Recent European legal developments on second medical uses and dosage regimes [0.03%]
近期欧洲关于第二医疗用途和剂量 regimen的法律发展动态
Fiona Bor,Duncan Curley
Fiona Bor
The curious case of Yasmin(®): when does a generic's label induce doctors to practice a patented method of use? [0.03%]
雅丝明的有趣案例——当通用名药物的说明书诱导医生使用专利给药方法时侵权行为如何认定？
Clark G Sullivan
Clark G Sullivan
John A Christopher
John A Christopher
The orexin neuropeptides bind to two G protein-coupled receptors, orexin-1 and -2. Small-molecule antagonism of the receptors has potential therapeutic utility in a number of areas, most notably insomnia, for which the most advanced dual or...
The A to Z of pharmaceutical cocrystals: a decade of fast-moving new science and patents [0.03%]
药物共晶体的十年快速发展：从科学到专利授权
Örn Almarsson,Matthew L Peterson,Michael Zaworotko
Örn Almarsson
From aspirin to zoledronic acid, pharmaceutical cocrystals emerged in the past decade as a promising new weapon in the arsenal of drug development. Resurgence of interest in multicomponent crystal compositions has led to significant advance...
Glucokinase activators [0.03%]
葡糖激酶激活剂
Kevin J Filipski,Kentaro Futatsugi,Jeffrey A Pfefferkorn et al.
Kevin J Filipski et al.
In this review we highlight recently disclosed progress in the field of small-molecule activators of the human glucokinase enzyme. Several of the reported chemotypes possess structural features that diverge from known leads; some of these m...
Daniel J Buzard,Juerg Lehmann,Sangdon Han et al.
Daniel J Buzard et al.
The increasing incidence of Type II diabetes mellitus worldwide continues to attract the attention and resources of the pharmaceutical industry in the pursuit of more effective therapies for blood glucose control. New approaches that compar...
Supplementary Protection Certificates for medicinal products: where are we now and what challenges lay ahead? [0.03%]
药品补充保护证书现状及未来挑战分析
John Miles
John Miles
In Europe, Supplementary Protection Certificates have been available for human and veterinary medicinal products since 1993. Although certain fundamental issues surrounding them have been resolved, questions still remain about their scope a...
Kimberly Miller,Robert Poolman
Kimberly Miller
Chemical structure searching can be challenging. The most common question in a searcher's mind is, "is my search comprehensive?" What he least wishes to hear from a client is, "why did you miss this?" This article will discuss ways of expan...
Jonathan D M Atkinson,Rachel S Jones
Jonathan D M Atkinson
This article describes a significant change in US patent practice that will see it become more aligned with the patent practice in most if not all of the rest of the world. This change follows recent legislation in the US that has transform...
The transatlantic divide: how divisional and continuing patent application filing practice differs between the USA and Europe [0.03%]
大西洋两岸的差异：美国和欧洲专利申请实践的区别
Emily Nytko-Lutz,Devanand Crease
Emily Nytko-Lutz
In this article we compare patent application 'fragmentation' strategies in the USA and Europe. Recent changes in European law restricting the timeframe in which divisional applications may be filed now make adopting a US-style approach in ...
Comparative Study
Pharmaceutical patent analyst. 2012 Jul;1(3):245-8. DOI:10.4155/ppa.12.36 2012