Mycoplasma decontamination in Chlamydia trachomatis culture: a curative approach [0.03%]
沙眼衣原体培养中的支原体净化：一种根治策略
Madison Greer,Jacob H Elnaggar,Christopher M Taylor et al.
Madison Greer et al.
Mycoplasma contamination of cell culture represents a serious problem in research and decontamination from cell-propagated obligate intracellular bacteria has proven challenging. Here, we presented an optimized protocol to remove Mycoplasma...
Can't live outside you: a thematic issue on obligate intracellular bacterial pathogens [0.03%]
离不开你：专性细胞内细菌病原菌主题专辑
Jörn Coers,Hayley J Newton,Jason A Carlyon
Jörn Coers
Keeping the host alive - lessons from obligate intracellular bacterial pathogens [0.03%]
让宿主保持活力 - 从强制细胞内细菌病原体获得的教训
Robson Kriiger Loterio,Dario S Zamboni,Hayley J Newton
Robson Kriiger Loterio
Mammals have evolved sophisticated host cell death signaling pathways as an important immune mechanism to recognize and eliminate cell intruders before they establish their replicative niche. However, intracellular bacterial pathogens that ...
Identification of histone H2B as a potential receptor for Mycoplasma genitalium protein of adhesion [0.03%]
组蛋白H2B作为人型支原体粘附蛋白受体的鉴定
Yating Liao,Xiangying Deng,Kailan Peng et al.
Yating Liao et al.
Mycoplasma genitalium, the smallest prokaryotic microorganism capable of independent replication, is increasingly recognized as a sexually transmitted pathogen. M. genitalium protein of adhesion (MgPa) plays a pivotal role in the process of...
Delineating infection strategies of Leishmania donovani secretory proteins in Human through host-pathogen protein Interactome prediction [0.03%]
通过宿主病原蛋白互作组预测描绘利什曼原虫分泌蛋白质在人体中的感染策略
Gauri Panditrao,Piyali Ganguli,Ram Rup Sarkar
Gauri Panditrao
Interactions of Leishmania donovani secretory virulence factors with the host proteins and their interplay during the infection process in humans is poorly studied in Visceral Leishmaniasis. Lack of a holistic study of pathway level de-regu...
A bioinformatics approach to investigate serum and hematopoietic cell-specific therapeutic microRNAs targeting the 3' UTRs of all four Dengue virus serotypes [0.03%]
针对所有四种登革热病毒血清型的3'UTR研究血清和造血细胞特异性治疗microRNAs的生物信息学方法
Mirza Sarwar Baig,Anuja Krishnan
Mirza Sarwar Baig
Hyperendemic circulation of all four Dengue virus (DENV) serotypes is a severe global public health problem, so any vaccine or therapeutics should be able to target all four of them. Cells of hemopoietic origin are believed to be primary si...
Combination of kaempferol and azithromycin attenuates Staphylococcus aureus-induced osteomyelitis via anti-biofilm effects and by inhibiting the phosphorylation of ERK1/2 and SAPK [0.03%]
黄酮和阿奇霉素的组合通过抗生物膜作用以及抑制ERK1/2和SAPK的磷酸化减轻金黄色葡萄球菌诱导的骨髓炎
Lei Gao,Zhipeng Tang,Tianbo Li et al.
Lei Gao et al.
Osteomyelitis is bacterial infection of bone, commonly caused by Staphylococcus aureus. This work aims to study the potential of azithromycin and kaempferol against chronic osteomyelitis induced by azithromycin-resistant Staphylococcus aure...
Virophages: association with human diseases and their predicted role as virus killers [0.03%]
病毒噬菌体：与人类疾病的关联及其作为病毒杀手的预测作用
Debrupa Dutta,Velayutham Ravichandiran,Soumi Sukla
Debrupa Dutta
The fascinating discovery of the first giant virus, Acanthamoeba polyphaga mimivirus (APMV), belonging to the family Mimiviridae in 2008, and its associated virophage, Sputnik, have left the world of microbiology awestruck. To date, about 1...
A novel hypermucoviscous Klebsiella pneumoniae ST3994-K2 clone belonging to Clonal Group 86 [0.03%]
属于克隆群86的一种新型高粘液型肺炎克雷伯菌ST3994-K2克隆
Louise Cerdeira,Rafael Nakamura-Silva,Mariana Oliveira-Silva et al.
Louise Cerdeira et al.
Emergent hypervirulent Klebsiella pneumoniae has been responsible for severe diseases, representing a serious threat to public health. We report the whole-genome sequencing of a novel ST3994-K2 clone, a single locus variant of ST86 K2, whic...
Computational analysis of human host binding partners of chikungunya and dengue viruses during coinfection [0.03%]
联合感染期间对人类宿主绑定伙伴的基孔肯雅病毒和登革热病毒的计算分析
Ritu Ghildiyal,Reema Gabrani
Ritu Ghildiyal
Mosquito-borne viral diseases like chikungunya and dengue infections can cause severe illness and have become major public health concerns. Chikungunya virus (CHIKV) and dengue virus (DENV) infections share similar primary clinical manifest...