Wentao Liu,Yuxin Xu,Shengbin Bai et al.
Wentao Liu et al.
Bladder cancer (BC) is one of the most prevalent genitourinary cancers. Despite the growing research interest in BC, the molecular mechanisms underlying its carcinogenesis remain poorly understood. The microarray datasets GSE38264 and GSE61...
Introduction of new alternative pipeline using multiplexed fast COLD‑PCR together with sequencing approach highlighting pharmacoeconomics by detection of CYP variants [0.03%]
介绍一种新的替代管道，结合多路复用快速COLD-PCR与测序方法，通过检测CYP变体突出药理经济学
Yu Myat Nandar,Suwit Duangmano,Aroonrut Lucksiri et al.
Yu Myat Nandar et al.
In precision medicine, multiple factors are involved in clinical decision-making because of ethnic and racial genetic diversity, family history and other health factors. Although advanced techniques have evolved, there is still an economic ...
Factors associated with disease severity of COVID‑19 in patients with type 2 diabetes mellitus [0.03%]
2型糖尿病患者中COVID-19疾病严重程度相关的因素
Hermina Novida,Soebagijo Adi Soelistyo,Cupuwatie Cahyani et al.
Hermina Novida et al.
Diabetes mellitus causes a decline in immunological function, an increase in proinflammatory cytokines, and a prothrombotic state, thus providing risk factors for the severity of coronavirus disease 2019 (COVID-19) in patients with type 2 d...
Two weeks of high glucose intake is enough to induce intestinal mucosal damage and disturb the balance of the gut microbiota of rats [0.03%]
两周的高葡萄糖摄入足以引起大鼠的肠道黏膜损伤并扰乱其肠道微生物群的平衡
Cunyun Min,Tingting Fu,Wei Tan et al.
Cunyun Min et al.
High glucose plays a critical role in diabetes. However, the point when high glucose induces diabetes and the organ that triggers the initiation of diabetes remain to be elucidated. The aim of the present study was to clarify the damage ind...
Evaluation of human β‑defensins in the cerebrospinal fluid of suspected meningitis [0.03%]
疑似脑膜炎患者脑脊液中人β-防御素的评价
Lena K Jaleel,Mahfoodha A Umran,Khansaa B J Kaddo et al.
Lena K Jaleel et al.
Human β-defensins (HBDs) are an important class of antimicrobial peptides that have immunomodulatory functions; however, the role of HBDs have not been well explored in the pathogenesis of meningitis. A cross-sectional study was performed ...
Analysis of pharmacological interventions among hospitalised patients with COVID‑19: A focus on severe cases [0.03%]
COVID-19住院患者的药物干预分析：重点关注重症病例
Yasutaka Shinoda,Kengo Ohashi,Tomoko Matsuoka et al.
Yasutaka Shinoda et al.
Existing recommendations regarding pharmaceutical interventions for patients with coronavirus disease 2019 (COVID-19) focus on outpatient, inpatient and post-discharge care. However, there are no studies examining the actual activities of p...
Case Reports
Biomedical reports. 2022 Dec 6;18(2):11. DOI:10.3892/br.2022.1593 2022
Sardar Ali Khan,Waqas Shafiq,Umal Azmat et al.
Sardar Ali Khan et al.
Pituitary adenomas are one of the most common benign intracranial tumors, which are normally treated with surgery along with radiation therapy and medication such as dopamine agonist in prolactinoma. The aim of the present study was to eval...
Anastasia Marina Palaiogeorgou,Eleni Papakonstantinou,Rebecca Golfinopoulou et al.
Anastasia Marina Palaiogeorgou et al.
Huntington's disease (HD) is a neurodegenerative disorder characterized by severe motor, cognitive and psychiatric symptoms. Patients of all ages can present with a dysfunction of the nervous system, which leads to the progressive loss of m...
Risk factors of left ventricular hypertrophy in obstructive sleep apnea [0.03%]
阻塞性睡眠呼吸暂停中左心室肥厚的危险因素
Sittichai Khamsai,Thanachai Sanlung,Panita Limpawattana et al.
Sittichai Khamsai et al.
Obstructive sleep apnea (OSA) and left ventricular hypertrophy (LVH) are both related to major cardiovascular diseases. Previous studies have indicated that, compared with non-OSA, OSA is related to LVH with an odds ratio (OR) of 1.70 (95% ...
Pioglitazone modulates immune activation and ameliorates inflammation induced by injured renal tubular epithelial cells via PPARγ/miRNA‑124/STAT3 signaling [0.03%]
吡格列酮通过PPARγ/miRNA-124/STAT3信号转导调控免疫激活并减轻受损肾小管上皮细胞诱导的炎症反应
Walaa Bayoumie El Gazzar,Mona Maher Allam,Sherif Ahmed Shaltout et al.
Walaa Bayoumie El Gazzar et al.
Acute kidney injury (AKI) is commonly a result of renal ischemia reperfusion injury (IRI), which produces clinical complications characterized by the rapid deterioration of renal function, leading to chronic kidney disease and increases the...