Assessment of long-term adverse events regarding different COVID-19 vaccine regimens within an 18-month follow-up study [0.03%]
一项18个月的随访研究评估了不同新冠疫苗接种方案的长期不良事件
Mona Sadat Larijani,Rahim Sorouri,Sana Eybpoosh et al.
Mona Sadat Larijani et al.
Early reports on coronavirus disease 2019 (COVID-19) vaccines presented the short-term adverse events (AEs). This follow-up study investigated a standard regimen based on protein subunit vaccines, PastoCovac and PastoCovac Plus, and the com...
Comparative transcriptomics and genomics from continuous axenic media growth identifies Coxiella burnetii intracellular survival strategies [0.03%]
转录组学和基因组学的比较分析揭示连续无菌培养条件下贝纳氏柯克斯体细胞内存活策略
Archana Yadav,Melissa N Brewer,Mostafa S Elshahed et al.
Archana Yadav et al.
Coxiella burnetii (Cb) is an obligate intracellular pathogen in nature and the causative agent of acute Q fever as well as chronic diseases. In an effort to identify genes and proteins crucial to their normal intracellular growth lifestyle,...
Using quotients as a mentor to facilitate the success of underrepresented students [0.03%]
利用商数作为指导来促进被忽视学生群体的成功
Kit Neikirk,Taylor Barongan,Tiffany Rolle et al.
Kit Neikirk et al.
Choosing a mentor requires a certain level of introspection for both the mentor and the mentee. The dynamics of mentorship may change depending on the academic status of the mentee. Regardless, mentors should help their trainees grow both a...
Uncovering the role of microRNA671-5p/CDCA7L/monoamine oxidase-A signaling in Helicobacter pylori mediated apoptosis in gastric epithelial cells [0.03%]
揭秘MicroRNA671-5p/CDCA7L/单胺氧化酶-A信号在幽门螺旋杆菌介导的胃上皮细胞凋亡中的作用
Thurbu Tshering Lepcha,Manish Kumar,Arun Kumar Sharma et al.
Thurbu Tshering Lepcha et al.
Helicobacter pylori is a gram-negative microaerophilic bacterium and is associated with gastrointestinal diseases ranging from peptic ulcer and gastritis to gastric cancer and mucosa-associated lymphoid tissue lymphoma. In our laboratory, t...
Meropenem in combination with baicalein exhibits synergism against extensively drug resistant and pan-drug-resistant Acinetobacter baumannii clinical isolates in vitro [0.03%]
美罗培南联合黄芩素对体外分离的多重耐药鲍曼不动杆菌菌株具有协同作用
Mümtaz Güran,Kadir Çakıral,Kerem Teralı et al.
Mümtaz Güran et al.
Several studies have demonstrated that the effectiveness of carbapenems against drug-resistant Acinetobacter baumannii infections has been decreasing. Combination therapy with two or more drugs is currently under investigation to overcome t...
Comparative study of GBP recruitment on two cytosol-dwelling pathogens, Francisella novicida and Shigella flexneri highlights differences in GBP repertoire and in GBP1 motif requirements [0.03%]
针对胞质病原体福氏耐万古霉素肠球菌和志贺毒素的作用机制的研究表明GBP repertoires的不同及GBP1基序的需求不同
Stanimira V Valeva,Manon Degabriel,Fanny Michal et al.
Stanimira V Valeva et al.
Guanylate-Binding Proteins are interferon-inducible GTPases that play a key role in cell autonomous responses against intracellular pathogens. Despite sharing high sequence similarity, subtle differences among GBPs translate into functional...
Murine herpesvirus-68-related growth factors treatment correlates with decrease of p53 and HIF-1α protein levels [0.03%]
与p53和HIF-1α蛋白水平降低相关的鼠68型疱疹病毒相关生长因子治疗
Miroslava Supolikova,Eva Novakova,Karin Donatova et al.
Miroslava Supolikova et al.
Murine herpesvirus 68 (MHV-68) belongs to the subfamily Gammaherpesvirinae of the family Herpesviridae. This exceptional murine herpesvirus is an excellent model for the study of human gammaherpesvirus infections. Cells infected with MHV-68...
The Burkholderia contaminans prevalent phenotypes as possible markers of poor clinical outcomes in chronic lung infection of children with cystic fibrosis [0.03%]
Burkholderia contaminans优势表型可能成为囊性纤维化儿童慢性肺部感染预后不良的标志物
Beltina León,Claudia Prieto,Marisa Bettiol et al.
Beltina León et al.
Burkholderia contaminans, a species of the Burkholderia cepacia complex-prevalent in certain Latin-American and European countries-can cause chronic pulmonary infection in persons with cystic fibrosis. Our aim was to gain insights into long...
Induction and sustenance of antibacterial activities distinguishes response of mice to Salmonella Typhi from response to Salmonella Typhimurium [0.03%]
小鼠对伤寒沙门氏菌的免疫反应与对肠炎沙门氏菌的免疫反应的区别：前者能够产生诱导和维持抗菌活性的作用
Jitender Yadav,Ayub Qadri
Jitender Yadav
Salmonella enterica serovar Typhi (S. Typhi), the causative agent of typhoid in humans, shares a high degree of homology with a closely related serovar, S. Typhimurium. Yet, unlike S. Typhimurium, S. Typhi does not establish infection in mi...
In vitro and in vivo evaluation of DNase I in reinstating antibiotic efficacy against Klebsiella pneumoniae biofilms [0.03%]
DNase I恢复肺炎克雷伯菌生物膜中抗生素有效性的体内外评估
Anayata Sharma,Praveen Rishi,Rachna Singh
Anayata Sharma
Klebsiella pneumoniae is an opportunistic pathogen associated with biofilm-based infections, which are intrinsically antibiotic resistant. Extracellular DNA plays a crucial role in biofilm formation and self-defence, with nucleases being pr...