Clozapine (and norclozapine) concentrations are correlated with functioning, disability and side-effects when patients are treated with clozapine without the availability of therapeutic drug monitoring: A study of treatment-resistant schizophrenia inpatients [0.03%]
无量化的氯氮平血药浓度与治疗抵抗型精神分裂症入院患者的功效、残疾和副作用之间存在相关性：一项横断面研究
Veroljub Petrovic,Dan Cohen,Dragic Bankovic et al.
Veroljub Petrovic et al.
In numerous countries, including Serbia, therapeutic drug monitoring (TDM) for clozapine is unavailable, leaving dose adjustments based solely on clinical judgment, could increase risk of therapeutic failure or adverse outcomes. The present...
Role of the gut microbiota in the pathogenesis and therapeutic approach to osteoporosis (Review) [0.03%]
肠道菌群在骨质疏松症发病机制及治疗中的作用（综述）
Mingyue Ao,Xing Li,Chun Xiao et al.
Mingyue Ao et al.
Osteoporosis (OP) is a chronic systemic metabolic bone disease characterized by an imbalance between bone resorption and bone formation, resulting in a decrease in bone mass and density. Additionally, the deterioration of bone tissue micros...
Ossification in pancreatic neoplasms: A report of three cases of neuroendocrine tumor, mucinous cystic neoplasm, and intraductal papillary mucinous neoplasm with review of the literature [0.03%]
胰腺神经内分泌肿瘤、黏液性囊性肿瘤和导管内乳头状黏液性肿瘤骨化的病例报告及文献复习
Yutaro Fukuma,Mitsuaki Ishida,Emi Yasuda et al.
Yutaro Fukuma et al.
Heterotopic ossification (HO) is the formation of mature bone tissues in non-skeletal tissues and has been reported in various types of neoplasms. The presence of HO in pancreatic tumors is rare, with only 16 cases reported in the English l...
Case Reports
Biomedical reports. 2025 Nov 10;24(1):10. DOI:10.3892/br.2025.2083 2025
Assessment of anionic siRNA lipoplexes prepared via modified ethanol injection for tumor cell delivery [0.03%]
采用改良乙醇注射法制备阴离子siRNA脂质复合物并对其肿瘤细胞递送效果进行评估
Yoshiyuki Hattori,Aya Kurihara,Mizuki Shinkawa
Yoshiyuki Hattori
Our previous study introduced a modified ethanol injection (MEI) method for preparing positively charged small interfering RNA (siRNA) lipoplexes by mixing a lipid-ethanol solution of cationic lipid, 1,2-dioleoyl-sn-glycero-3-phosphoethanol...
Genotypic and hematological profiling of thalassemia in reproductive-age and pediatric populations [0.03%]
生殖年龄和儿科人群的血红蛋白病基因分型及血液学特征分析
Yanhong Liu,Wei Ye,Yan Zhang et al.
Yanhong Liu et al.
Thalassemia is mainly prevalent in southern China, but consistent regional epidemiological data remain scarce in Hubei Province (central China). The present study characterized thalassemia genotypes and hematological parameters in 2,604 non...
Efficacy of oral vs. intravenous iron for the treatment of iron deficiency anemia in different conditions: A systematic review and meta-analysis [0.03%]
口服铁剂与静脉用铁剂在不同条件下治疗缺铁性贫血疗效的系统评价和meta分析
Caifang Zhao,Wei He
Caifang Zhao
The present systematic review and meta-analysis evaluated the efficacy and safety of oral vs. intravenous (IV) iron therapy in managing iron deficiency anemia (IDA) across various clinical conditions. A comprehensive search was conducted in...
Potential of organ-on-a-chip in advancing synthetic extracellular matrix technology for bone tissue engineering in dentistry (Review) [0.03%]
器官芯片在牙科骨组织工程合成细胞外基质技术中的应用前景(综述)
Muhammad Hidayat Syahruddin,Ika Dewi Ana,Dmitry Belyaev et al.
Muhammad Hidayat Syahruddin et al.
Bone tissue engineering (BTE) is a cutting-edge approach within biomedical sciences, especially in regenerative medicine, addressing key challenges such as organ transplantation and complex tissue repair. At the core of BTE is the developme...
Progress in targeted therapy for prostate cancer via cell surface proteins (Review) [0.03%]
基于细胞表面蛋白的前列腺癌靶向治疗研究进展（英文）
Hua Luo
Hua Luo
Prostate cancer (PCa), particularly metastatic castration-resistant PCa, remains a significant therapeutic challenge. Cell-surface proteins have emerged as promising therapeutic targets. The present review examines the biological characteri...
Downregulation of sialyl-transferases and their role in malignant meningioma cells [0.03%]
唾液转移酶的下调及其在恶性脑膜瘤细胞中的作用
Pitchanun Jaturutthaweechot,Phattrara Khuansonthi,Pundit Asavarittikrai et al.
Pitchanun Jaturutthaweechot et al.
Meningiomas are the most common primary intracranial tumors and are often curable with gross resection. However, surgery is not entirely effective, as recurrences are reported more frequently in patients with meningiomas with higher-grade t...
Supplementation of aged garlic extract attenuates age-associated memory impairment and cognitive decline: Involvement of molecular pathways in the cortex and hippocampus [0.03%]
大蒜提取物补充剂可减轻与年龄相关的记忆力减退和认知能力下降：海马区及大脑皮层分子通路的参与作用
Tamanna Mony,Marcus Jackson,Amitai Zuckerman et al.
Tamanna Mony et al.
The aging of the human population is associated with increases in comorbidities, including functional impairment and cognitive decline. With decreasing numbers of neurons and declining synaptic plasticity, the aging brain exhibits less perf...