Analysis of conditioning with dexmedetomidine under endothelial dysfunction in isolated perfused hearts [0.03%]
丁丙宁卡因用于内皮功能障碍条件下分离灌注心脏的预适应效应分析
Sophia De Luca-Rohner,André Heinen,Martin Stroethoff et al.
Sophia De Luca-Rohner et al.
Cardioprotective strategies such as pharmacological conditioning have not yet successfully undergone bench-to-bedside transfer, which is probably due to inhibition of cardioprotection by comorbidities or associated pathological changes. End...
Valproic acid exposure alters histone deacetylase mRNA expression profile in oral cancer and premalignant cell lines [0.03%]
丙戊酸暴露改变口腔癌和癌前细胞系组蛋白去乙酰酶mRNA表达谱型
Ahmed S K Al-Khafaji,Yasir B Qaddoori,Haidar H Alabdei et al.
Ahmed S K Al-Khafaji et al.
The common frequent precursors to head and neck squamous cell carcinoma (HNSCC) are oral dysplasias (ODs). Nonetheless, methods for prediction or prevention of the malignant transformation of OD are unreliable. Therefore, oral HNSCC is ofte...
Intronic hexanucleotide repeat expansion in TYMS in monozygotic twins with congenital progressive universal melanosis [0.03%]
同卵双胞胎先天进行性全身色素沉着症中的TYMS内含子六核苷酸重复序列扩张
Sunisa Kanchanasutthiyakorn,Sakchai Chaiyamahapurk,Siraprapa Tongkobpetch et al.
Sunisa Kanchanasutthiyakorn et al.
Hyperpigmentation presents a diverse clinical spectrum, largely influenced by genetic factors that remain incompletely understood. The present study describes a case of monozygotic twin girls aged 15 years with congenital progressive univer...
ARHGAP36 serves as a diagnostic and therapeutic marker that mediates immune escape and promotes thyroid cancer metastasis [0.03%]
ARHGAP36作为诊断和治疗标志物介导甲状腺癌免疫逃逸并促进转移的功能研究
Liyun Yang,Junzhi Liu,Yuhuan Gao et al.
Liyun Yang et al.
Thyroid cancer (THCA) is a prevalent malignancy of the head and neck region, yet the mechanisms underlying its tumorigenesis and metastasis remain poorly understood. Given that Rho GTPase activating protein 36 (ARHGAP36) has been implicated...
Role of Nigella sativa L. seed (black cumin) in preventing photoaging (Review) [0.03%]
Nigella sativa L.种子（黑胡椒）在预防光老化中的作用（综述）
Annisa Evanti,Teresa Liliana Wargasetia,Julia Windi Gunadi
Annisa Evanti
Photoaging is a group of clinical and pathological manifestations caused by ultraviolet (UV) radiation, characterized by deep wrinkles, rough skin textures, dyspigmentation and disturbance of skin elasticity. UV radiation can cause skin dam...
Effects of pine needle essential oil on melanin synthesis in B16F10 cells and its mechanism [0.03%]
松针油对B16F10黑色素细胞黑色素合成的影响及其机制研究
Suyuan Lü,Bingqing Shang,Guolong Liu et al.
Suyuan Lü et al.
The present study aimed to investigate the melanin synthesis effect of pine needle essential oil (PNEO) extracted using microwave-assisted extraction on α-MSH-induced B16F10 melanoma cells and its molecular mechanism of action. Cell Counti...
Luz Victoria Sánchez-Meza,Ciresthel Bello-Rios,Yazmín Gómez-Gómez et al.
Luz Victoria Sánchez-Meza et al.
Cervical cancer (CC) is a major global health concern, ranking fourth worldwide in mortality, due to its high death rate and strong link to persistent high-risk human papillomavirus infections, which drive cancer progression through cellula...
Exploring the potential of honokiol as a treatment for cardiovascular disease (Review) [0.03%]
姜黄素类似物Honokiol的心血管保护作用及机制研究进展
Yao Zeng,Zishan Li,Xiaolong Lin
Yao Zeng
Cardiovascular diseases (CVDs) remain a leading cause of global mortality. As the burden of these diseases continues to rise, the development of innovative therapeutic agents has become increasingly important. Honokiol, a bioactive compound...
Clinicopathological insights of supratentorial embryonal tumor with medulloblastoma-like histopathology in adulthood: A case report [0.03%]
成人幕上具有髓母细胞瘤类似病理特征的胚胎肿瘤的临床病理见解：病例报告
Yinjiao Wang,Aihong Cao,Peng Du
Yinjiao Wang
Embryonal tumor with medulloblastoma-like histopathology (ETMH) is an embryonic-type malignancy originating from remnants of primitive embryonic cells. It is rarer in adults, especially those over the age of 40. Adult ETMH occurring in the ...
Case Reports
Biomedical reports. 2025 May 26;23(2):125. DOI:10.3892/br.2025.2003 2025
Elevated red blood cell-derived extracellular vesicles under hyperglycemic conditions are associated with CD47 expression and production of intracellular reactive oxygen species [0.03%]
高糖条件下红细胞源性外泌体表达CD47并促进内皮细胞活性氧生成增多
Suriyan Sukati,Warangkana Chunglok,Tiwaporn Naulkaew et al.
Suriyan Sukati et al.
Diabetes mellitus (DM), particularly type 2 DM, is characterized by chronic hyperglycemia, which has notable effects on red blood cells (RBCs), including alterations in membrane integrity, morphology and function. The present study aimed to...