Distinct Phenotypes of Peripheral Innate Lymphoid Cells and T Cells in Type 2 and Non-Type 2 Asthma [0.03%]
2型和非2型哮喘外周固有淋巴样细胞和T细胞的不同表型
Maura M Kere,Sophia Björkander,Simon Kebede Merid et al.
Maura M Kere et al.
Background: Investigation of T cell and innate lymphoid cell (ILC) subsets in type 2 (T2) and non-type 2 (non-T2) asthma are needed to elucidate disease mechanisms. In this study, we aimed to identify ILC, CD4+, and CD8+ ...
The Role of Air Pollution in the Pathogenesis of Atopic Dermatitis, With a Focus on Oxidative Stress [0.03%]
空气污染在特应性皮炎发病机制中的作用——以氧化应激为重点
Chen-Xi Liu,Li Li,Yue-Ping Zeng
Chen-Xi Liu
Background: Atopic Dermatitis (AD) is a chronic inflammatory skin condition characterized by intensely itchy eczematous lesions and dryness. Recent epidemiological studies have indicated a notable increase in the prevalen...
Persistent Off-Season Dysregulation of Memory B Cell Subsets in Allergic Rhinitis [0.03%]
过敏性鼻炎患者记忆B细胞亚群的持续性失调
Maryam Jafari,Eric Hjalmarsson,Laila Hellkvist et al.
Maryam Jafari et al.
Introduction: Allergic rhinitis (AR) is a common allergic airway disease. Although B cells play essential roles in AR pathogenesis, their subset distribution outside the allergen exposure period remains poorly characteriz...
Sputum Eosinophil and Macrophage Changes After Aspirin Challenge in Patients With Nonsteroidal Anti-Inflammatory Drug-Exacerbated Respiratory Disease [0.03%]
非甾体抗炎药诱发性呼吸系统疾病患者服用阿司匹林后的痰液中嗜酸性粒细胞及巨噬细胞的变化
Gabriela Trąd-Wójcik,Piotr Szatkowski,Adam Ćmiel et al.
Gabriela Trąd-Wójcik et al.
Background: Induced sputum cell count is crucial for assessing airway inflammatory phenotypes. This study investigated how aspirin-induced bronchospasm affects sputum cell counts in patients with nonsteroidal anti-inflamm...
Innovative Strategies to Reduce Exposure and Expression of the Major Cat Allergen Fel d 1 [0.03%]
降低主要猫过敏原Fel d 1暴露和表达的创新策略
Simone Colosimo,Cristiana Indolfi,Vittoria Frattolillo et al.
Simone Colosimo et al.
Background: Fel d 1, the primary allergen produced by cats, is a glycoprotein found mainly in their salivary and sebaceous glands. Due to its small size and stability, it easily becomes airborne and adheres to surfaces, p...
Early Changes in House Dust Mite Component Specific Immunoglobulin Levels Predict the One-Year Efficacy of Allergen Immunotherapy in Patients With Allergic Rhinitis [0.03%]
屋尘螨各成分特异性Ig水平的早期变化可预测过敏性鼻炎患者一年的免疫治疗效果
Shuying Li,Yue Ma,Jiaying Li et al.
Shuying Li et al.
Background: The efficacy of subcutaneous immunotherapy (SCIT) in allergic rhinitis (AR) patients varies. Component-resolved diagnostics (CRD) may serve as a useful tool to predict therapeutic responses. ...
Subcutaneous Allergen-Specific Immunotherapy for Allergic Rhinitis: Divergent IgA Responses in Nasal Mucosa and Blood With Validation of B Cell Class-Switching in Lymph Nodes and Blood [0.03%]
过敏性鼻炎皮下特异性免疫治疗：鼻粘膜和血液中IgA反应的差异以及淋巴结和血液中B细胞类别转换的验证
Maryam Jafari,Marianne Petro,Eirini Paziou et al.
Maryam Jafari et al.
Background: Subcutaneous immunotherapy (SCIT) has been a cornerstone treatment for allergic rhinitis (AR) for over 50 years, consistently demonstrating symptom reduction and modulation of immune responses. Despite this, t...
Characterization of Chronic Rhinosinusitis Patients Based on Markers of Type 2 Inflammation: Findings From the European CRS Outcome Registry (CHRINOSOR) [0.03%]
基于2型炎症标志物的慢性鼻窦炎患者特征分析：欧洲慢性鼻窦炎结局登记（CHRINOSOR）结果
Carlo Cavaliere,Sven F Seys,Joost de Kinderen et al.
Carlo Cavaliere et al.
Background: Primary chronic rhinosinusitis (CRS) can be classified based on the sinuses involved and the dominant endotype of the mucosal inflammation. Since the introduction of type 2 targeted biologics as treatment opti...
The usefulness of the basophil activation test for monitoring the effectiveness of wasp venom immunotherapy in different age groups [0.03%]
不同年龄段监测黄蜂毒免疫治疗有效性的嗜碱性粒细胞活化检测的价值
Andrzej Bozek,Martyna Miodonska,Aleksandra Mitka et al.
Andrzej Bozek et al.
Potential Protective Role of Galectin-3 in Airway Dilatation in Obstructive Airway Diseases [0.03%]
Galectin-3在阻塞性气道疾病中对气道扩张的潜在保护作用
Mariko Kogo,Hisako Matsumoto,Naoya Tanabe et al.
Mariko Kogo et al.