Colonization efficiency of multidrug-resistant Neisseria gonorrhoeae in a female mouse model [0.03%]
耐多药淋球菌在雌性小鼠模型中的定植效率研究
Babatomiwa Kikiowo,Aloka B Bandara,Nader S Abutaleb et al.
Babatomiwa Kikiowo et al.
The rapid occurrence of gonococcal resistance to all classes of antibiotics could lead to untreatable gonorrhea. Thus, development of novel anti-Neisseria gonorrhoeae drugs is urgently needed. Neisseria gonorrhoeae FA1090 is the most used i...
Impact of IL-17-producing γδ T cells on chronic otitis media induced by nontypeable Haemophilus influenzae in a mouse model [0.03%]
IL-17产生型γδT细胞在非典型流感嗜血杆菌诱导的小鼠慢性中耳炎中的作用研究
Takashi Hirano,Toshiaki Kawano,Yoshinori Kadowaki et al.
Takashi Hirano et al.
Nontypeable Haemophilus influenzae (NTHi) is considered a major pathogen underlying middle ear infection. This study aimed to investigate the impact of IL-17 on chronic otitis media (COM) induced by NTHi in mice. NTHi was inoculated into th...
Oxidative profile, inflammatory responses and δ-aminolevulinate dehydratase enzyme activity in influenza B virus infection [0.03%]
乙型流感病毒性感冒的氧化状况、炎症反应及δ-氨基叶酸脱水酶活性的研究
Jovana Simonetti Bulegon,Andressa de Azambuja Pias Weber,Manoela Dias de Souza et al.
Jovana Simonetti Bulegon et al.
The aim of the current study was to determine the activity of the delta-aminolevulinate dehydratase (δ-ALA-D) enzyme, oxidative stress biomarkers and the expression of cytokines in those infected with influenza B virus (IBV). To evaluate t...
TargeTron inactivation of plasmid-regulated Chlamydia trachomatis CT084 results in a nonlytic phenotype [0.03%]
靶向失活调节沙眼衣原体质粒的CT084基因产生非裂解感染表型
Una Karanovic,Lei Lei,Craig A Martens et al.
Una Karanovic et al.
Chlamydia trachomatis is an obligate intracellular bacterium that causes blinding trachoma and sexually transmitted disease. The chlamydial plasmid is a critical virulence factor in the pathogenesis of these diseases. Plasmid gene protein 4...
Antentor Hinton,Haysetta D Shuler
Antentor Hinton
Our editorial focused on the concept of "Making the Invisible Visible in Science, Technology, Engineering, Mathematics, and Medicine (STEMM)." We highlight 11 manuscripts submitted to our research topic, which offer unique and innovative, e...
Infectious and environmental placental insults: from underlying biological pathways to diagnostics and treatments [0.03%]
感染和环境因素对胎盘的影响：从潜在的生物学途径到诊断和治疗
Samuel Chenge,Harrison Ngure,Bernard N Kanoi et al.
Samuel Chenge et al.
Because the placenta is bathed in maternal blood, it is exposed to infectious agents and chemicals that may be present in the mother's circulation. Such exposures, which do not necessarily equate with transmission to the fetus, may primaril...
Bald sea urchin disease shifts the surface microbiome on purple sea urchins in an aquarium [0.03%]
无毛海胆疾病会改变水族馆中紫色海胆的表面微生物群
Chloe G Shaw,Christina Pavloudi,Megan A Barela Hudgell et al.
Chloe G Shaw et al.
Bald sea urchin disease (BSUD) is most likely a bacterial infection that occurs in a wide range of sea urchin species and causes the loss of surface appendages. The disease has a variety of additional symptoms, which may be the result of th...
Immunogenicity evaluation of a novel virus-like particle vaccine candidate against SARS-CoV-2 in BALB/c [0.03%]
BALB/c小鼠中新型SARS-CoV-2病毒样颗粒候选疫苗的免疫原性评价
Golnaz Bahramali,Maryam Mashhadi Abolghasem Shirazi,Mina Hannan et al.
Golnaz Bahramali et al.
The coronavirus disease (COVID-19) pandemic has imposed deployment of an effective vaccine as a worldwide health priority. The new variants of SARS-CoV-2 have also brought serious concerns due to virus eradiation hesitancy. In this study, w...
High prevalence of GR2 and GR4 plasmids in Acinetobacter baumannii strains from Brazil [0.03%]
巴西鲍曼不动杆菌中GR2和GR4质粒的高流行率
Beatriz Souza Toscano de Melo,Danilo Elias Xavier,Nilma Cintra Leal et al.
Beatriz Souza Toscano de Melo et al.
Acinetobacter baumannii is Gram-negative pathogen with extensive role in healthcare-associated infections (HAIs). Plasmids in this species are important carriers of antimicrobial resistance genes. In this work, we investigated the plasmids ...