A clinical perspective of obesity, metabolic syndrome and cardiovascular disease [0.03%]
肥胖、代谢综合征和心血管疾病的临床观
Thang S Han,Mike Ej Lean
Thang S Han
The metabolic syndrome is a condition characterized by a special constellation of reversible major risk factors for cardiovascular disease and type 2 diabetes. The main, diagnostic, components are reduced HDL-cholesterol, raised triglycerid...
Expression of the PlA2 allele of glycoprotein IIIa and its impact on platelet function [0.03%]
PlA2等位基因的糖蛋白IIIa表达及其对血小板功能的影响
Christopher N Floyd,Albert Ferro,Timothy D Warner
Christopher N Floyd
Background: The platelet fibrinogen receptor represents the final common pathway of platelet activation, and is formed from two glycoprotein (GP) subunits (GPIIb/IIIa). Carriage of the mutant PlA2 allele of GPIIIa has bee...
Henry Fok,Benyu Jiang,Phil Chowienczyk et al.
Henry Fok et al.
Objectives: Exposure to intravascular microbubbles after diving and during medical procedures alters endothelial function. The aim of this study was to investigate whether a patent foramen ovale altered forearm endothelia...
Longstanding insulin dependent diabetics may not require insulin after the introduction of GLP-1 analogues [0.03%]
长期依赖胰岛素的糖尿病患者在引入GLP-1类似物后可能不再需要胰岛素
Umar Y Raja,Alison E Eastaugh,Mohammed S Younas et al.
Umar Y Raja et al.
Glucagon like peptide (GLP-1) analogues are a relatively novel medication developed primarily for the treatment of type 2 diabetes since 2005. Although GLP-1 analogues have been shown to be more effective in the first few years of diagnosis...
Cardiac rehabilitation with a nurse case manager (GoHeart) across local and regional health authorities improves risk factors, self-care and psychosocial outcomes. A one-year follow-up study [0.03%]
具有护士案主管理的心脏康复（GoHeart）改善危险因素、自我照顾及心理社会结局：为期一年的随访研究
Vibeke Brogaard Hansen,Helle Terkildsen Maindal
Vibeke Brogaard Hansen
Objectives: In Denmark, the local and regional health authorities share responsibility for cardiac rehabilitation (CR). The objective was to assess effectiveness of CR across sectors coordinated by a nurse case manager (N...
Health-related quality of life and long-term morbidity and mortality in patients hospitalised with systolic heart failure [0.03%]
射血分数降低的心力衰竭住院患者的长期死亡率和发病率及健康相关生活质量评估
Jenny Berg,Peter Lindgren,Thomas Kahan et al.
Jenny Berg et al.
Background: Health-related quality of life has been shown to impact prognosis in chronic heart failure, however with limited long-term follow-up. We analysed data spanning 8-12 years to assess the impact of health-related...
Electrocardiogram-based scoring system for predicting secondary pulmonary hypertension: A cross-sectional study [0.03%]
基于心电图的二次肺动脉高压预测评分系统：一项横断面研究
Samir Bipin Pancholy,Ghanshyam Palamaner Subash Shantha,Nimesh Kirit Patel et al.
Samir Bipin Pancholy et al.
Objectives: In this study, we have developed an electrocardiogram-based scoring system to predict secondary pulmonary hypertension. Design: ...
Socioeconomic status does not predict cocaine use among ischemic stroke patients: A nested case-control study [0.03%]
缺血性卒中患者的社会经济地位并不预测可卡因使用：一项病例对照研究
Corey R Fehnel,Alison M Ayres,Natalia S Rost
Corey R Fehnel
Previous studies of cocaine use and stroke have focused on acute effects of cocaine in perceived high-risk populations. We characterized mechanisms and risk factors for cocaine use among ischemic stroke patients from a broad range of socioe...
Asymptomatic carotid stenosis: What we can learn from the next generation of randomized clinical trials [0.03%]
无症状颈动脉狭窄：下一代随机临床试验能给我们带来哪些启示？
Mark N Rubin,Kevin M Barrett,Thomas G Brott et al.
Mark N Rubin et al.
Stroke remains an exceedingly incident and prevalent public health burden across the globe, with an estimated 16 million new strokes per annum and prevalence over 60 million, and extracranial internal carotid artery atherosclerotic disease ...
Aldosterone synthase inhibitors in hypertension: current status and future possibilities [0.03%]
高血压中的醛固酮合酶抑制剂：现状与未来展望
Milan Hargovan,Albert Ferro
Milan Hargovan
The renin-angiotensin aldosterone system is a critical mechanism for controlling blood pressure, and exerts most of its physiological effects through the action of angiotensin II. In addition to increasing blood pressure by increasing vascu...