Wen-Cao Liu,Xin-Chun Jin
Wen-Cao Liu
The presence of a salvageable penumbra, a region of ischemic brain tissue with sufficient energy for short-term survival, has been widely agreed as the premise for thrombolytic therapy with tissue plasminogen activator (tPA), which remains ...
Paradigms and mechanisms of inhalational anesthetics mediated neuroprotection against cerebral ischemic stroke [0.03%]
吸入性麻醉药介导的缺血性脑卒中的神经保护作用机制研究
Hailian Wang,Peiying Li,Na Xu et al.
Hailian Wang et al.
Cerebral ischemic stroke is a leading cause of serious long-term disability and cognitive dysfunction. The high mortality and disability of cerebral ischemic stroke is urging the health providers, including anesthesiologists and other perio...
Neuroprotective effect of hyperbaric oxygen therapy in a juvenile rat model of repetitive mild traumatic brain injury [0.03%]
重复性轻度创伤性脑损伤的青春期大鼠模型中高压氧治疗的神经保护作用
Lei Huang,Andre Obenaus,Mary Hamer et al.
Lei Huang et al.
Repetitive mild traumatic brain injury (rmTBI) is an important medical concern for adolescent athletes that can lead to long-term disabilities. Multiple mild injuries may exacerbate tissue damage resulting in cumulative brain injury and poo...
Peripheral surgical wounding may induce cognitive impairment through interlukin-6-dependent mechanisms in aged mice [0.03%]
外周手术创伤可通过依赖细胞因子白介素-6的机制诱导年老小鼠认知障碍
Yuanlin Dong,Zhipeng Xu,Lining Huang et al.
Yuanlin Dong et al.
Post-operative cognitive dysfunction (POCD) is associated with morbidity, mortality and increased cost of medical care. However, the neuropathogenesis and targeted interventions of POCD remain largely to be determined. We have found that th...
Successful treatment with hydrogen rich water in a case of chronic graft-versus-host-disease [0.03%]
氢气治疗慢性移植物抗宿主病一例报告
Li-Ren Qian,Jian-Liang Shen
Li-Ren Qian
The incidence of chronic graft-versus-host-disease is rising year by year, which has become the leading cause of non-transplantation related death and has become the most difficult complication of allogeneic hematopoietic stem cell transpla...
Hypoxia therapy--a new hope for the treatment of mitochondrial dysfunctions [0.03%]
低氧疗法——线粒体功能障碍治疗的新希望
Jun-Long Huang,Anatol Manaenko,Zhou-Heng Ye et al.
Jun-Long Huang et al.
Mitochondrial dysfunctions are characteristic features of numerous diseases and play a critical role in disease pathogenesis. Despite intensive research in this area, there are no approved therapies that directly target mitochondria. Recent...
Effects of normobaric versus hyperbaric oxygen on cell injury induced by oxygen and glucose deprivation in acute brain slices [0.03%]
常压氧与高压氧对急性脑切片缺糖缺氧损伤的影响
Laurent Chazalviel,Jean-Eric Blatteau,Nicolas Vallée et al.
Laurent Chazalviel et al.
Normobaric oxygen (NBO) and hyperbaric oxygen (HBO) are emerging as a possible co-treatment of acute ischemic stroke. Both have been shown to reduce infarct volume, to improve neurologic outcome, to promote endogenous tissue plasminogen act...
Zhou-Heng Ye,Xue-Jun Sun
Zhou-Heng Ye
The production of high dose hydrogen gas by the AMS-H-01 for treatment of disease [0.03%]
利用AMS-H-01产生高浓度氢气治疗疾病
Richard Camara,Lei Huang,John H Zhang
Richard Camara
Hydrogen gas is a new and promising treatment option for a variety of diseases including stroke. Here, we introduce the AMS-H-01, a medically approved machine capable of safely producing ~66% hydrogen gas. Furthermore, we propose the signif...
Luo-Kun Xie,Shao-Hua Yang
Luo-Kun Xie
Globins are globular proteins for either transport or storage of oxygen which are critical for cellular metabolism. Four globins have been identified in rodent and human brains. Among them, neuroglobin, cytoglobin and hemoglobin chains are ...