The pseudopeptide HB-19 binds to cell surface nucleolin and inhibits angiogenesis [0.03%]
拟肽HB-19与细胞表面核蛋白核糖体磷蛋白A结合并抑制血管生成
Charalampos Birmpas,Jean Paul Briand,Josẻ Courty et al.
Charalampos Birmpas et al.
Background: Nucleolin is a protein over-expressed on the surface of tumor and endothelial cells. Recent studies have underlined the involvement of cell surface nucleolin in tumor growth and angiogenesis. This cell surface...
Citicoline induces angiogenesis improving survival of vascular/human brain microvessel endothelial cells through pathways involving ERK1/2 and insulin receptor substrate-1 [0.03%]
胞苷酸二钠改善血管及人脑微血管内皮细胞存活诱导生成新生血管作用机制研究
Jerzy Krupinski,Manal Abudawood,Sabine Matou-Nasri et al.
Jerzy Krupinski et al.
Background: Citicoline is one of the neuroprotective agents that have been used as a therapy in stroke patients. There is limited published data describing the mechanisms through which it acts. ...
CM-AVM syndrome in a neonate: case report and treatment with a novel flow reduction strategy [0.03%]
新生儿CM-AVM综合征的病例报告及应用新型血流减少策略治疗
Gerald G Behr,Leonardo Liberman,Jocelyn Compton et al.
Gerald G Behr et al.
Mutations in the RASA-1 gene underlie several related disorders of vasculogenesis. Capillary malformation-arteriovenous malformation (CM-AVM) is one such entity and was recently encountered in a neonate who demonstrated its clinical and rad...
Case Reports
Vascular cell. 2012 Nov 20;4(1):19. DOI:10.1186/2045-824X-4-19 2012
Regulation of endothelial permeability and transendothelial migration of cancer cells by tropomyosin-1 phosphorylation [0.03%]
肌动蛋白调节蛋白基质金属肽酶处理的肿瘤细胞转移及其对血管通透性的影响
Bryan Simoneau,François Houle,Jacques Huot
Bryan Simoneau
Background: Loss of endothelial cell integrity and selective permeability barrier is an early event in the sequence of oxidant-mediated injury and may result in atherosclerosis, hypertension and facilitation of transendot...
"Large eaters" meet blood vessels: a new thematic series on macrophages and angiogenesis [0.03%]
“大型吃货”与血管：“巨噬细胞和新生血管”主题系列论文集
Jan Kitajewski
Jan Kitajewski
Vascular Cell has launched a new series on macrophages and angiogenesis, a quickly evolving field critical to blood and lymphatic vessels during development, inflammation and tumorigenesis.
Temporal expression analysis of angiogenesis-related genes in brain development [0.03%]
脑发育中与血管生成相关基因的时间表达分析
Abdulkadir Ozkan,Atilla Biçer,Timuçin Avşar et al.
Abdulkadir Ozkan et al.
Background: The current knowledge on molecular pathogenesis of cerebral vascular malformations (CVM), which are believed to arise during development, is very limited. To unravel the molecular mechanisms involved in CVMs, ...
Deciphering the roles of macrophages in developmental and inflammation stimulated lymphangiogenesis [0.03%]
巨噬细胞在发育和炎症刺激的淋巴管生成中的作用机制研究
Natasha L Harvey,Emma J Gordon
Natasha L Harvey
Lymphatic vessels share an intimate relationship with hematopoietic cells that commences during embryogenesis and continues throughout life. Lymphatic vessels provide a key conduit for immune cell trafficking during immune surveillance and ...
Michael C Schmid,Judith A Varner
Michael C Schmid
Bone marrow derived myeloid cells progressively accumulate in tumors, where they establish an inflammatory microenvironment that is favorable for tumor growth and spread. These cells are comprised primarily of monocytic and granulocytic mye...
Andrew C Newman,Christopher C W Hughes
Andrew C Newman
Macrophages regulate many developmental and pathological processes in both embryonic and adult tissues, and recent studies have shown a significant role in angiogenesis. Similarly, Wnt signaling is fundamental to tissue morphogenesis and al...
Endothelial cell senescence is associated with disrupted cell-cell junctions and increased monolayer permeability [0.03%]
内皮细胞衰老与细胞间连接破坏及单层渗透性增加有关
Vincent J D Krouwer,Liesbeth H P Hekking,Miriam Langelaar-Makkinje et al.
Vincent J D Krouwer et al.
Background: Cellular senescence is associated with cellular dysfunction and has been shown to occur in vivo in age-related cardiovascular diseases such as atherosclerosis. Atherogenesis is accompanied by intimal accumulat...