Invasion of differentiated intestinal Caco-2 cells is a sporadic property among atypical enteropathogenic Escherichia coli strains carrying common intimin subtypes [0.03%]
携带常见肠道致病性大肠杆菌intimins亚型的非典型肠道致病性大肠杆菌株侵袭分化型肠上皮细胞系Caco-2细胞的现象罕见
Veronica C R Pacheco,Denise Yamamoto,Cecilia M Abe et al.
Veronica C R Pacheco et al.
Atypical enteropathogenic Escherichia coli (aEPEC) strains produce attaching-effacing (AE) lesions on enterocytes due to the interaction of the adhesin intimin with its translocated receptor. aEPEC strain 1551-2 was previously shown to inva...
Comparative Study
Pathogens and disease. 2014 Mar;70(2):167-75. DOI:10.1111/2049-632X.12112 2014
Rothia dentocariosa induces TNF-alpha production in a TLR2-dependent manner [0.03%]
棒状乳杆菌通过依赖TLR2的方式诱导产生TNF-α
Hideo Kataoka,Makoto Taniguchi,Haruka Fukamachi et al.
Hideo Kataoka et al.
Previous work suggested that Rothia dentocariosa is associated with periodontal inflammatory disease. However, little is known about the pathogenicity of this bacterium. To characterize host response to this bacterium, we measured (via ELIS...
The route less taken: pulmonary models of enteric Gram-negative infection [0.03%]
不走寻常路：肺部模型中的肠源性革兰阴性菌感染
Michael L Fisher,Wei Sun,Roy Curtiss rd
Michael L Fisher
Many pathogens are capable of causing a fulminant infection in pulmonary tissues of mammals. Animal models have provided an extensive understanding of the genetic and molecular mechanisms of bacterial pathogenesis as well as host immune res...
HIV-Mycobacterium tuberculosis co-infection: a 'danger-couple model' of disease pathogenesis [0.03%]
HIV-结核杆菌共感染：疾病发病的“危险偶合模型”
Esaki M Shankar,Ramachandran Vignesh,Rada Ellegård et al.
Esaki M Shankar et al.
Tuberculosis (TB) and human immunodeficiency virus (HIV) infection interfere and impact the pathogenesis phenomena of each other. Owing to atypical clinical presentations and diagnostic complications, HIV/TB co-infection continues to be a m...
Lihua Song,John H Carlson,Bing Zhou et al.
Lihua Song et al.
Chlamydia trachomatis and C. muridarum are human and mouse pathogens, respectively, which show high conservation of gene order and content. Both species contain a common 7.5-kb plasmid that is an important virulence factor. Recently describ...
Inhibition of toll-like receptor 2 (TLR-2)-mediated response in human alveolar epithelial cells by mycolic acids and Mycobacterium tuberculosis mce1 operon mutant [0.03%]
分枝杆菌索状因子和结核分支杆菌mce1基因座突变株对人肺上皮细胞tlr-2介导信号通路的抑制作用
Patricia C Sequeira,Ryan H Senaratne,Lee W Riley
Patricia C Sequeira
In human lungs, the earliest encounter of Mycobacterium tuberculosis, the agent of tuberculosis, involves alveolar epithelial cells. Droplets expectorated by a patient with tuberculosis are likely to contain a mixed population of M. tubercu...
Draft genomes of 12 host-adapted and environmental isolates of Pseudomonas aeruginosa and their positions in the core genome phylogeny [0.03%]
绿脓杆菌12个菌株的草图基因组及其在核心基因组系统发育树中的位置
Lewis Stewart,Amy Ford,Vartul Sangal et al.
Lewis Stewart et al.
Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen particularly associated with the inherited disease cystic fibrosis (CF). Pseudomonas aeruginosa is well known to have a large and adaptable genome that enables it to colonise ...
Human antibody responses to pneumococcal surface protein A and capsular polysaccharides during acute and convalescent stages of invasive disease in adult patients [0.03%]
成人侵袭性肺炎链球菌感染急性期和恢复期患者表面蛋白A和荚膜多糖的免疫应答
Jan Kolberg,Audun Aase,Lisbeth M Naess et al.
Jan Kolberg et al.
The IgG antibody responses to pneumococcal surface protein A (PspA) and capsular polysaccharides in acute and convalescent-phase sera from 10 adult patients with invasive pneumococcal disease were analysed. The relatedness between the strai...
Gallium induces the production of virulence factors in Pseudomonas aeruginosa [0.03%]
镓诱导绿脓杆菌毒力因子的产生
Rodolfo García-Contreras,Berenice Pérez-Eretza,Elizabeth Lira-Silva et al.
Rodolfo García-Contreras et al.
The novel antimicrobial gallium is a nonredox iron III analogue with bacteriostatic and bactericidal properties, effective for the treatment of Pseudomonas aeruginosa in vitro and in vivo in mouse and rabbit infection models. It interferes ...
The synergies of microorganisms enlightened - convergent approaches to delineating coinfections [0.03%]
微生物的协同作用被照亮了——界定共感染的趋同方法
Hans-Dieter Klenk,Eliora Ron,Philippe Sansonetti et al.
Hans-Dieter Klenk et al.