Stem introducer designs and surgical technique play a significant role in achieving the optimal implant-cement interface [0.03%]
恰当的椎体成形术通路和手术技术可优化骨水泥-植入股界面的质量
Bernard H van Duren,Kevin Ilo,Sophie Walker et al.
Bernard H van Duren et al.
Aims: Periprosthetic fracture is a major contributor to reoperation with polished taper slip (PTS) cemented stems, which is the most used fixation technique in many countries. A clear cause for this has yet to be establis...
CXCR4 is a response gene for parathyroid hormone which affects osteoblast and osteoclast function in vitro [0.03%]
甲状旁腺素的响应基因CXCR4影响体外成骨细胞和破骨细胞的功能
Beatriz Larraz-Prieto,Louise Hjorth Lind,Jacob Bastholm Olesen et al.
Beatriz Larraz-Prieto et al.
Aims: To investigate the role of CXCR4 in response to teriparatide (TPTD) treatment in osteoblasts and osteoclasts. Methods: Primary mu...
Impact of elevated sclerostin levels on bone resorption : unravelling structural changes and mineral metabolism disruption [0.03%]
高水平抗硬化素对骨吸收的影响：结构变化和矿物质代谢紊乱的解析
María Encarnacion Rodríguez-Ortiz,Juan Miguel Díaz-Tocados,Ana Isabel Torralbo et al.
María Encarnacion Rodríguez-Ortiz et al.
Aims: The physiological function of sclerostin remains unknown. Sclerostin is synthesized by osteocytes and operates by inhibiting the Wnt/β-catenin pathway. Similarly, it is well established that low levels of sclerosti...
Unravelling lumbar disc herniation severity beyond MRI : integrated transcriptomic and metabolomic analyses highlight glycerophospholipid metabolism and inform a machine-learning diagnostic model: a pilot study [0.03%]
揭秘磁共振成像之外的腰椎间盘突出症严重程度：整合转录组学和代谢组学分析揭示甘油磷脂代谢并告知机器学习诊断模型：一项试点研究
Qiaosong Deng,Shiqi Ren,Nan Zhang et al.
Qiaosong Deng et al.
Aims: While MRI serves as a tool for assessing the severity of lumbar disc herniation (LDH), it has been observed that imaging diagnoses do not always align with clinical symptoms in nearly half of patients. The absence o...
The role of palmitoylation modifications in the regulation of bone cell function, bone homeostasis, and osteoporosis [0.03%]
棕榈酰化修饰在骨细胞功能、骨稳态及骨质疏松症中的作用
Ximeng Wang,Yuxuan Zhang,Zhidi Lin et al.
Ximeng Wang et al.
Osteoporosis a is a metabolic bone disease caused by an imbalance in bone homeostasis, which is regulated by osteoblasts and osteoclasts. Protein palmitoylation modification is a post-translational modification that affects protein function...
Growth differentiation factor 15 as a potential diagnostic biomarker for rheumatoid arthritis : a systematic review [0.03%]
生长分化因子15作为类风湿性关节炎潜在诊断生物标志物的系统评价
Xu Liu,Anko E Essien,Wenhao Lu et al.
Xu Liu et al.
Aims: This systematic review aimed to investigate the association between growth differentiation factor 15 (GDF-15) and rheumatoid arthritis (RA) disease activity, explore the differences at the genetic level, and evaluat...
Pulsed Nd:YAG laser therapy accelerates fracture healing in a rat femoral osteotomy model [0.03%]
脉冲Nd:YAG激光治疗加速大鼠股骨截骨愈合模型中的骨折修复
Po-Yen Ko,Che-Chia Hsu,Shih-Yao Chen et al.
Po-Yen Ko et al.
Aims: This study aimed to evaluate the effects of Nd:YAG laser treatment on fracture healing in a rat model. We hypothesized that laser therapy would accelerate healing by stimulating early neovascularization and osteobla...
Decreased femoral fracture load after cephalomedullary nail removal : a biomechanical ex vivo study [0.03%]
髓内钉取出后股骨骨折负荷降低：一项离体生物力学研究
Gilbert M Schwarz,Alexander Synek,Stephanie Huber et al.
Gilbert M Schwarz et al.
Aims: Spontaneous neck fractures are feared complications of cephalomedullary nail removal after successful healing of per- and subtrochanteric fractures. To date, the initial postoperative stability as well as the correc...
Carpaine ameliorates synovial inflammation by promoting p65 degradation and inhibiting the NF-κB signalling pathway [0.03%]
Carpaine通过促进p65蛋白降解和抑制NF-κB信号通路来改善滑膜炎症
Hongbo Zhang,Ziyang Li,Zhicheng Zhang et al.
Hongbo Zhang et al.
Aims: Osteoarthritis (OA) is a chronic and debilitating joint disease. Despite its prevalence, especially in ageing and obese populations, effective treatments targeting the molecular mechanisms of OA are limited. This st...
Challenges and advances in the management of heterotopic ossification in total hip arthroplasty [0.03%]
全髋关节置换术异位骨化的管理挑战与进展
Babar Kayani,Warran Wignadasan,Andreas Fontalis et al.
Babar Kayani et al.