In-use microbiological assessment of caffeine citrate 10 mg/mL oral solution [0.03%]
咖啡因柠檬酸盐口服溶液的在用微生物监测研究
Julian Smith,Chris Marks
Julian Smith
Objectives: This study was conducted to investigate the microbial contamination of caffeine citrate 10 mg/mL oral solution (CCOS) during a simulated in-use test in a clinical environment. ...
Validation of a procedure to mix homogenous solutions in bags and syringes [0.03%]
用于袋和注射器中混匀均一溶液的方法的验证
Thomann Pauline,Bouchoud Lucie,Bonnabry Pascal
Thomann Pauline
Objectives: It is essential to obtain homogeneous drug mixtures, especially when only a fraction of the prepared dose is to be administered. This study aimed to validate a manual mixing method for guaranteeing homogeneity...
Potassium canrenoate compounding for administration via enteral feeding tubes: a physical and microbiological stability study [0.03%]
坎利酮在肠内营养液中的物理和微生物稳定性的研究
Serena Logrippo,Matteo Sestili,Roberta Ganzetti et al.
Serena Logrippo et al.
Background: Swallowing difficulties are arising in an increasing number of patients, especially in elderly people. When deglutition ability is completely compromised, enteral administration of a drug via feeding tubes is ...
Physical and chemical stability of ceftaroline in an elastomeric infusion device [0.03%]
弹丸式输液装置中ceftriaxone的物理和化学稳定性
Farah Al Madfai,Syed Tabish R Zaidi,Long Chiau Ming et al.
Farah Al Madfai et al.
Background: Severe infections such as endocarditis and osteomyelitis require long-term treatment with parenteral antibiotics and hence prolonged hospitalisation. Continuous infusion of ceftaroline through elastomeric devi...
Stability of prostaglandin E1 solutions stored in polypropylene syringes for continuous intravenous administration to newborns [0.03%]
聚丙烯注射器中前列腺素E1溶液持续静脉输注稳定性的研究
David Palmero,Emilienne Chavan,Markoulina Berger-Gryllaki et al.
David Palmero et al.
Objective: We aimed to monitor the physicochemical stability of prostaglandin E1 (PGE1) 1.5 and 15 µg/mL in 10% dextrose stored in polypropylene syringes. ...
Investigations into the physical and chemical stability of concentrated co-trimoxazole intravenous infusions [0.03%]
大剂量磺胺多辛注射液的物理和化学稳定性的研究
Israa Khaleel,Syed Tabish R Zaidi,Madhur D Shastri et al.
Israa Khaleel et al.
Objectives: High dose of intravenous sulfamethoxazole and trimethoprim (co-trimoxazole) is often used in immunocompromised patients for the treatment of Pneumocystis jiroveci pneumonia. Current manufacturer's dilution rec...
Stability of warfarin sodium flavoured preservative-free oral liquid formulations [0.03%]
调味无防腐口服液体制剂的稳定性研究
Joël Schlatter,Salvatore Cisternino
Joël Schlatter
Objectives: This study was designed to assess the physicochemical stability of warfarin sodium liquid formulations stored at room temperature and under refrigeration. ...
Stability of repackaged dabigatran etexilate capsules in dose administration aids [0.03%]
剂量辅助给药器具中重包装的达比加群酯软胶囊的稳定性
Sherryl G Robertson,Beverley D Glass
Sherryl G Robertson
Objective: This study is aimed at assessing the stability of dabigatran etexilate (Pradaxa) capsules repackaged into a dose administration aid (DAA), in order to inform appropriate storage conditions that ensure quality. ...
Harmanjeet Harmanjeet,Syed Tabish R Zaidi,Long Chiau Ming et al.
Harmanjeet Harmanjeet et al.
Objectives: Voriconazole is the drug of choice for invasive aspergillosis (IA), a leading cause of mortality and morbidity in immunocompromised patients. Prolong intravenous administration of voriconazole is often needed ...
Chemical and microbiological stability, anticoagulant efficacy and toxicity of 35 and 90 mM trisodium citrate solutions stored in plastic syringes [0.03%]
储存在塑料注射器中的35和90mM三钠柠檬酸溶液的化学和微生物稳定性，抗凝血功效和毒性
Paola Milla,Maria Luisa Viterbo,Sabino Mosca et al.
Paola Milla et al.
Background: Trisodium citrate is an interesting alternative to heparin for the prevention of circuit clotting during extracorporeal procedures, but some protocols require non-commercially available citrate concentrations....