Differential patterns of antibody response against SARS-CoV-2 nucleocapsid epitopes detected in sera from patients in the acute phase of COVID-19, convalescents, and pre-pandemic individuals [0.03%]
针对SARS-CoV-2核衣壳表位的抗体反应的不同模式：来自急性期COVID-19患者、康复者和大流行前个体血清的研究
Agnieszka Razim,Katarzyna Pacyga-Prus,Wioletta Kazana-Płuszka et al.
Agnieszka Razim et al.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has already infected more than 0.7 billion people and caused over 7 million deaths worldwide. At the same time, our knowledge about this virus is still incipient. In some case...
Optimal protein allocation controls the inhibition of GltA and AcnB in Neisseria gonorrhoeae [0.03%]
最优蛋白质分配控制淋病奈瑟菌中GltA和AcnB的抑制作用
Nabia Shahreen,Niaz Bahar Chowdhury,Rajib Saha
Nabia Shahreen
Neisseria gonorrhea (Ngo) is a major concern for global public health due to its severe implications for reproductive health. Understanding its metabolic phenotype is crucial for comprehending its pathogenicity. Despite Ngo's ability to enc...
Mechanisms that potentially contribute to the development of post-streptococcal glomerulonephritis [0.03%]
可能导致链球菌后肾小球肾炎发病的机制
Mohammad Raguib Munif,Robert A Hart,Rukshan A M Rafeek et al.
Mohammad Raguib Munif et al.
Post-streptococcal glomerulonephritis (PSGN) is primarily associated with preceding group A streptococcal skin or throat infections, now mainly observed in economically disadvantaged communities. This condition significantly predisposes ind...
Natural products and derivatives as Japanese encephalitis virus antivirals [0.03%]
天然产物及其衍生物作为治疗日本脑炎病毒的抗病毒药物
Yunqi Mi,Yan Guo,Xuliang Luo et al.
Yunqi Mi et al.
Japanese encephalitis virus (JEV) causes acute Japanese encephalitis (JE) in humans and reproductive disorders in pigs. There are ~68 000 cases of JE worldwide each year, with ~13 600-20 400 deaths. JE infections have a fatality rate of one...
A suitable and efficient optimization system for the culture of Chlamydia trachomatis in adult inclusion conjunctivitis [0.03%]
适于优化沙眼衣原体成人包涵体结膜炎培养的体系
Yuan Wei,Xizhan Xu,Leying Wang et al.
Yuan Wei et al.
The prevalence of Chlamydia trachomatis infection in the genitourinary tract is increasing, with an annual rise of 9 million cases. Individuals afflicted with these infections are at a heightened risk of developing adult inclusive conjuncti...
Restriction and evasion: a review of IFNγ-mediated cell-autonomous defense pathways during genital Chlamydia infection [0.03%]
限制与逃避：生殖道沙眼衣原体感染过程中细胞自主防御途径的干扰素γ介导机制综述
Jeffrey R Reitano,Jörn Coers
Jeffrey R Reitano
Chlamydia trachomatis is the most common cause of bacterial sexually transmitted infection (STI) in the USA. As an STI, C. trachomatis infections can cause inflammatory damage to the female reproductive tract and downstream sequelae includi...
David R Thomas,Sarah E Garnish,Chen Ai Khoo et al.
David R Thomas et al.
Coxiella burnetii is a globally distributed obligate intracellular pathogen. Although often asymptomatic, infections can cause acute Q fever with influenza-like symptoms and/or severe chronic Q fever. Coxiella burnetii develops a unique rep...
Taylor B Poston
Taylor B Poston
Chlamydia trachomatis is the most prevalent bacterial sexually transmitted infection globally. Antibiotic treatment is highly effective, but infection is often asymptomatic resulting in most individuals going undetected and untreated. This ...
Sphingosine kills intracellular Pseudomonas aeruginosa and Staphylococcus aureus [0.03%]
鞘氨醇能杀死胞内铜绿假单胞菌和金黄色葡萄球菌
Helene May,Yongjie Liu,Stephanie Kadow et al.
Helene May et al.
Sphingosine has been previously shown to kill many strains of pathogenic bacteria including Pseudomonas aeruginosa, Staphyloccus aureus, Acinetobacter, and atypical mycobacteria. However, these studies were performed on isolated or extracel...
In silico design and analysis of a multiepitope vaccine against Chlamydia [0.03%]
基于计算的解产组织卡淋巴门体疫苗设计及分析
Tayhlor Tanner,F N U Medhavi,Shakyra Richardson et al.
Tayhlor Tanner et al.
Chlamydia trachomatis (Ct) is the most common sexually transmitted bacterial infection worldwide, potentially leading to severe pathologies including pelvic inflammatory disease, ectopic pregnancy, and tubal infertility if left untreated. C...