Molecules, magic and forgetful fruit flies: the supernatural science of medical gas research [0.03%]
分子、魔法和健忘的果蝇：医学气体研究中的超自然科学
George Mychaskiw nd
George Mychaskiw nd
Medical gas research often involves the study of molecules under extraphysiologic conditions, that is, conditions that do not exist in nature. This "supernatural" nature of medical gas research sometimes produces results that appear to be a...
Normobaric hyperoxia protects the blood brain barrier through inhibiting Nox2 containing NADPH oxidase in ischemic stroke [0.03%]
常压吸氧通过抑制Nox2型NADPH氧化酶保护缺血卒中后的血脑屏障功能
Wenlan Liu,Qingquan Chen,Jie Liu et al.
Wenlan Liu et al.
Normobaric hyperoxia (NBO) has been shown to be neuro- and vaso-protective during ischemic stroke. However, the underlying mechanisms remain to be fully elucidated. Activation of NADPH oxidase critically contributes to ischemic brain damage...
Lei Huang,Andre Obenaus
Lei Huang
Traumatic brain injury (TBI) is a major public health issue. The complexity of TBI has precluded the use of effective therapies. Hyperbaric oxygen therapy (HBOT) has been shown to be neuroprotective in multiple neurological disorders, but i...
Early cognitive function, recovery and well-being after sevoflurane and xenon anaesthesia in the elderly: a double-blinded randomized controlled trial [0.03%]
异氟醚与氙气麻醉对老年人早期认知功能、恢复及预后的比较：一项双盲随机对照试验
Jan Cremer,Christian Stoppe,Astrid V Fahlenkamp et al.
Jan Cremer et al.
Background: The postoperative cognitive function is impaired in elderly patients after general anaesthesia. The fast recovery after xenon anaesthesia was hypothesized to be advantageous in this scenario. We compared early...
ACS6, a Hydrogen sulfide-donating derivative of sildenafil, inhibits homocysteine-induced apoptosis by preservation of mitochondrial function [0.03%]
新型供氢化硫衍生物ACS6通过维持线粒体功能抑制高半胱氨酸致血管内皮细胞凋亡
Xiao-Qing Tang,Rong-Qian Chen,Yan-Kai Ren et al.
Xiao-Qing Tang et al.
Background: The hydrogen sulfide-releasing sildenafil, ACS6, has been demonstrated to inhibit superoxide formation through donating hydrogen sulfide (H2S). We have found that H2S antagonizes homocysteine-induced oxidative...
Moderately delayed post-insult treatment with normobaric hyperoxia reduces excitotoxin-induced neuronal degeneration but increases ischemia-induced brain damage [0.03%]
中度延迟的常压氧疗加重缺血性脑损伤但可减轻兴奋毒性神经元退变
Benoit Haelewyn,Laurent Chazalviel,Olivier Nicole et al.
Benoit Haelewyn et al.
Background: The use and benefits of normobaric oxygen (NBO) in patients suffering acute ischemic stroke is still controversial. Results: ...
Carbon monoxide inhibits Fas activating antibody-induced apoptosis in endothelial cells [0.03%]
一氧化碳抑制内皮细胞Fas活化抗体诱导的细胞凋亡
Xue Wang,Yong Wang,Seon-Jin Lee et al.
Xue Wang et al.
Background: The extrinsic apoptotic pathway initiates when a death ligand, such as the Fas ligand, interacts with its cell surface receptor (ie., Fas/CD95), forming a death-inducing signaling complex (DISC). The Fas-depen...
Jan M Eckermann,Wanqiu Chen,Vikram Jadhav et al.
Jan M Eckermann et al.
Background: Neurosurgical operations cause unavoidable damage to healthy brain tissues. Direct surgical injury as well as surgically induced oxidative stress contributes to the subsequent formation of brain edema. Therefo...
The pacific chapter annual meeting of the undersea & hyperbaric medical society [0.03%]
美国 undersea & hyperbaric 医学协会太平洋分会年会
Robert P Ostrowski,Takkin Lo,John H Zhang
Robert P Ostrowski
The following is the summary report on the UHMS Pacific Chapter Annual Meeting held in Long Beach in October 2010. The conference provided the latest updates on scientific, technical and organizational aspects of Hyperbaric and Diving Medic...
Oxygen/ozone as a medical gas mixture. A critical evaluation of the various methods clarifies positive and negative aspects [0.03%]
氧/臭氧混合气体作为医疗用气的研究及其各种方法的利弊评估
Velio Bocci,Iacopo Zanardi,Valter Travagli
Velio Bocci
Besides oxygen, several other gases such as NO, CO, H2, H2S, Xe and O3 have come to age over the past few years. With regards to O3, its mechanisms of action in medicine have been clarified during the last two decades so that now a comprehe...