Syntaxin1A in synaptopathies: From molecular mechanisms to therapeutic implications in neurological disorders (Review) [0.03%]
syntaxin1A在突触疾病中的作用:从分子机制到神经疾病的治疗意义(综述)
Yating Huang,Jun Xi,Baoling Su et al.
Yating Huang et al.
Syntaxin1A (STX1A) is a presynaptic membrane protein that is abundantly expressed in the central nervous system. It is a key member of the soluble N-ethylmaleimide sensitive factor attachment protein receptor protein family. Notably, STX1A ...
Research progress in the role and mechanism of GALNT3 in human diseases (Review) [0.03%]
GALNT3在人类疾病中的作用及机制研究进展(综述)
Linhong Su,Yongxiu Lin,Xiaoxia Hu et al.
Linhong Su et al.
Protein glycosylation is a crucial post-translational modification. Polypeptide N-acetylgalactosaminyltransferase 3 (GALNT3) is a glycosyltransferase that plays an essential role in various human diseases by modifying proteins, including fi...
Pharmacological treatment patterns, factors associated with glycemic control, and renal function parameters in a real-world cohort of Hispanic adults with type 2 diabetes [0.03%]
2型糖尿病Hispanic成年人的药物治疗模式、血糖控制相关因素及肾功能参数的真实世界队列研究
Janet Diaz-Martinez,Carlos Duran,Michelle Hospital et al.
Janet Diaz-Martinez et al.
Type 2 diabetes mellitus (T2DM) disproportionately affects Hispanic populations, yet real-world treatment patterns and factors associated with glycemic control in this group are poorly characterized. Optimal glycemic control is essential to...
Factors associated with respiratory disturbance index higher than apnea-hypopnea index in patients with obstructive sleep apnea [0.03%]
阻塞性睡眠呼吸暂停患者呼吸紊乱指数高于呼吸暂停低通气指数的相关因素分析
Sitta Suntrawanichakul,Watchara Boonsawat,Sittichai Khamsai et al.
Sitta Suntrawanichakul et al.
Polysomnography, used for diagnosing obstructive sleep apnea (OSA), is commonly available with a home sleep apnea test (HSAT) and in-laboratory polysomnography. In-laboratory polysomnography, the gold standard test, is expensive and has a l...
ALDH5A1 as a key in osteonecrosis of the femoral head: Insights from bioinformatics and experimental validation [0.03%]
乙醛脱氢酶5家族成员A1在线粒体中促进股骨头坏死的发病机制:生物信息学和实验分析的新发现
Tianyu Ren,Qingfa Qin,Li Pang et al.
Tianyu Ren et al.
The present study aims to identify key genes and elucidate the molecular mechanisms underlying osteonecrosis of the femoral head (ONFH), with the goal of discovering effective diagnostic and therapeutic targets. Microarray data were sourced...
Mechanisms of monosodium urate crystal-induced bone destruction in gouty arthritis (Review) [0.03%]
尿酸盐晶体诱导痛风性关节炎骨破坏的机制(综述)
Liekui Hu,Huizhen Li,Xin Huang et al.
Liekui Hu et al.
The deformities and disabilities resulting from bone destruction in gouty arthritis impose substantial physical and psychological burdens on patients, underscoring the urgent need to elucidate the mechanisms underlying gout-induced osteolys...
Efficacy and safety of antifungal prophylaxis in surgical intensive care unit patients: A systematic review and meta-analysis of randomized controlled trials [0.03%]
外科重症监护室抗真菌预防的有效性和安全性:随机对照试验的系统评价和荟萃分析
Ika N Kadariswantiningsih,Maulana A Empitu,Edwin Danardono et al.
Ika N Kadariswantiningsih et al.
Invasive fungal infections (IFIs) are serious complications among surgical intensive care unit (ICU) patients, leading to substantial morbidity and mortality. Antifungal prophylaxis and pre-emptive strategies are employed to reduce the risk...
Near-work activity duration and myopia in children: An updated systematic review and meta-analysis [0.03%]
近距离用眼时长与儿童近视关系的系统综述及meta分析
Yanxia Song,Wei Zheng,Xiaoge Yang et al.
Yanxia Song et al.
The present systematic review and meta-analysis aimed to assess the association between near-work activity and myopia in children, as well as to examine the influence of potential moderators, such as age, region and study design. Multiple d...
Nihaal Dinesh,Madhuvan Hithelmane Sreeramaiah,Sai Chakith Matta Ravi et al.
Nihaal Dinesh et al.
Dextrocardia with situs inversus is an uncommon congenital disorder in which the heart and other organs in the chest and abdomen are reversed. Although it rarely causes symptoms, it can be linked to heart or systemic disorders and is challe...
Case Reports
Biomedical reports. 2026 Mar 18;24(5):59. DOI:10.3892/br.2026.2132 2026
Peroxiredoxin 4 suppresses ferroptosis in esophageal squamous cell carcinoma by activating the phosphoinositide 3-kinase signaling pathway [0.03%]
过氧化氢酶4通过激活磷脂酰肌醇3-激酶信号通路抑制食管鳞状细胞癌的铁死亡
Ke Li,Shuning Xu,Hongtao Liu et al.
Ke Li et al.
Peroxiredoxin 4 (PRDX4) has been found to be upregulated and verified to play protective roles against oxidative stress in various tumors. However, its exact function and underlying molecular mechanisms in esophageal squamous cell carcinoma...