Hyperbaric oxygen in chronic traumatic brain injury: oxygen, pressure, and gene therapy [0.03%]
高压氧在慢性创伤性脑损伤治疗中的应用：氧气、压力和基因疗法
Paul G Harch
Paul G Harch
Hyperbaric oxygen therapy is a treatment for wounds in any location and of any duration that has been misunderstood for 353 years. Since 2008 it has been applied to the persistent post-concussion syndrome of mild traumatic brain injury by c...
Pharmacokinetic analysis of the chronic administration of the inert gases Xe and Ar using a physiological based model [0.03%]
基于生理的模型在慢性惰性气体氙和氩药代动力学分析中的应用
Ira Katz,Jacqueline Murdock,Marc Palgen et al.
Ira Katz et al.
Background: New gas therapies using inert gases such as xenon and argon are being studied, which would require chronically administered repeating doses. The pharmacokinetics of this type of administration has not been add...
Hyperbaric oxygen therapy ameliorates TNBS-induced acute distal colitis in rats [0.03%]
高压氧治疗改善TNBS诱导的大鼠急性远端结肠炎
Rogério S Parra,Alexandre H Lopes,Eleonora U Carreira et al.
Rogério S Parra et al.
Background: This study investigated the therapeutic effects of hyperbaric oxygen in experimental acute distal colitis focusing on its effect on the production of pro-inflammatory cytokines, nitric oxide and hypoxia-induci...
Defining the minimally effective dose and schedule for parenteral hydrogen sulfide: long-term benefits in a rat model of hindlimb ischemia [0.03%]
定义用于治疗缺血后长期血管再生的最低有效剂量和给药次数：以大鼠后肢缺血模型为例
John William Langston,Christopher F Toombs
John William Langston
Background: Peripheral arterial disease (PAD) affects millions of Americans and leads to critical limb ischemia (CLI) in the most severe cases. Investigators have demonstrated the utility of hydrogen sulfide for restoring...
Hyperbaric oxygen therapy applied research in traumatic brain injury: from mechanisms to clinical investigation [0.03%]
高压氧治疗在创伤性脑损伤应用研究中的机制和临床探讨
Yang Wang,Dongdong Chen,Gang Chen
Yang Wang
Traumatic brain injury (TBI) is the leading cause of mortality and morbidity for millions of young people and military personnel around the world every year. Regardless of severity, neurological dysfunction is a sequela of TBI. Although man...
A review of experimental studies of hydrogen as a new therapeutic agent in emergency and critical care medicine [0.03%]
氢气作为急危重急救新治疗手段的实验研究进展评述
Meihua Shen,Hongying Zhang,Congjun Yu et al.
Meihua Shen et al.
Hydrogen is the most abundant chemical element in the Universe, but is seldom regarded as a therapeutic agent. Recent evidence has shown that hydrogen is a potent antioxidative, antiapoptotic and anti-inflammatory agent and so may have pote...
The H2S-releasing naproxen derivative, ATB-346, inhibits alveolar bone loss and inflammation in rats with ligature-induced periodontitis [0.03%]
新型含硫前药ATB-346对线扎型大鼠牙周炎的骨破坏与炎症的抑制作用及机制研究
Bruno Schneider Herrera,Leila Santana Coimbra,Agatha Ribeiro da Silva et al.
Bruno Schneider Herrera et al.
Background: In experimental periodontitis, non-steroidal antiinflammatory drugs (NSAIDs) effectively inhibit the resultant alveolar bone loss. However, their deleterious gastric effects, observed in both animals and human...
Ling Yan,Ting Liang,Oumei Cheng
Ling Yan
Hyperbaric oxygen therapy (HBOT) is defined as a treatment in which a patient intermittently breathes 100% oxygen while the treatment chamber is pressurized to a pressure greater than sea level (1.0 atmosphere absolute, ATA). In China, for ...
Expression analysis following argon treatment in an in vivo model of transient middle cerebral artery occlusion in rats [0.03%]
氩气处理大鼠短暂性中动脉闭塞模型的表达谱分析研究
Astrid V Fahlenkamp,Mark Coburn,Antonio de Prada et al.
Astrid V Fahlenkamp et al.
Background: Argon treatment following experimental neurotrauma has been found neuroprotective in an array of in vivo and in vitro models. The inherent cellular and molecular mechanisms are still unknown. We seeked to shed...
A systematic review of neuroprotective strategies after cardiac arrest: from bench to bedside (part II-comprehensive protection) [0.03%]
心脏停搏后的神经保护策略系统评价：从基础到临床（第2部分综合保护）
Lei Huang,Patricia M Applegate,Jason W Gatling et al.
Lei Huang et al.
Neurocognitive deficits remain a significant source of morbidity in survivors of cardiac arrest. We conducted a literature review of treatment protocols designed to evaluate neurologic outcome and survival following global cerebral ischemia...