Morpholine as a privileged scaffold for neurodegenerative disease therapeutics [0.03%]
用于神经退行性疾病治疗的吗啉优先支架结构
Saranya Kattil Parmbil,Sunil Kumar,T M Rangarajan et al.
Saranya Kattil Parmbil et al.
Morpholine, a six-membered heterocyclic ring containing oxygen and nitrogen, is increasingly recognized in medicinal chemistry for its diverse pharmacological properties. Morpholine derivatives have shown promise as enzyme inhibitors, neuro...
The pH-dependence of copper(ii/i) reduction potentials in variants of P. aeruginosa azurin with surface histidine variations [0.03%]
铜离子价变标准电势的PH值依赖性及其与绿脓杆菌伴蓝因中膜表面组氨酸变异的关系
Sara Ghodrati Dolatshamloo,Nikta Ghazi,Jeffrey J Warren
Sara Ghodrati Dolatshamloo
Proteins that mediate redox transformations almost always display a degree of pH dependence in their reduction potentials. It is appreciated that surface charges can influence the physical properties of embedded sites. Less clear is the rol...
Balancing high performance with synthesis complexity: one-step hydrothermal growth of self-supported NiCo2Se4 nanoflowers on carbon cloth for advanced asymmetric supercapacitors [0.03%]
高性能与合成复杂性之间的平衡：碳布上自支撑NiCo₂Se₄纳米花的一锅法水热一步生长及其在先进非对称超级电容器中的应用
Junyu Guo,Yawei Hu,Jiasheng Li et al.
Junyu Guo et al.
Bimetallic transition-metal selenides are promising supercapacitor electrodes due to their high theoretical capacitance and rich redox activity. However, achieving high performance often relies on complex multi-step syntheses, limiting prac...
Cembranoids from the cultured soft coral Sinularia sandensis [0.03%]
来自软珊瑚Sinularia sandensis培养物的恩布兰类化合物
Kuei-Hung Lai,Chih-Yuan Liang,You-Ying Chen et al.
Kuei-Hung Lai et al.
This study reports the isolation and characterization of two novel diterpenoids, norcembranoid 10-epi-dehydrogyrosanolide E (1) and cembranoid 8-epi-flexibilisolide G (2), from the cultured soft coral Sinularia sandensis. In addition to the...
Systematic design and optimisation of layer-by-layer nanocomposite coatings on three-dimensional porous scaffolds for enhanced mechanical performance in bone tissue engineering applications [0.03%]
逐层设计和优化纳米复合涂层以改善三维多孔支架的人工骨的机械性能
MohammadAli Sahebalzamani,Helen O McCarthy,Tanya J Levingstone et al.
MohammadAli Sahebalzamani et al.
Structural integrity and interconnected porosity are essential design criteria for bone tissue scaffolds. This study presents the optimisation of electrostatic layer-by-layer (LbL) assembly conditions for nanocomposite multilayer coatings o...
NMR spectroscopic and computational analysis of E/ Z isomerism in imines derived from isatin [0.03%]
异吲哚-1,3-二酮衍生物亚胺的E/Z异构体的核磁共振和计算研究
Andrés Gonzalez-Oñate,Diego Chaparro,Rodolfo Quevedo et al.
Andrés Gonzalez-Oñate et al.
Isatin reacts with primary amines to yield mixtures of E and Z imine stereoisomers. This study provides a detailed structural analysis of selected isatin-derived imines using 1H and 13C NMR spectroscopy, complemented by computational method...
Unusual prenylated phenols with antioxidant and immunosuppressive activities from the edible mushroom Lentinula edodes [0.03%]
具有抗氧化和免疫抑制活性的食用蘑菇鹅膏菌属(Lentinula edodes)中的异戊二烯化酚类化合物
Zhen-Zhu Zhao,Fei Zhang,Qi-Lu Zhao et al.
Zhen-Zhu Zhao et al.
Prenylated phenols, the primary class of mushroom-derived meroterpenoids, exhibit significant structural diversity and biological activities. Two new prenylated phenols (1 and 2), along with four aromatic derivatives, were isolated from the...
Machine learning prediction and calibration of cellulose-based solid-phase extraction performance for pharmaceuticals across aqueous matrices [0.03%]
基于机器学习预测和校准不同水相中纤维素固相萃取性能用于药物分析
Ephriam Akor,Damilare Olorunnisola,Moses O Alfred et al.
Ephriam Akor et al.
Cellulose-based solid-phase extraction has been increasingly proposed for concentrating trace pharmaceuticals from complex waters; however, cross-laboratory transfer remains uncertain because studies vary in matrix chemistry, sorbent functi...
Build-up shielding-factors, and physical & mechanical properties of borosilicate glasses with varied CeO2 contents [0.03%]
不同CeO2含量的硼硅酸盐玻璃能效应因子及物理力学性能研究
H A Abo-Mosallam,Mortaga M Abou-Krisha,Ahmed A Galhoum et al.
H A Abo-Mosallam et al.
Heavy-metal borosilicate glasses of composition 10BaO-10CdO-12PbO-3Al2O3-5SiO2-(Z)CeO2-(60 - Z)B2O3 (where Z = 0.5-4.0 mol%) were synthesized via a melt-quenching technique to systematically evaluate the influence of CeO2 incorporation on t...
Tailoring hydrogenation, thermodynamic properties and oxidation resistance of TiFe alloy by only regulating the stoichiometric ratio of Ti and Fe elements [0.03%]
通过仅调节Ti和Fe元素的化学计量比来调整TiFe合金的加氢性能、热力学性质及抗氧化性
Siqi Xia,Guojie Wu,Dongfang Huang et al.
Siqi Xia et al.
This study systematically investigates the effect of regulating the stoichiometric ratio of Ti and Fe elements on the microstructure, hydrogenation properties, thermodynamics and oxidation resistance of Ti x Fe2-x (x = 1, 1.1, 1.2, 1.3) all...