Anchalee Senavonge,Ruth P Cusack,Christiane E Whetstone et al.
Anchalee Senavonge et al.
Evaluation of Diagnosis, Cross-Reactivity, and Risk Factors in Pediatric Patients With Macrolide Allergy [0.03%]
儿童大环内酯类药物过敏的诊断、交叉反应及危险因素的评估
Güler Yıldırım,Merve Karaca Şahin,Nilay Çalışkan et al.
Güler Yıldırım et al.
Background: Macrolide antibiotics are generally considered safe in children, but allergic reactions can still occur. This study aims to evaluate the sensitivity and specificity of intradermal test (IDT) used to detect mac...
Implementation of Rapid Drug Desensitization in Antineoplastic Drug Therapy in Denmark Using One-Bag Protocols [0.03%]
丹麦使用一次性包 protocol 实施抗肿瘤药物的快速脱敏疗法
Trine Holm Rasmussen,Charlotte Gotthard Mortz,Per Pfeiffer et al.
Trine Holm Rasmussen et al.
Background: Rapid drug desensitization (RDD) is the cornerstone of managing patients with immediate drug hypersensitivity reactions (IDHR) to antineoplastic drugs in Southern Europe and the United States. As the first in ...
Benralizumab Depletes IL-5Rα-Bearing Cells in Skin Lesions of Patients With Atopic Dermatitis [0.03%]
Benralizumab耗竭异位性皮肤炎患者皮肤病灶中的IL-5Rα阳性细胞
Christiane E Whetstone,Ruth P Cusack,Emma L Price et al.
Christiane E Whetstone et al.
Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by tissue eosinophilia and itch. We evaluated the effect of eosinophil depletion with benralizumab on markers of inflammation in the ...
Can Synthetic Data Allow for Smaller Sample Sizes in Chronic Urticaria Research? [0.03%]
合成数据能否减少慢性荨麻疹研究中的样本量？
Annika Gutsche,Pascale Salameh,Samad S Jahandideh et al.
Annika Gutsche et al.
Background: Robust data are essential for clinical and epidemiological research, yet in chronic spontaneous urticaria (CSU), certain patient groups, such as the elderly or comorbid patients, are often underrepresented. In...
Optimizing Adrenaline Administration in Anaphylaxis: Clinical Practice Considerations and Safety Insights [0.03%]
过敏反应肾上腺素使用的优化：临床实践和安全启示
Motohiro Ebisawa,Antonella Muraro,Margitta Worm et al.
Motohiro Ebisawa et al.
Background: Anaphylaxis is an acute, severe, and potentially fatal reaction marked by the fast onset of symptoms and organ involvement that may lead to death from vascular collapse or airway obstruction. Despite adrenalin...
Association of ZNF608 Polymorphisms With House Dust Mite-Induced Allergic Rhinitis [0.03%]
ZNF608多态性与粉尘螨诱导的过敏性鼻炎的相关性研究
Huiqin Li,Fang Gao,Xuyan Liu et al.
Huiqin Li et al.
Background: Genetic factors contribute essentially to the pathophysiology of house dust mite (HDM)-induced allergic rhinitis. Previous studies mainly focused on the biological pathogenesis, but the heritability remains po...
Challenges of Transitional Care for Young Allergy and Asthma Patients From Healthcare Professionals' Perspectives [0.03%]
从医疗保健专业人员的角度看年轻过敏和哮喘患者过渡期照护的挑战
Maria Ödling,Birgitta Lagercrantz,Susanne Lundin et al.
Maria Ödling et al.
Objective: Evidence-based guidelines for transitional care of adolescents and young adults with allergy and asthma have been published, but shortcomings in the transition process have been identified. This study's aim was...
Genetic and Environmental Contributions to Serological Biomarkers of Extracellular Matrix Remodeling in Asthma: A Twin Study [0.03%]
遗传和环境因素对哮喘患者细胞外基质重塑血清生物标志物的贡献：一项双胞胎研究
Matej Andelic,Vibeke Backer,Kirsten Ohm Kyvik et al.
Matej Andelic et al.
Background: Asthma is characterized by airway obstruction driven by chronic inflammation, leading to extracellular matrix (ECM) remodeling. This involves ECM alterations, including increased collagen deposition and elasto...
Lung Acetate Levels Decline in Correlation With Increased Type 2 Allergic Markers in a House Dust Mite Allergic Mouse Model [0.03%]
屋尘螨过敏小鼠模型中肺乙酸水平与2型过敏标志物的增加呈负相关
Roos E M Verstegen,Rolf W Sparidans,Atanaska I Kostadinova et al.
Roos E M Verstegen et al.
Aims: Microbial dysbiosis is an important feature in allergic asthma. Short-chain fatty acids (SCFA) produced by the intestinal microbiome play a role in the gut-lung axis. Little is known about how the gut SCFA levels re...