Fatal dissemination of Strongyloides stercoralis in an HIV-positive patient with preserved immunity: a case report [0.03%]
一例免疫功能正常的艾滋病患者发生巢状肠梗阻性粪类圆线虫病的病例报告
Joel Hurtado Dominguez,Silvana Fernanda Loza Mollinedo
Joel Hurtado Dominguez
We report the case of a 38-year-old woman with human immunodeficiency virus (HIV) infection diagnosed in 2010 and on antiretroviral treatment since 2014, with an undetectable viral load and a CD4 lymphocyte count of 527 cells/µL. The patie...
Research progress of metagenomic next-generation sequencing in infectious diseases of the spine: a systematic review [0.03%]
元基因组下一代测序在脊柱感染性疾病研究中的进展：系统综述
Ziyan Zhu,Xinxin Miao
Ziyan Zhu
Background: Infectious diseases of the spine (IDS) cause structural destruction and abscess formation, requiring precise early diagnosis. While conventional culture methods show limited sensitivity and slow turnaround, me...
Invasive pulmonary aspergillosis in the post-COVID-19 era: diagnosis, treatment, and what lies ahead [0.03%]
新冠肺炎时代侵袭性肺曲霉病的诊断、治疗及展望
Cong Nguyen Hai
Cong Nguyen Hai
Invasive pulmonary aspergillosis (IPA) is a severe opportunistic fungal infection that predominantly affects immunocompromised individuals, including those with hematologic malignancies, organ transplants, and, more recently, patients with ...
Advancing peptide-based vaccines against viral pathogens: a narrative review [0.03%]
基于肽的病毒病原体疫苗的研究进展：叙述性综述
Hamid Reza Jahantigh,Solaleh Rezanavaz Gheshlagh,Ladan Mafakher et al.
Hamid Reza Jahantigh et al.
Peptide-based vaccines, utilizing defined B- and T-cell epitopes, have emerged over the past two decades as promising alternatives to conventional vaccine platforms. Their key advantages, including excellent safety profiles, precise immunol...
A lethal combination: fulminant liver failure due to Babesia microti and Borrelia burgdorferi co-infection [0.03%]
致命的组合：由巴贝斯虫病和莱姆病螺旋体感染引起的一型肝性脑病
Aya Elalfy,Danilo Grahovac,Igor Dumic et al.
Aya Elalfy et al.
Babesiosis and Lyme disease are tick-borne infections endemic to the northeastern and upper Midwestern United States. Although both diseases can involve multiple organ systems, acute liver failure (ALF) is exceedingly uncommon. Co-infection...
Necrotizing gingival infection due to Trichoderma longibrachiatum in an hematopoietic stem cell transplant recipient: case report [0.03%]
造血干细胞移植受者长枝木霉引起的牙龈坏死感染：病例报告
Eduardo Aparicio-Minguijón,Nieves López-Muñoz,Pilar Martínez-Sánchez et al.
Eduardo Aparicio-Minguijón et al.
Trichoderma is a genus of rare filamentous fungi that can cause invasive fungal infections in immunocompromised patients. We report a case of necrotizing gingival and sinus infection due to T. longibrachiatum in an allogeneic stem cell tran...
Towards personalised empirical antibiotic therapy in febrile neutropenia: a theoretical model based on machine learning and prior colonisation with multidrug-resistant gram-negative bacilli - a retrospective proof-of-concept cohort study [0.03%]
基于机器学习和多重耐药革兰阴性杆菌先前定植的发热性中性粒细胞减少症经验性抗生素治疗个体化理论模型的回顾性概念验证队列研究
Antonio Gallardo-Pizarro,Christian Teijón-Lumbreras,Tommaso Francesco Aiello et al.
Antonio Gallardo-Pizarro et al.
Background: Empirical antibiotic therapy (EAT) in febrile neutropenia (FN) remains challenging due to multidrug-resistant (MDR) Gram-negative bacteria, often leading to inappropriate empirical antibiotic therapy (IEAT). ...
Chronic pulmonary aspergillosis complicating pulmonary cystic echinococcosis: a global systematic review [0.03%]
慢性曲霉菌病合并肺棘球蚴病囊肿的全球系统性综述
Felix Bongomin,Aayush Adhikari,Ronald Olum et al.
Felix Bongomin et al.
Background: Human cystic echinococcosis frequently involves the lungs, and colonization of a residual cavity with Aspergillus spores can lead to chronic pulmonary aspergillosis (CPA). ...
Plazomicin in multidrug-resistant complicated urinary tract infections: a scoping review [0.03%]
用于多重耐药复杂性尿路感染的泊玛津：系统综述
Subhash Todi,Rajeev Soman,Yatin Mehta et al.
Subhash Todi et al.
Background: Complicated urinary tract infections (cUTIs) cause significant morbidity and mortality. Multidrug-resistant (MDR) organisms complicate cUTI management, highlighting the need for effective antimicrobials. ...
Imidazolopiperazines as next-generation antimalarial agents: a scoping review of efficacy, mechanisms of action and resistance; prospects for future development [0.03%]
咪唑哌嗪类下一代抗疟药物的疗效、作用机制和耐药性的综述；未来发展的前景
Fatoumata Ousmane Maiga,Laurent Dembele,Mohamed Maiga et al.
Fatoumata Ousmane Maiga et al.
Background: The emergence and spread of antimalarial drug resistance have created an urgent need for novel therapeutic agents. Imidazolopiperazines (IZPs) represent a promising new class of compounds with broad activity a...