Serotonin inhibits the influx of iron into cells by decreasing the expression of SLC11A2 in Caco-2 cells [0.03%]
五羟色胺通过降低Caco-2细胞中SLC11A2的表达来抑制铁向细胞内的流入
Yuta Sugino,Momoko Ameku,Norika Kawanishi et al.
Yuta Sugino et al.
Iron is an essential trace element for biological functions and its homeostasis is strictly regulated. Intestinal iron absorption primarily occurs in the duodenum, and the iron transporter solute carrier family 11 member 2 (SLC11A2; also kn...
Germ cell immunoprofile and KIT exon 17 mutation guide rectification of seminoma misclassified as epithelioid gastrointestinal stromal tumor: A case report [0.03%]
以生殖细胞免疫谱和KIT基因第11外显子突变检测纠正误诊的精原细胞瘤为上皮样胃肠道间质瘤:病例报告
Xinyi Zhang,Wei Yuan,Lei Ren et al.
Xinyi Zhang et al.
Seminoma, derived from germ cell neoplasia in situ, is the most common testicular germ cell neoplasm. Seminoma exhibits overlapping genetic mutations and immunohistochemical profiles with diverse tumors, substantially complicating diagnosis...
Case Reports
Biomedical reports. 2025 Nov 18;24(1):15. DOI:10.3892/br.2025.2088 2025
Janus kinase/signal transducer and activator of transcription pathway in schizophrenia (Review) [0.03%]
细胞内信号转导异常在精神分裂症发病机制中的作用及分子机制研究进展
Emmanouil Rizos,Christos Theleritis,James N Tsoporis et al.
Emmanouil Rizos et al.
Schizophrenia is a complex mental disorder that affects cognition, emotions and behaviour. Among the signaling pathways that show dysregulation in schizophrenia is the Janus kinase/signal transducer and activator of transcription (JAK/STAT)...
Hemp seed extract as a catalyst for cell proliferation via IGF-1 and growth hormone signaling: Increased natural regenerative potential of muscles [0.03%]
大麻籽提取物通过胰岛素样生长因子和生长激素信号促进细胞增殖:增强肌肉的自然再生潜能
Dong Young Kang,Yunkyeong Kwon,Hyo Tae Kim et al.
Dong Young Kang et al.
Hemp seeds provide a nutritious food source. They contain proteins and essential minerals such as phosphorus, potassium, magnesium, iron and zinc. These nutrients contribute to health benefits, including the support of cardiovascular health...
Clozapine (and norclozapine) concentrations are correlated with functioning, disability and side-effects when patients are treated with clozapine without the availability of therapeutic drug monitoring: A study of treatment-resistant schizophrenia inpatients [0.03%]
无量化的氯氮平血药浓度与治疗抵抗型精神分裂症入院患者的功效、残疾和副作用之间存在相关性:一项横断面研究
Veroljub Petrovic,Dan Cohen,Dragic Bankovic et al.
Veroljub Petrovic et al.
In numerous countries, including Serbia, therapeutic drug monitoring (TDM) for clozapine is unavailable, leaving dose adjustments based solely on clinical judgment, could increase risk of therapeutic failure or adverse outcomes. The present...
Role of the gut microbiota in the pathogenesis and therapeutic approach to osteoporosis (Review) [0.03%]
肠道菌群在骨质疏松症发病机制及治疗中的作用(综述)
Mingyue Ao,Xing Li,Chun Xiao et al.
Mingyue Ao et al.
Osteoporosis (OP) is a chronic systemic metabolic bone disease characterized by an imbalance between bone resorption and bone formation, resulting in a decrease in bone mass and density. Additionally, the deterioration of bone tissue micros...
Ossification in pancreatic neoplasms: A report of three cases of neuroendocrine tumor, mucinous cystic neoplasm, and intraductal papillary mucinous neoplasm with review of the literature [0.03%]
胰腺神经内分泌肿瘤、黏液性囊性肿瘤和导管内乳头状黏液性肿瘤骨化的病例报告及文献复习
Yutaro Fukuma,Mitsuaki Ishida,Emi Yasuda et al.
Yutaro Fukuma et al.
Heterotopic ossification (HO) is the formation of mature bone tissues in non-skeletal tissues and has been reported in various types of neoplasms. The presence of HO in pancreatic tumors is rare, with only 16 cases reported in the English l...
Case Reports
Biomedical reports. 2025 Nov 10;24(1):10. DOI:10.3892/br.2025.2083 2025
Assessment of anionic siRNA lipoplexes prepared via modified ethanol injection for tumor cell delivery [0.03%]
采用改良乙醇注射法制备阴离子siRNA脂质复合物并对其肿瘤细胞递送效果进行评估
Yoshiyuki Hattori,Aya Kurihara,Mizuki Shinkawa
Yoshiyuki Hattori
Our previous study introduced a modified ethanol injection (MEI) method for preparing positively charged small interfering RNA (siRNA) lipoplexes by mixing a lipid-ethanol solution of cationic lipid, 1,2-dioleoyl-sn-glycero-3-phosphoethanol...
Genotypic and hematological profiling of thalassemia in reproductive-age and pediatric populations [0.03%]
生殖年龄和儿科人群的血红蛋白病基因分型及血液学特征分析
Yanhong Liu,Wei Ye,Yan Zhang et al.
Yanhong Liu et al.
Thalassemia is mainly prevalent in southern China, but consistent regional epidemiological data remain scarce in Hubei Province (central China). The present study characterized thalassemia genotypes and hematological parameters in 2,604 non...
Efficacy of oral vs. intravenous iron for the treatment of iron deficiency anemia in different conditions: A systematic review and meta-analysis [0.03%]
口服铁剂与静脉用铁剂在不同条件下治疗缺铁性贫血疗效的系统评价和meta分析
Caifang Zhao,Wei He
Caifang Zhao
The present systematic review and meta-analysis evaluated the efficacy and safety of oral vs. intravenous (IV) iron therapy in managing iron deficiency anemia (IDA) across various clinical conditions. A comprehensive search was conducted in...