Chlamydial infection of the gastrointestinal tract: a reservoir for persistent infection [0.03%]
沙眼衣原体的胃肠道感染：持续性感染的储存库
Laxmi Yeruva,Nicole Spencer,Anne K Bowlin et al.
Laxmi Yeruva et al.
The mechanism by which chlamydiae persist in vivo remains undefined; however, chlamydiae in most animals persist in the gastrointestinal tract (GI) and are transmitted via the fecal-oral route. Oral infection of mice with Chlamydia muridaru...
Pathogen levels and clinical response to periodontal treatment in patients with Interleukin 8 haplotypes [0.03%]
细胞因子基因型对牙周病原菌水平及疗效的影响研究
Livia S Finoti,Sâmia C T Corbi,Giovana Anovazzi et al.
Livia S Finoti et al.
The aim of this study was to investigate the effect of non-surgical treatment of periodontitis on the levels of periodontopathogens and clinical parameters in patients with different genetic backgrounds produced by polymorphisms in the Inte...
Role of Bordetella pertussis RseA in the cell envelope stress response and adenylate cyclase toxin release [0.03%]
百日咳博德特菌RseA蛋白在细胞壁应激反应和腺苷酸环化酶毒素释放中的作用
Tomoko Hanawa,Hideo Yonezawa,Hayato Kawakami et al.
Tomoko Hanawa et al.
Bordetella pertussis is the bacterial agent of the human disease such as whooping cough. In many bacteria, the extracellular function sigma factor σE is central to the response to envelope stress, and its activity is negatively controlled ...
Co-infection with Mycobacterium tuberculosis and human immunodeficiency virus: an overview and motivation for systems approaches [0.03%]
结核杆菌与人类免疫缺陷病毒共感染概述及系统方法的动机分析
Armin Deffur,Nicola J Mulder,Robert J Wilkinson
Armin Deffur
Tuberculosis is a devastating disease that accounts for a high proportion of infectious disease morbidity and mortality worldwide. HIV-1 co-infection exacerbates tuberculosis. Enhanced understanding of the host-pathogen relationship in HIV-...
Draft genome sequences of five recent human uropathogenic Escherichia coli isolates [0.03%]
五个近期尿源性致病大肠杆菌分离株的基因组草图序列
Sargurunathan Subashchandrabose,Tracy H Hazen,David A Rasko et al.
Sargurunathan Subashchandrabose et al.
This study reports the release of draft genome sequences of five isolates of uropathogenic Escherichia coli (UPEC), isolated from patients suffering from uncomplicated cystitis in 2012 in Ann Arbor, Michigan. Phylogenetic analyses revealed ...
Comparative Study
Pathogens and disease. 2013 Oct;69(1):66-70. DOI:10.1111/2049-632X.12059 2013
Chlamydia pneumoniae induces expression of pro-atherogenic factors through activation of the lectin-like oxidized LDL receptor-1 [0.03%]
肺炎衣原体通过激活类似氧化型低密度脂蛋白受体诱导动脉粥样硬化促病因子的表达
Lee A Campbell,Amy W Lee,Michael E Rosenfeld et al.
Lee A Campbell et al.
Several lines of evidence have associated Chlamydia pneumoniae with cardiovascular disease including acceleration of atherosclerotic lesion progression in hyperlipidemic animal models by infection. Many of the pro-atherogenic effects of oxi...
Host Organelle Hijackers: a similar modus operandi for Toxoplasma gondii and Chlamydia trachomatis: co-infection model as a tool to investigate pathogenesis [0.03%]
宿主细胞器劫持者：弓形虫和沙眼衣原体采用类似手段：共感染模型有助于研究致病机理
Julia D Romano,Isabelle Coppens
Julia D Romano
The bacterium Chlamydia trachomatis and the protozoan parasite Toxoplasma gondii are the causative agents of chlamydiosis and toxoplasmosis in humans, respectively. Both microorganisms are obligate intracellular pathogens and notorious for ...
Activation of influenza viruses by proteases from host cells and bacteria in the human airway epithelium [0.03%]
呼吸道上皮细胞和细菌的蛋白酶激活流感病毒
Eva Böttcher-Friebertshäuser,Hans-Dieter Klenk,Wolfgang Garten
Eva Böttcher-Friebertshäuser
Influenza is an acute infection of the respiratory tract, which affects each year millions of people. Influenza virus infection is initiated by the surface glycoprotein hemagglutinin (HA) through receptor binding and fusion of viral and end...
Hypericum hircinum L. components as new single-molecule inhibitors of both HIV-1 reverse transcriptase-associated DNA polymerase and ribonuclease H activities [0.03%]
Hypericum hircinum L．成分作为同时抑制HIV-1反转录酶DNA聚合酶和核糖核酸酶H活性的新单分子抑制剂
Francesca Esposito,Cinzia Sanna,Claudia Del Vecchio et al.
Francesca Esposito et al.
Among HIV-1 reverse transcriptase (RT)-associated functions, DNA polymerase and Ribonuclease H (RNase H) are both essential for HIV replication and excellent targets for drug development. While all RT inhibitors approved for therapy target ...
Antifungal and anticancer effects of a polysaccharide-protein complex from the gut bacterium Raoultella ornithinolytica isolated from the earthworm Dendrobaena veneta [0.03%]
从地表蚯蚓Dendrobaena veneta肠道细菌Raoultella ornithinolytica中分离的一种抗真菌和抗癌多糖蛋白复合物的效果
Marta J Fiołka,Kinga Lewtak,Jolanta Rzymowska et al.
Marta J Fiołka et al.
The polysaccharide-protein complex (PPC) isolated from metabolites of gut bacteria Raoultella ornithinolytica from Dendrobaena veneta earthworms exhibits activity against Candida albicans, in breast ductal carcinoma (line T47D) and in the e...