Study on antibacterial effect of halicin (SU3327) against Enterococcus faecalis and Enterococcus faecium [0.03%]
研究苏拉明（SU3327）对粪肠球菌和屎肠球菌抗菌效果的研究
Zubair Hussain,She Pengfei,Li Yimin et al.
Zubair Hussain et al.
Enterococci are important pathogens of nosocomial infections and are increasingly difficult to treat due to their intrinsic and acquired resistance to a range of antibiotics. Therefore, there is an urgent need to develop novel antibacterial...
Involvement of the Noncanonical Polyadenylation Polymerase Cid14 in Fungal Azole Resistance in the Pathogen Cryptococcus neoformans [0.03%]
密码子新型多聚腺苷酸聚合酶Cid14参与病原体新形式隐球菌中耐唑作用
Chenxi Li,Sihui Zhen,Xiaoyu Ma et al.
Chenxi Li et al.
The yeast noncanonical polyadenylation polymerase Cid14 was originally identified from fission yeast and plays a critical role in the TRAMP complex. This protein is a cytoplasmic cofactor and regulator of RNA-degrading exosomes. Cid14 is hi...
S G Negatu,M C Arreguin,K A Jurado et al.
S G Negatu et al.
Viruses and hosts must navigate environments in which each tries to outcompete the other for survival or to coexist within the same spaces. In Lewis Carrol's Through the Looking Glass, the Red Queen tells Alice, "Now, here, you see, it take...
Differential vaccine-induced kinetics of humoral and cellular immune responses in SARS-CoV-2 naive and convalescent health care workers [0.03%]
SARS-CoV-2阴性和康复医护人员的疫苗诱导的体液免疫和细胞免疫反应动力学差异
Wouter Smit,Steven Thijsen,Robert van der Kieft et al.
Wouter Smit et al.
Effective vaccination is a key element in the exit strategy from the current severe acute respiratory syndrome-CoV coronavirus-2 (SARS-CoV-2) pandemic, and may also offer protection against severe disease from future variants of concern. He...
Construction and characterization of the full-length cDNA of an infectious clone of emerging porcine teschovirus-2 [0.03%]
新兴猪博卡病毒2型全长cDNA毒克隆的构建与鉴定
Yuying Li,Shengnan Chen,Yaokai Shi et al.
Yuying Li et al.
Porcine teschovirus (PTV) is a causative agent of polioencephalomyelitis, encephalomyelitis, reproductive disorders and gastrointestinal and respiratory diseases in swine. In the present study, the PTV2 GX/2020 strain was isolated from pig ...
Rupal Rai,Vinayak Singh,Bijina J Mathew et al.
Rupal Rai et al.
Given the emergence and spread of multidrug-resistant and extensively drug-resistant strains of Mycobacterium tuberculosis (Mtb), the world faces the urgency of finding new drugs to combat tuberculosis. Understanding the biochemical/physiol...
Bordetella pertussis outer membrane vesicles as virulence factor vehicles that influence bacterial interaction with macrophages [0.03%]
百日咳博德特氏菌外膜囊泡作为毒力因子载体影响细菌与巨噬细胞的相互作用
Bruno Blancá,Jimena Alvarez Hayes,Kristin Surmann et al.
Bruno Blancá et al.
Gram-negative pathogenic bacteria constitutively shed outer membrane vesicles (OMVs) which play a significant role in the host-pathogen interaction, eventually determining the outcome of the infection. We previously found that Bordetella pe...
Three-dimensional models of the cervicovaginal epithelia to study host-microbiome interactions and sexually transmitted infections [0.03%]
用于研究宿主-微生物组相互作用和性传播感染的宫颈阴道上皮三维模型
Vonetta L Edwards,Elias McComb,Jason P Gleghorn et al.
Vonetta L Edwards et al.
2D cell culture systems have historically provided controlled, reproducible means to analyze host-pathogen interactions observed in the human reproductive tract. Although inexpensive, straightforward, and requiring a very short time commitm...
Impact on quinolone resistance of plasmid-mediated quinolone resistance gene and mutations in quinolone resistance-determining regions in extended spectrum beta lactamase-producing Klebsiella pneumoniae isolated from urinary tract infection patients [0.03%]
携带质粒介导喹诺酮类药物抗性基因及尿路感染产超广谱β内酰胺酶克雷伯菌中喹诺酮类药物抗性决定区域突变对抗喹诺酮类药物的影响
Reo Onishi,Katsumi Shigemura,Kayo Osawa et al.
Reo Onishi et al.
Klebsiella pneumoniae is a typical pathogen in urinary tract infections (UTI), and the emergence of extended spectrum beta-lactamase (ESBL)-producing strains has been frequently reported, accompanied by higher quinolone resistance rates. Th...
Jinlin Chen,Jielite Huang,Zhuoran Liu et al.
Jinlin Chen et al.
The outer membrane proteins (OMPs) of Treponema pallidum subsp. pallidum (T. pallidum), the etiological agent of the sexually transmitted disease syphilis, have long been a hot research topic. Despite many hurdles to studying the pathogen, ...