The growing repertoire of genetic tools for dissecting chlamydial pathogenesis [0.03%]
日益增多的遗传工具在沙眼衣原体致病机理研究中的应用
Arkaprabha Banerjee,David E Nelson
Arkaprabha Banerjee
Multiple species of obligate intracellular bacteria in the genus Chlamydia are important veterinary and/or human pathogens. These pathogens all share similar biphasic developmental cycles and transition between intracellular vegetative reti...
Virulence potential of Rickettsia amblyommatis for spotted fever pathogenesis in mice [0.03%]
一种以边际多刺蜱为媒介的立克次氏体的致病性潜力研究
Wan-Yi Yen,Kayla Stern,Smruti Mishra et al.
Wan-Yi Yen et al.
Rickettsia amblyommatis belongs to the spotted fever group of Rickettsia and infects Amblyomma americanum (Lone Star ticks) for transmission to offspring and mammals. Historically, the geographic range of A. americanum was restricted to the...
Juliana Campos Junqueira,Eleftherios Mylonakis,Elisa Borghi
Juliana Campos Junqueira
The GBP1 microcapsule interferes with IcsA-dependent septin cage assembly around Shigella flexneri [0.03%]
GBP1微囊抑制缠绕于宋内志贺菌周围的依赖IcsA的Septin笼组装
Miriam Kutsch,Coral González-Prieto,Cammie F Lesser et al.
Miriam Kutsch et al.
Many cytosolic bacterial pathogens hijack the host actin polymerization machinery to form actin tails that promote direct cell-to-cell spread, enabling these pathogens to avoid extracellular immune defenses. However, these pathogens are sti...
MicroRNA-139-5p inhibits inflammatory and oxidative stress responses of Salmonella-infected macrophages through modulating TRAF6 [0.03%]
微小核糖核酸-139-5p通过调节TRAF6抑制感染 salmonella 的巨噬细胞的炎症和氧化应激反应
Xiaohong Xu,Tingyun Ye,Yizhang Wang et al.
Xiaohong Xu et al.
Evidence indicates that macrophages play an important role in the immune system. Therefore, research involving inflammatory and oxidative stress responses in macrophages is of great significance. Many factors contribute to inflammation and ...
The genus Anaplasma: drawing back the curtain on tick-pathogen interactions [0.03%]
解开关节虫和病原体相互作用的面纱——安纳普拉属细菌
Anya J O&#x;Neal,Nisha Singh,Maria Tays Mendes et al.
Anya J O&#x;Neal et al.
Tick-borne illnesses pose a serious concern to human and veterinary health and their prevalence is on the rise. The interactions between ticks and the pathogens they carry are largely undefined. However, the genus Anaplasma, a group of tick...
The enigmatic biology of rickettsiae: recent advances, open questions and outlook [0.03%]
立克次氏体错综复杂的生物学：近期研究进展、悬而未决的问题及未来展望
Jon McGinn,Rebecca L Lamason
Jon McGinn
Rickettsiae are obligate intracellular bacteria that can cause life-threatening illnesses and are among the oldest known vector-borne pathogens. Members of this genus are extraordinarily diverse and exhibit a broad host range. To establish ...
Dynamic gene expression in salivary glands of the cat flea during Rickettsia felis infection [0.03%]
猫蚤感染立克次氏体期间唾液腺的动态基因表达调控研究
Monika Danchenko,Hanna J Laukaitis,Kevin R Macaluso
Monika Danchenko
The cat flea, Ctenocephalides felis, is an arthropod vector capable of transmitting several human pathogens including Rickettsia species. Earlier studies identified Rickettsia felis in the salivary glands of the cat flea and transmission of...
Incidence, drivers and global health implications of the 2019/2020 yellow fever sporadic outbreaks in Sub-Saharan Africa [0.03%]
2019-2020年撒哈拉以南非洲地区黄热病散发疫情的流行、驱动因素及全球卫生影响
Anthony Uchenna Emeribe,Idris Nasir Abdullahi,Odunayo O R Ajagbe et al.
Anthony Uchenna Emeribe et al.
The 2019 and 2020 sporadic outbreaks of yellow fever (YF) in Sub-Saharan African countries had raised a lot of global health concerns. This article aims to narratively review the vector biology, YF vaccination program, environmental factors...
Take my breath away: studying pathogen invasion of the human lung using primary tissue models [0.03%]
屏住呼吸：利用主要组织模型研究病原体入侵人体肺部
Amanda L Dragan,Daniel E Voth
Amanda L Dragan
The human pulmonary environment is complex, containing a matrix of cells, including fibroblasts, epithelial cells, interstitial macrophages, alveolar macrophages and neutrophils. When confronted with foreign material or invading pathogens, ...