Roman Cregg,Giovanna Russo,Anthony Gubbay et al.
Roman Cregg et al.
• Individual variability in pain perception and differences in the efficacy of analgesic drugs are complex phenomena and are partly genetically predetermined. • Analgesics act in various ways on the peripheral and central pain pathways an...
Steven A Trim,Carol M Trim
Steven A Trim
Adequate pain control is still a significant challenge and largely unmet medical need in the 21st century. With many small molecules failing to reach required levels of potency and selectivity, drug discovery is once again turning to nature...
Sabu James
Sabu James
Human pain causes untold misery and suffering, with major impact on functioning and resources. Recent advances in genetics have revealed that subtle changes in DNA could partly explain the variation in individual differences in pain. Variou...
Obesity and pain [0.03%]
肥胖与疼痛
Donald Scott McVinnie
Donald Scott McVinnie
Recent reports suggest that almost half of the UK population is expected to be obese by 2030. A number of associations between obesity and chronic pain have been displayed in previous studies, and therefore it can be expected that the prese...
Letter to the Editor [0.03%]
致編輯部的信
Mark Churcher
Mark Churcher
Guest Editorial [0.03%]
客编序言
Mick Serpell
Mick Serpell
Felicia Cox
Felicia Cox
Evidence-based clinical practice guidelines on the management of pain in older people: executive summary [0.03%]
老年患者镇痛管理循证临床实践指南（摘要）
Aza Abdulla,Nicola Adams,Margaret Bone et al.
Aza Abdulla et al.
Is cognitive behavioural therapy for insomnia effective in treating insomnia and pain in individuals with chronic non-malignant pain? [0.03%]
认知行为失眠疗法能否有效改善慢性非恶性疼痛患者的失眠和疼痛症状？
Miqdad H Bohra,Colin A Espie
Miqdad H Bohra
Aim: This paper systematically reviews clinical trials investigating the effectiveness of cognitive behavioural therapy for insomnia and pain in patients with chronic non-malignant pain. ...
Reproducibility of pain manikins: a comparison of paper versus online questionnaires [0.03%]
疼痛人形图的再现性：纸质问卷与在线问卷的比较
Gareth T Jones,Ramona Kyabaggu,Debbi Marais et al.
Gareth T Jones et al.
Background: In epidemiological studies, pain location is often collected by paper questionnaire using blank body manikins, onto which participants shade the location of their pain(s). However, it is unknown how reliable t...