Relationship between remission rate of type 2 diabetes and skeletal muscle after laparoscopic sleeve gastrectomy [0.03%]
腹腔镜袖状胃切除术后2型糖尿病缓解率与骨骼肌的关系
Hironobu Takano,Yuma Ebihara,Yuki Oe et al.
Hironobu Takano et al.
Bariatric surgery can contribute to weight loss and the improvement of obesity-related diseases. Laparoscopic sleeve gastrectomy (LSG) is among the most frequently performed procedures worldwide, including in Japan. Skeletal muscle plays an...
Machine learning-based identification of key genes underlying sex differences in hepatocellular carcinoma and targeted drug screening [0.03%]
基于机器学习的肝细胞癌性别差异关键基因识别及药物筛选研究
Zhen Wang,Jinghua Ning,Hongyuan Zhang et al.
Zhen Wang et al.
Hepatocellular carcinoma (HCC) shows a marked predominance in men, yet the molecular basis for this sex disparity remains unclear. The present study leveraged multi-omics data and machine learning algorithms to identify key genes associated...
Protective effects of Perilla frutescens seed oil on cognitive function, oxidative stress and acetylcholinesterase activity in a D-galactose-induced accelerated aging model in rats [0.03%]
紫苏籽油对D-半乳糖加速老化大鼠认知功能、氧化应激和乙酰胆碱酯酶活性的影响
Watcharaporn Preedapirom Jeefoo,Sitthisak Thongrong,Napapan Kangwan et al.
Watcharaporn Preedapirom Jeefoo et al.
Aging-related cognitive decline is closely associated with oxidative stress, cholinergic dysfunction and hippocampal vulnerability. Perilla seed oil (PSO), a functional food rich in α-linolenic acid and antioxidant phytochemicals, may have...
Pentoxifylline in patients with COVID-19 and with liver cirrhosis or metabolic dysfunction-associated steatotic liver disease: Emerging insights [0.03%]
关于COVID-19肝硬化或代谢功能异常相关脂肪肝病患者的 Pentoxifylline：新见解
Miguel Ángel Jiménez-Luevano,Ana Emilia Jiménez-Partida,Miguel Angel Jiménez-Partida et al.
Miguel Ángel Jiménez-Luevano et al.
Coronavirus (CoV) disease 2019 (COVID-19) deteriorates existing hepatopathies, such as liver cirrhosis and metabolic-associated syndrome liver disease (MASLD), which in turn increases the risk of serious complications. The pathophysiology o...
Exosome-like nanoparticles from the Okinawan medicinal plant Talinum fruticosum exhibit subset-specific bioactivities in vitro: Suppression of IL-6 production and reduction of intracellular reactive oxygen species [0.03%]
源于冲绳药用植物半边莲的类外泌体纳米颗粒具有独特的体内生物活性：抑制白介素-6（IL-6）生成及减少细胞内活性氧簇
Yasunari Kageyama,Kazunori Namba,Yuki Akamatsu et al.
Yasunari Kageyama et al.
Plant-derived exosome-like nanoparticles (ELNs) exhibit diverse physiological activities across biological kingdoms. Talinum fruticosum (L.) Juss., known in Okinawa as 'Shibiran', is a traditional edible medicinal plant that is considered a...
Comprehensive clinicopathological evaluation of malignant localized gingival enlargements in the Thai population [0.03%]
泰国人群牙龈恶性局部增生的综合临床病理评估
Dulyapong Rungraungrayabkul,Pawat Sripodok,Tawepong Arayapisit et al.
Dulyapong Rungraungrayabkul et al.
Malignant localized gingival enlargements (LGEs) are rare and often clinically mimic reactive or benign lesions, creating diagnostic challenges. The present study aimed to evaluate the prevalence and origins of malignant LGEs, assess clinic...
Comparative efficacy and safety of remimazolam vs. dexmedetomidine: A systematic review and meta-analysis [0.03%]
remimazolam与dexmedetomidine疗效和安全性的比较：系统评价和.meta.分析
Rong Hu,Rongxiao Ping
Rong Hu
Sedation is a critical component of modern anesthesia and procedural medicine, particularly outside the operating room. Dexmedetomidine and remimazolam have emerged as prominent sedatives due to their unique pharmacological profiles. Howeve...
Prophylactic effects of Acanthopanax senticosus Harms on the development of colitis in mice [0.03%]
刺五加预防小鼠结肠炎的效应研究
Yutaka Kawano,Dai Tsuchida,Hiromichi Furutaka et al.
Yutaka Kawano et al.
Inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis (UC), comprises chronic relapsing inflammatory disorders of the gastrointestinal tract. Although the acute dextran sodium sulfate (DSS)-induced murine c...
Platelet-rich plasma in the management of diabetic foot ulcers (Review) [0.03%]
富血小板血浆在糖尿病足溃疡管理中的应用(综述)
Andrei-Alexandru Tomac,Cătălin Mircea Coșarcă,Cristian Trâmbițaș et al.
Andrei-Alexandru Tomac et al.
Diabetes mellitus represents a major global health concern, frequently complicated by chronic, non-healing wounds such as diabetic foot ulcers (DFUs). These ulcers are a leading cause of morbidity, impaired quality of life and limb amputati...
Subtype-specific associations between serum lipid profiles and disease severity in patients with amyotrophic lateral sclerosis [0.03%]
肌萎缩侧索硬化症患者的血清脂质谱与疾病严重程度的亚型特异性关联分析
Lu Cao,Gang Chen,Jing Zhou et al.
Lu Cao et al.
Amyotrophic lateral sclerosis (ALS) is a heterogeneous neurodegenerative disorder. Notably, the differences in lipid metabolism between bulbar- and limb-onset subtypes of ALS remain unclear, particularly in non-Western populations. The pres...