al.
Lynch syndrome (LS) is an autosomal dominant cancer syndrome. It can be caused by mutations of several genes, including MLH1, MSH2, MSH6, PMS2, MLH3 and MSH3, which are responsible for DNA mismatch repair, and LS affects 3-5% of patients wi...
Case Reports
Biomedical reports. 2022 May;16(5):39. DOI:10.3892/br.2022.1522 2022
Therapeutic impact and routine application of next-generation sequencing: A single institute study [0.03%]
高通量测序的临床应用及意义——单中心研究
Rocío Hernández-Pacheco Acosta,María Del Carmen Damas Fuentes,Nicolás Gallego Pena et al.
Rocío Hernández-Pacheco Acosta et al.
Genomic sequencing of tumor tissues provides information on actionable gene aberrations that have diagnostic and therapeutic significance and may guide clinical management through the use of targeted therapies. The indications for these tec...
Genetic association between miR-27a and miR-449b polymorphisms and susceptibility to diabetes mellitus [0.03%]
miR-27a和miR-449b基因多态性与糖尿病易感性的遗传关联研究
Youngmi Choi,Seung-Ho Hong
Youngmi Choi
Various mutations in microRNAs (miRs) are associated with the pathogenesis of several diseases including cancers and vascular diseases. The present study aimed to investigate the potential association between miR-27a A>G (rs895819) and miR-...