Regulation of TREM2 on BV2 inflammation through PI3K/AKT/mTOR pathway [0.03%]
TREM2通过PI3K/AKT/mTOR信号通路调节BV2微胶质细胞的炎症反应
Li Li,Qingyou Chen,Yinghui Qin et al.
Li Li et al.
This work sought to determine how lipopolysaccharide (LPS)-induced pro-inflammatory factor production in BV2 microglia was influenced by myeloid cell 2 (TREM2) expressions. LPS (0.1, 1, and 10 µg/mL) induced inflammation in BV2 cells, MTT ...
Diagnosis and treatment of tuberculosis presenting as uveitis based on stochastic simulation in systems biology [0.03%]
基于系统生物学中随机模拟的以虹膜炎形式出现的肺结核的诊疗研究
Li Liu,Yue Gou,Ling Chen et al.
Li Liu et al.
Tuberculous uveitis can be a manifestation of extrapulmonary tuberculosis or an allergic reaction to tuberculosis infection. The clinical signs and symptoms of other uveitis causes are generic, making a false diagnosis simple. We present a ...
CAPN1 is a novel biomaker of patients with AML based on comprehensive analysis [0.03%]
基于综合分析的CAPN1是AML患者的新型生物标志物
Houcai Wang,Ruye Ma,Jianbang Gu et al.
Houcai Wang et al.
Acute myeloid leukemia (AML) is a common hematologic malignancy in adults. Recent studies investigating the potential pathogenesis of AML have significantly advanced our understanding of this disease. While cytogenetics and molecular abnorm...
Evaluating the value of progressive muscle relaxation therapy for patients with lumbar disc herniation after surgery based on a difference-in-differences model [0.03%]
基于差分差分模型下评估经皮腰椎间盘突出症术后患者进行渐进性肌肉放松治疗的价值
Xiaoxin Chen,Guoliang Chen,Yanhong Zhao et al.
Xiaoxin Chen et al.
We evaluate the value of progressive muscle relaxation (PMR) for patients with lumbar disc herniation after surgery based on a difference-in-differences model. A total of 128 patients with lumbar disc herniation who underwent surgery were r...
Clinical effect of laparoscopic cholecystectomy in the treatment of chronic cholecystitis with gallstones [0.03%]
腹腔镜胆囊切除术治疗慢性胆囊炎合并胆结石的临床疗效分析
Shigang Yu,Shucheng Shi,Xuefeng Zhu
Shigang Yu
Chronic cholecystitis is a common disease that causes inflammation in the gallbladder and is usually associated with gallstones. Laparoscopic cholecystectomy has been widely used as a minimally invasive surgical technique to treat this cond...
Analysis of non-targeted serum metabolomics in patients with chronic kidney disease and hyperuricemia [0.03%]
慢性肾脏病合并高尿酸血症患者非目标导向性血清代谢组学分析
Wen-Yu Yang,Jun Wang,Xiao-Han Li et al.
Wen-Yu Yang et al.
Hyperuricemia (HUA) is a common complication of chronic kidney disease (CKD). Conversely, HUA can promote the disease progression of CKD. However, the molecular mechanism of HUA in CKD development remains unclear. In the present study, we a...
CRISPR-mediated iron and folate biofortification in crops: advances and perspectives [0.03%]
基于CRISPR的农作物铁和叶酸营养强化研究进展与展望
Ahamed Khan,Baveesh Pudhuvai,Ankita Shrestha et al.
Ahamed Khan et al.
Micronutrient deficiency conditions, such as anemia, are the most prevalent global health problem due to inadequate iron and folate in dietary sources. Biofortification advancements can propel the rapid amelioration of nutritionally benefic...
Exosomes from adipose-derived stem cells inhibits skin cancer progression via miR-199a-5p/SOX4 [0.03%]
脂肪来源干细胞外泌体通过miR-199a-5p/SOX4抑制皮肤癌进展
Man Liu,Hui Wang,Zijian Liu et al.
Man Liu et al.
Although miR-199a-5p is linked to the development of numerous cancers, its regulatory role in skin cancer is unclear. In this work, the impact of miR-199a-5p produced by adipose-derived stem cells on malignant melanoma skin cancer was inves...
Effects of dapagliflozin on cardiac function indexes and serum MCP-1 levels in patients with Type 2 diabetes mellitus complicated with heart failure [0.03%]
达格列净对2型糖尿病合并心力衰竭患者心脏功能指标及血清MCP-1水平的影响
Xianpei Zhang,Yang Yang,Weizhe Xiao et al.
Xianpei Zhang et al.
Type 2 diabetes mellitus (T2DM) and heart failure (HF) are common in clinic, and they often coexist, triggering poor prognosis of patients and increasing hospitalization rates and mortality. Due to some common pathophysiological mechanisms ...
Comparison of the clinical efficacy of three internal fixation methods in the treatment of Edinburgh type IB fractures of the proximal clavicle [0.03%]
三种内固定方法治疗锁骨近端爱丁堡ⅠB型骨折的临床疗效比较
Chengzhi Ma,Fengxia Miao,Hongxiao Wu et al.
Chengzhi Ma et al.
Clavicle fractures are one of the most common fractures and usually occur in the medial third of the clavicle. The study explored the efficacy of three internal fixation methods to treat Edinburgh IB fractures of the proximal clavicle. 68 p...