Irradiated wild-type and Spa mutant Staphylococcus aureus induce anti-S. aureus immune responses in mice which do not protect against subsequent intravenous challenge [0.03%]
辐照的金黄色葡萄球菌野生型和Spa突变体诱导小鼠产生抗金黄色葡萄球菌免疫反应但不能保护其免受静脉内攻击
Pauline M van Diemen,Yuko Yamaguchi,Gavin K Paterson et al.
Pauline M van Diemen et al.
Staphylococcus aureus remains an important human and animal pathogen. Its pathogenicity is determined in part by expression of the Spa-immune subversion protein, neutralising the activity of which provides partial protection in murine model...
Serum antibody response to group II chaperonin from Methanobrevibacter oralis and human chaperonin CCT [0.03%]
产甲烷口腔杆菌和人类分子伴侣CCT的抗体反应
Kimito Hirai,Hiroshi Maeda,Kazuhiro Omori et al.
Kimito Hirai et al.
Both group I (HSP60) and group II (CCT) chaperonins are targets of autoantibodies. Autoimmune reactions to HSP60 have been well characterized, while immune reactions to group II chaperonin have not been clarified. Methanobrevibacter oralis ...
Codon optimisation to improve expression of a Mycobacterium avium ssp. paratuberculosis-specific membrane-associated antigen by Lactobacillus salivarius [0.03%]
优化表达Mycobacterium avium ssp. paratuberculosis特异性膜相关抗原的Lactobacillus salivarius菌株的密码子偏好性
Christopher Johnston,Pierre E Douarre,Tewfik Soulimane et al.
Christopher Johnston et al.
Subunit and DNA-based vaccines against Mycobacterium avium ssp. paratuberculosis (MAP) attempt to overcome inherent issues associated with whole-cell formulations. However, these vaccines can be hampered by poor expression of recombinant an...
Resistance to the quorum-quenching compounds brominated furanone C-30 and 5-fluorouracil in Pseudomonas aeruginosa clinical isolates [0.03%]
铜绿假单胞菌临床分离株中存在干扰群体感应分子brominated furanone C-30和5氟尿嘧啶的耐受机制
Rodolfo García-Contreras,Mariano Martínez-Vázquez,Norma Velázquez Guadarrama et al.
Rodolfo García-Contreras et al.
The quorum-quenching compounds brominated furanone C-30 and 5-fluorouracil inhibit the pathogenicity of the Pseudomonas aeruginosa laboratory strains PA01 and PA14; however, there is no report studying the effectiveness of these compounds f...
The long polar fimbriae operon and its flanking regions in bovine Escherichia coli O157:H43 and STEC O136:H12 strains [0.03%]
牛源大肠杆菌O157:H43和STEC O136:H12菌株的长极性纤毛操纵子及其侧翼序列
Domonkos Sváb,Lucia Galli,Balázs Horváth et al.
Domonkos Sváb et al.
Long polar fimbriae (Lpf) are intestinal adhesins and important virulence factors of pathogenic Escherichia coli strains. We cloned and sequenced the lpf2-1 operon (lpf2ABCD) and its flanking regions of an intimin- and Shiga toxin-negative ...
OT-1 mice display minimal upper genital tract pathology following primary intravaginal Chlamydia muridarum infection [0.03%]
Ot-1小鼠在初次阴道感染小鼠沙眼衣原体后上生殖道病变较轻
Srikanth Manam,Bruce J Nicholson,Ashlesh K Murthy
Srikanth Manam
Chlamydia trachomatis is the most common bacterial sexually transmitted disease worldwide and leads to serious pathological sequelae in the upper genital tract (UGT) including pelvic inflammatory disease, ectopic pregnancy, and infertility....
Retnla down-regulation and IL-13-rich environment correlate with inflammation severity in experimental actinomycetoma by Nocardia brasiliensis [0.03%]
Retnla下调和IL-13丰富环境与由巴西诺卡菌引起的实验性Actinomycetoma炎症严重程度相关
Irene Meester,Adrián G Rosas-Taraco,Mario C Salinas-Carmona
Irene Meester
Nocardia brasiliensis (Nb) is a facultative intracellular pathogen that may cause actinomycetoma when immune response is unable to control the pathogenic invasion. We used comparative real-time PCR to evaluate the expression level of molecu...
IgG subclass profiles in normal human sera of antibodies specific to five kinds of microbial antigens [0.03%]
五种微生物抗原特异性抗体IgG亚类的谱系分析
Astrid Hjelholt,Gunna Christiansen,Uffe S Sørensen et al.
Astrid Hjelholt et al.
The levels of subclass-specific immunoglobulin G (IgG) antibodies to five microbial antigens in normal human sera were measured by enzyme-linked immunosorbent assays (ELISA). The aim was to compare the IgG subclass profiles of specific anti...
Lipid IVa incompletely activates MyD88-independent Toll-like receptor 4 signaling in mouse macrophage cell lines [0.03%]
脂质IVa部分激活小鼠巨噬细胞系中的Myd88非依赖性tlr4信号转导路径
Norihiko Ogura,Masashi Muroi,Yuka Sugiura et al.
Norihiko Ogura et al.
We investigated the difference in the effect of synthetic lipid A compounds on MyD88-dependent and -independent Toll-like receptor 4 (TLR4) signaling in mouse macrophage cells. At higher concentrations, Escherichia coli-type hexa-acylated l...
Biofilm formation by Staphylococcus epidermidis on peritoneal dialysis catheters and the effects of extracellular products from Pseudomonas aeruginosa [0.03%]
表皮葡萄球菌在腹膜透析管上的生物被膜形成及绿脓杆菌外源性产物对其的影响
Maria Pihl,Anna Arvidsson,Marie Skepö et al.
Maria Pihl et al.
Biofilm formation by Staphylococcus epidermidis is a cause of infections related to peritoneal dialysis (PD). We have used a PD catheter flow-cell model in combination with confocal scanning laser microscopy and atomic force microscopy to s...