Antifouling polyurethanes to fight device-related staphylococcal infections: synthesis, characterization, and antibiofilm efficacy [0.03%]
抗葡萄球菌感染防污型聚氨酯的合成、表征及抗菌膜功效
Iolanda Francolini,Gianfranco Donelli,Claudia Vuotto et al.
Iolanda Francolini et al.
In hospital settings, biofilm-based medical device-related infections are considered a threat to patients, the sessile growing bacteria playing a key role in the spreading of healthcare-associated infections. In recent decades, the design o...
TLR2 and TLR4 mediate the TNFα response to Vibrio vulnificus biotype 1 [0.03%]
TLR2和TLR4介导的创伤弧菌生物型1的TNFα反应
Lola V Stamm,Rebecca L Drapp
Lola V Stamm
Vibrio vulnificus (Vv) is a pathogenic bacterium that can cause life-threatening infections in humans. Most fatal cases are due to septic shock that results from dysregulation of cytokines, particularly TNFα, which plays a critical role in...
Multiple effects of Escherichia coli Nissle 1917 on growth, biofilm formation, and inflammation cytokines profile of Clostridium perfringens type A strain CP4 [0.03%]
大肠杆菌Nissle 1917菌株对A型产气荚膜梭菌CP4生长、生物被膜形成及促炎症细胞因子谱的作用研究
Yanlong Jiang,Qingke Kong,Kenneth L Roland et al.
Yanlong Jiang et al.
Clostridium perfringens is an important Gram-positive pathogen responsible for food poisoning, necrotic enteritis, gas gangrene, and even death. Escherichia coli Nissle 1917 (EcN) is a well-characterized probiotic strain with demonstrated b...
Differences in aerosolization of Rift Valley fever virus resulting from choice of inhalation exposure chamber: implications for animal challenge studies [0.03%]
吸入暴露箱的选择对裂谷热病毒气溶胶化的影响及其对动物攻毒试验的意义
Douglas S Reed,Laura M Bethel,Diana S Powell et al.
Douglas S Reed et al.
The aerosol characteristics of Rift Valley fever virus (RVFV) were evaluated to achieve reproducible infection of experimental animals with aerosolized RVFV suitable for animal efficacy studies. Spray factor (SF), the ratio between the conc...
Importance of biofilm formation and dipeptidyl peptidase IV for the pathogenicity of clinical Porphyromonas gingivalis isolates [0.03%]
牙龈卟啉单胞菌生物被膜的形成及二肽基肽酶Ⅳ与毒力之间的关系研究
Sofie Clais,Gaëlle Boulet,Monique Kerstens et al.
Sofie Clais et al.
The ability of Porphyromonas gingivalis to cause adult periodontitis is determined by its arsenal of virulence factors. Here, we investigated the importance of biofilm formation and bacterial dipeptidyl peptidase IV (DPPIV) for the pathogen...
Patrik Bavoil
Patrik Bavoil
Treatment of microbial biofilms in the post-antibiotic era: prophylactic and therapeutic use of antimicrobial peptides and their design by bioinformatics tools [0.03%]
后抗生素时代微生物生物被膜的治疗：抗菌肽及其设计工具的预防和治疗作用
Mariagrazia Di Luca,Giuseppe Maccari,Riccardo Nifosì
Mariagrazia Di Luca
The treatment for biofilm infections is particularly challenging because bacteria in these conditions become refractory to antibiotic drugs. The reduced effectiveness of current therapies spurs research for the identification of novel molec...
Proteomic strategies for the discovery of novel diagnostic and therapeutic targets for infectious diseases [0.03%]
用于感染性疾病诊断和治疗的新靶标鉴定的蛋白质组学策略
Moushimi Amaya,Alan Baer,Kelsey Voss et al.
Moushimi Amaya et al.
Viruses have developed numerous and elegant strategies to manipulate the host cell machinery to establish a productive infectious cycle. The interaction of viral proteins with host proteins plays an important role in infection and pathogene...
Barry Rockx
Barry Rockx
Hendra (HeV) and Nipah (NiV) viruses (genus Henipavirus (HNV; family Paramyxoviridae) are emerging zoonotic agents that can cause severe respiratory distress and acute encephalitis in humans. Given the lack of effective therapeutics and vac...
Morten Alhede,Özge Er,Steffen Eickhardt et al.
Morten Alhede et al.
Injection of soft tissue fillers plays an important role in facial reconstruction and esthetic treatments such as cosmetic surgery for lip augmentation and wrinkle smoothening. Adverse events are an increasing problem, and recently, it has ...