Leonurine protects against influenza A virus infection-induced pneumonia in mice [0.03%]
莱诺碱对A型流感病毒诱导的小鼠肺炎具有保护作用
Li-Nan Qiu,Ya-Rong Tan,Yu-Ju Luo et al.
Li-Nan Qiu et al.
Influenza A virus (H1N1), a swine-origin influenza A virus, causes seasonal epidemics that result in severe illnesses and deaths. Leonurine has been reported to function as an anti-inflammatory agent with protective effects on nervous, urin...
Jason R Hunt,Jason A Carlyon
Jason R Hunt
Orientia tsutsugamushi is an obligate intracellular bacterium that causes scrub typhus, a potentially fatal rickettsiosis, and for which no genetic tools exist. Critical to addressing this technical gap is to identify promoters for driving ...
Minireview: Epidemiological impact of arboviral diseases in Latin American countries, arbovirus-vector interactions and control strategies [0.03%]
拉美国家蚊媒疾病的影响、蚊媒病毒与载体的相互作用及控制策略简述
Nidya A Segura,Ana L Muñoz,Mónica Losada-Barragán et al.
Nidya A Segura et al.
Mosquitoes are the most crucial insects in public health due to their vector capacity and competence to transmit pathogens, including arboviruses, bacterias and parasites. Re-emerging and emerging arboviral diseases, such as yellow fever vi...
Invasion of the choroid plexus epithelium by Neisseria meningitidis is differently mediated by Arp2/3 signaling and possibly by dynamin dependent on the presence of the capsule [0.03%]
无菌性脑膜炎球菌以不同的方式入侵脉络丛上皮细胞，这可能取决于是否存在荚膜以及肌动蛋白聚合和胞质动力相关蛋白的作用
Rosanna Herold,Gina Sünwoldt,Carolin Stump-Guthier et al.
Rosanna Herold et al.
Neisseria meningitis (Nm) is a human-specific bacterial pathogen that can cause sepsis and meningitis. To cause meningitis Nm must enter the central nervous system (CNS) across one of the barriers between the blood and the brain. We have pr...
Toxic stress and burnout: John Henryism and social dominance in the laboratory and STEM workforce [0.03%]
有毒压力和精疲力竭：“约翰·亨利主义”与实验室及STEM行业的社会支配性
Tiffany Rolle,Zer Vue,Sandra A Murray et al.
Tiffany Rolle et al.
Persons Excluded from science because of Ethnicity and Race (PEERs) face chronic exposure to interpersonal stressors, such as social discrimination, throughout their scientific careers, leading to a long-term decline in physical and mental ...
Larval excretion/secretion of dipters of Lucilia cuprina species induces death in promastigote and amastigote forms of Leishmania amazonensis [0.03%]
Lucilia cuprina种蝇幼虫的排泄/分泌产物诱导Leishmania amazonensis促进型和无鞭毛体阶段死亡
Ana Carolina Jacob Rodrigues,Bruna Taciane da Silva Bortoleti,Amanda Cristina Machado Carloto et al.
Ana Carolina Jacob Rodrigues et al.
Leishmaniasis is a neglected tropical disease that affects millions of people around the world. Larval excretion/secretion (ES) of the larvae of flies of the Calliphoridae family has microbicidal activity against Gram-positive and Gram-nega...
Shifting proteomes: limitations in using the BioID proximity labeling system to study SNARE protein trafficking during infection with intracellular pathogens [0.03%]
蛋白质组的转变：使用BioID邻近标记系统研究细胞内病原体感染期间SNARE蛋白转运的局限性
Lisa M Jorgenson,Macy G Olson-Wood,Elizabeth A Rucks
Lisa M Jorgenson
We hypothesize that intracellular trafficking pathways are altered in chlamydial infected cells to maximize the ability of Chlamydia to scavenge nutrients while not overtly stressing the host cell. Previous data demonstrated the importance ...
Intentional mentoring: maximizing the impact of underrepresented future scientists in the 21st century [0.03%]
有意图的指导：在21世纪最大限度地提高少数族裔未来科学家的影响
Haysetta Shuler,Victor Cazares,Andrea Marshall et al.
Haysetta Shuler et al.
Mentoring is a developmental experience intended to increase the willingness to learn and establish credibility while building positive relationships through networking. In this commentary, we focus on intentional mentoring for underreprese...
Caner Özdemir,Nefise Akçelik,Fatma Neslihan Özdemir et al.
Caner Özdemir et al.
The effects of the bcsE gene and BcsE protein on bacterial physiology and pathogenicity in SalmonellaTyphimurium and Salmonella Group C1 were investigated. It was observed that biofilm and pellicle formation did not occur in the bcsE gene m...
Knockdown of METTL3 inhibits enterovirus 71-induced apoptosis of mouse Schwann cell through regulation of autophagy [0.03%]
METTL3敲低通过调控自噬抑制神经胶质细胞病毒诱发的小鼠施万细胞凋亡
Yulian Xiao,Yanping Yang,Dandan Hu
Yulian Xiao
Enterovirus A71 (EV-A71 or EV-71) is an RNA virus that causes hand, foot and mouse disease in children. The N6-methyladenosine (m6A) of RNA is a common RNA modification involved in various biological events. METTL3 is an m6A methyltransfera...