A study of PGP 9.5 immunohistochemical labeling on formalin-fixed paraffin embedded tissues for epidermal nerve fiber density testing [0.03%]
甲醛固定石蜡包埋组织中PGP9.5免疫组化染色表皮神经纤维密度检测的研究
Joseph A Esposito,Camryn J Vader,Joel R Israel et al.
Joseph A Esposito et al.
There have been several methods established for immunohistochemical labeling of the PGP 9.5 antigen in human tissue for the assessment of epidermal nerve fiber density, none of which uses neutral-buffered formalin as the preferred fixative ...
Histogel-based techniques for embedding organoids in paraffin blocks enable high throughput downstream histopathological analyses [0.03%]
基于Histogel的类器官包埋技术实现高效的下游病理分析
Charles Havnar,Loryn Holokai,Ryan Ichikawa et al.
Charles Havnar et al.
Organoids are in vitro tissue models derived from human or animal primary tissues or stem cells that allow for studying three-dimensional (3D) tissue biology, toxicity testing, biomarker evaluation, and assessment of compound efficacy, supp...
A best practices framework for spatial biology studies in drug discovery and development: enabling successful cohort studies using digital spatial profiling [0.03%]
药物发现和开发中空间生物学研究的最佳实践框架：使用数字空间谱分析成功进行队列研究
David Krull,Premi Haynes,Anil Kesarwani et al.
David Krull et al.
The discovery of biomarkers, essential for successful drug development, is often hindered by the limited availability of tissue samples, typically obtained through core needle biopsies. Standard 'omics platforms can consume significant amou...
Sheila Criswell,Brian Gaylord,Christopher R Pitzer
Sheila Criswell
Although many of the structures and organelles of vegetative cells are comparable to those of animal tissues, significant differences between the two kingdoms require modifications in histological techniques for both tissue processing steps...
What will it take for histologists to be recognized under CLIA? [0.03%]
检验医师在临床实验室改进法案（CLIA）中获得认可需要什么？
Elizabeth Chlipala,Tim Morken,Clare Thornton et al.
Elizabeth Chlipala et al.
Comparative analysis of in vivo bio-integration of three hyaluronic acid-based fillers for 26 weeks: a histological study [0.03%]
三种透明质酸基填充剂体内生物相容性26周对比分析：一项组织学研究
Baoji Song,Qiqi Chen
Baoji Song
Stabilized hyaluronic acid (HA), produced through diverse cross-linking technology and formulated as an injectable gel, has found widespread utilization in aesthetic industry. Cross-linked HA essentially constitutes a gel particle compositi...
Comparative Study
Journal of histotechnology. 2024 Dec;47(4):154-165. DOI:10.1080/01478885.2024.2369967 2024
Optimizing immunofluorescent staining of H vessels within an irradiated fracture callus in paraffin-embedded tissue samples [0.03%]
优化石蜡包埋组织样本中放射性骨折愈合组织中的H血管的免疫荧光染色
Nathan T Sheppard,Melissa C Daniel,Noah S Nelson et al.
Nathan T Sheppard et al.
H vessels are an essential link in angiogenic-osteogenic coupling and orchestrate the process of bone healing. H vessels are critically deficient in the setting of radiation-induced fractures, which have been reported to occur in up to 25% ...
Tissue clearing and three-dimensional imaging of intact tissues: a review on FACT protocol [0.03%]
FACT技术组织透明化与三维成像研究进展综述
Zohreh Farrar,Alireza Afshar,Afshin Zare et al.
Zohreh Farrar et al.
FACT is a developed technique for clearing tissues that does not use acrylamide. Since the removal of lipids is crucial for transparency and efficient antibody staining throughout the tissue, especially for microscopy and imaging, it is a h...
Navigating the post-pandemic terrain: lessons in resilience and adaptation [0.03%]
后疫情时代的韧性与适应： Lessons 在韧性与适应中的启示
Chongbei Zhao,Luis A Chiriboga,Elizabeth A Chlipala
Chongbei Zhao
Julie A Renner,Patrick C Riley
Julie A Renner
Hematoxylin and eosin staining can be hazardous, expensive, and prone to error and variability. To circumvent these issues, artificial intelligence/machine learning models such as generative adversarial networks (GANs), are being used to 'v...