Exosomal miR-192-5p secreted by bone marrow mesenchymal stem cells inhibits hepatic stellate cell activation and targets PPP2R3A [0.03%]
骨髓间充质干细胞分泌的外泌体miR-192-5p抑制肝星状细胞活化并靶向PPP2R3A
Jie Tan,Mingtao Chen,Meng Liu et al.
Jie Tan et al.
Bone marrow mesenchymal stem cell (BSMC)-derived extracellular vehicles (EVs) have a pivotal therapeutic potential in hepatic fibrosis (HF). Activation of hepatic stellate cells (HSCs) is the key mechanism in HF progression. Downregulation ...
Study of pathological processes of meibomian gland dysfunction by in vitro culture airlifting conditions [0.03%]
体外培养条件下睑板腺功能障碍的病理进程研究
Wenjia Zhang,Shuxian Hu,Hongqin Ke et al.
Wenjia Zhang et al.
Meibomian gland dysfunction (MGD) is a group of disorders linked by functional abnormalities of the meibomian glands. Current studies on MGD pathogenesis focus on meibomian gland cells, providing information on a single cell's response to e...
Perturbation of mitochondrial dynamics links to the aggravation of periodontitis by diabetes [0.03%]
线粒体动态改变可能加重糖尿病患者的牙周炎病理损害
Xinliang Fu,Beilei Liu,Jiyu Sun et al.
Xinliang Fu et al.
Diabetes and periodontitis are prevalent diseases that considerably impact global economy and diabetes is a major risk factor of periodontitis. Mitochondrial dynamic alterations are involved in many diseases including diabetes and this stud...
A customized 3D-printed histological microgrinder for the study of metallic endoprostheses [0.03%]
一种用于金属内植物研究的定制化三维打印组织学微研磨机
Reza Sanaei
Reza Sanaei
Use of histology is the key when evaluation of bone and soft tissue integration of any implanted metallic prosthesis is required. This relies on the ability to prepare very thin sections by grinding down resin embedded samples. Manual grind...
Pranav S Renavikar,Jie Chen,Subodh M Lele
Pranav S Renavikar
Clinicopathological significance of SOX9 and β-catenin expression in pre-neoadjuvant chemotherapy cases of osteosarcoma: molecular and immunohistochemical study [0.03%]
SOX9和β-连环蛋白在骨肉瘤新辅助化疗前表达的意义：分子及免疫组化研究
Sarah Ahmed Hassan,Amal Abdel Aziz Shabaan,Adel Refaat Ahmed et al.
Sarah Ahmed Hassan et al.
The molecular pathogenesis of osteosarcoma (OS), the most frequent primary malignant bone tumor of all age groups, is still obscure. Since multidrug chemotherapeutic regimens were introduced in the 1970s, survival rates have been stationary...
Verhoeff van Gieson staining in laser-irradiated gingival tissues [0.03%]
激光照射下牙龈组织的Verhoeff van Gieson染色法
Joseph A Esposito,Nathan Estrin,Steve A McClain et al.
Joseph A Esposito et al.
There have been several studies on the use of the Verhoeff van Gieson staining method to demonstrate thermal effects on tissues. However, this method has rarely been used for the analysis of periodontal tissues. This study was undertaken to...
Levi Haven,Amanda Bodkin,Sheila L Criswell
Levi Haven
Cat food production is a billion-dollar industry in the United States, with most pet owners trusting pet food companies to provide their pets with complete nutrition. Moist or canned cat food is healthier than dry kibble for cats due to its...
Cell culture: in vitro model system and a promising path to in vivo applications [0.03%]
细胞培养：体外模型系统及其在体内应用中的前景路径
Chongbei Zhao
Chongbei Zhao
Ulinastatin inhibits microglia activation in spinal cord via P2Y12 receptor in a rat neuropathic pain model [0.03%]
乌林酸酯通过P2Y12受体抑制脊髓的小胶质细胞激活治疗大鼠神经病理性疼痛模型
Ying Shi,Huizhong Wen,Jian Cui et al.
Ying Shi et al.
Ulinastatin, a broad spectrum of serine protease inhibitor, has been found to alleviate neuropathic pain (NPP). However, its mechanism is not completely clear. Here, a sciatic nerve ligation rat model and BV2 microglial cells were used to i...