Interplay between gut microbiota and the master iron regulator, hepcidin, in the pathogenesis of liver fibrosis [0.03%]
肠道微生物群和主铁调节因子血色素素在肝纤维化发病机制中的相互作用
Sara Ahmadi Badi,Ahmad Bereimipour,Pejman Rohani et al.
Sara Ahmadi Badi et al.
Introduction: There is a proven role for hepcidin and the composition of gut microbiota and its derivatives in the pathophysiology of liver fibrosis. Area...
Feng-Yuan Zhang,Ni Lian,Min Li
Feng-Yuan Zhang
Candida albicans (C. albicans) is a prevalent opportunistic pathogen that causes mucocutaneous and systemic infections, particularly in immunocompromised individuals. Macrophages play a crucial role in eliminating C. albicans in local and b...
Awakening the sleeping giant: Epstein-Barr virus reactivation by biological agents [0.03%]
唤醒沉睡的巨人：生物制剂引起的Epstein-Barr病毒活化
Omkar Indari,Subhrojyoti Ghosh,Adhiraj Singh Bal et al.
Omkar Indari et al.
Epstein-Barr virus (EBV) may cause harm in immunocompromised conditions or on stress stimuli. Various chemical agents have been utilized to induce the lytic cycle in EBV-infected cells. However, apart from chemical agents and external stres...
In vitro effects of selective serotonin reuptake inhibitors on Cryptococcus gattii capsule and biofilm [0.03%]
选择性5-羟色胺再摄取抑制剂对隐球菌荚膜和生物被膜的体外影响
Letícia Rampazzo da Gama Viveiro,Amanda Rodrigues Rehem,Evelyn Luzia De Souza Santos et al.
Letícia Rampazzo da Gama Viveiro et al.
Infections caused by Cryptococcus gattii mainly affect immunocompetent individuals and the treatment presents important limitations. This study aimed to validate the efficacy of selective serotonin reuptake inhibitors (SSRI), fluoxetine hyd...
Zhe-Yu Peng,Song Yang,Hong-Zheng Lu et al.
Zhe-Yu Peng et al.
Zika virus (ZIKV), which belongs to the Flavivirus family, is mainly transmitted via the bite of Aedes mosquitoes. In newborns, ZIKV infection can cause severe symptoms such as microcephaly, while in adults, it can lead to Guillain‒Barré ...
The potential role of protein disulfide isomerases (PDIs) during parasitic infections: a focus on Leishmania spp [0.03%]
蛋白二硫异构酶(PDIs)在寄生虫感染中的潜在作用：以利什曼原虫为例
Majid Dousti,Masoumeh Hosseinpour,Nadia D Ghasemi et al.
Majid Dousti et al.
Leishmaniasis is a group of vector-borne diseases caused by intracellular protozoan parasites belonging to the genus Leishmania. Leishmania parasites can employ different and numerous sophisticated strategies, including modulating host prot...
Bordetella pertussis targets the basolateral membrane of polarized respiratory epithelial cells, gets internalized, and survives in intracellular locations [0.03%]
百日咳博德特菌靶向呼吸道上皮极化细胞的基底外侧膜，并在细胞内特定部位被摄取并存活下来
Carlos Manuel Baroli,Juan Pablo Gorgojo,Bruno Martín Blancá et al.
Carlos Manuel Baroli et al.
The airway epithelial barrier is a continuous highly organized cell layer that separates the exterior from the underlying mucosal tissue, preventing pathogen invasion. Several respiratory pathogens have evolved mechanisms to compromise this...
Richard A Stein,Lily M Thompson
Richard A Stein
Chlamydia trachomatis, C. pneumoniae, and C. psittaci, the three Chlamydia species known to cause human disease, have been collectively linked to several pathologies, including conjunctivitis, trachoma, respiratory disease, acute and chroni...
Nur77 influences immunometabolism to regulate the release of proinflammatory cytokines and the formation of lipid bodies during Mycobacterium tuberculosis infection of macrophages [0.03%]
Nur77通过调节巨噬细胞中结核杆菌感染引发的炎症因子释放和脂滴形成来影响免疫代谢
Pankaj Birari,Soumya Mal,Debayan Majumder et al.
Pankaj Birari et al.
Infection of macrophages with Mycobacterium tuberculosis induces innate immune responses designed to clear the invading bacterium. However, bacteria often survive within the intracellular environment by exploiting these responses triggered ...
Myeloid miR-155 plays a limited role in antibacterial defense during Klebsiella-derived pneumosepsis and is dispensable for lipopolysaccharide- or Klebsiella-induced inflammation in mice [0.03%]
小胶质细胞源性miR-155在条件性肺炎血症小鼠细菌感染免疫应答中作用有限，并非脂多糖或条件致病菌诱导的炎症所必需
Wanhai Qin,Anno Saris,Cornelis van &#x;t Veer et al.
Wanhai Qin et al.
MicroRNA-155 (miR-155) plays a crucial role in regulating host inflammatory responses during bacterial infection. Previous studies have shown that constitutive miR-155 deficiency alleviates inflammation while having varying effects in diffe...