Which Is the Best Biologic for Nasal Polyps: An Updated Network Meta-Analysis [0.03%]
鼻息肉最佳生物制剂的网状meta分析（更新版）
Xi Xu,Jinting Lin,Minting Luo et al.
Xi Xu et al.
Background: Direct comparative efficacy data for biologics in chronic rhinosinusitis with nasal polyps (CRSwNP) remain limited, particularly for novel agents like tezepelumab, underscoring the need to identify optimal the...
ST2+ Erythroid Progenitors Suppress Allergic Asthma by Scavenging IL-33 in Young Mice [0.03%]
ST2+红系祖细胞通过清除白介素-33抑制小鼠过敏性哮喘
Chang Li,Jie Liu,Xiaoshi Li et al.
Chang Li et al.
Background: Although IL-33/ST2 signaling has been implicated in adult asthma, its contribution to early-onset allergic asthma remains poorly understood. Here, we examined the postnatal dynamics of IL-33 and its regulation...
Digital Innovation in Asthma Management in Italy: Results From the "Confronting Asthma Survey" [0.03%]
意大利哮喘管理的数字化创新：“正视哮喘调查”的结果
Manuela Latorre,Pierluigi Paggiaro,Cristina Cardini et al.
Manuela Latorre et al.
Background: The rapid digital transformation has significantly impacted healthcare, particularly through eHealth solutions that offer great potential for managing chronic respiratory conditions such as asthma. This study ...
A Novel Cell Culture System to Improve MRGPRX2 Research in Human Skin Mast Cells [0.03%]
一种新型细胞培养系统可改善人皮肤肥大细胞中MRGPRX2的研究
Zhuoran Li,Jean Schneikert,Anja Wegner et al.
Zhuoran Li et al.
Background: MRGPRX2, a receptor central to mast cell (MC) activation and related skin diseases, is selectively expressed in skin MCs but downregulated during culture by stem cell factor (SCF) and interleukin-4 (IL-4). ...
Next Generation Sequencing of Genes With Epigenetic Alterations in Mastocytosis [0.03%]
组蛋白变异的基因在 mastocytosis 中的下一代序列测定结果
Aleksandra Górska,Thierry van De Wetering,Marta Sobalska-Kwapis et al.
Aleksandra Górska et al.
Aim: Mastocytosis is a neoplastic disease of the bone marrow associated with the risk of frequent and severe allergic reactions. However, the genetic predisposition is not fully understood, and the crucial element in path...
Digital Monitoring of Symptoms and Lung Function During Birch Pollen Season in Pediatric Patients [0.03%]
儿童患者在桦树花粉季节的数字症状和肺功能监测
Tiina Helena Tanninen,Paula Hannele Reiterä,Annika Saarto et al.
Tiina Helena Tanninen et al.
Background: Mobile health (mHealth) applications for asthma and allergic rhinitis (AR) may guide patients in following medication use, symptoms, and lung function supporting self-management. ...
Improving Diagnostic Accuracy in Respiratory Allergy: Monocentric Reevaluation of the GA2LEN Panel in Germany [0.03%]
提高呼吸系统过敏诊断的准确性：德国对GA2LEN检测板的单中心再评价研究
Caroline Beutner,Christian Meyer,Moritz Maximilian Hollstein et al.
Caroline Beutner et al.
Background: European guidelines recommend using a standardized baseline series of skin prick test (SPT) allergens for the diagnosis of airway allergies. In addition, local adaptation and/or extension of test panels accord...
Identifying Genetic Variants in Patients With Cefaclor-Induced Anaphylaxis Using Human Leukocyte Antigen Typing and Whole-Exome Sequencing [0.03%]
采用人类白细胞抗原分型和外显子组测序鉴定头孢克洛致严重过敏反应的遗传变异
Sung-Ryeol Kim,Da Eun Lee,Hyun Young Jung et al.
Sung-Ryeol Kim et al.
Background: Cefaclor is a commonly prescribed β-lactam antibiotic and a known major cause of immediate-type drug hypersensitivity in Korea. However, its genetic risk factors remain poorly understood. We aimed to identify...
Food Sensitization Is Associated With Atopic Dermatitis Severity, Gut-Derived Metabolites and Leaky Gut in Adults [0.03%]
食物敏感与成人特应性皮炎的严重程度、肠道来源代谢物和肠道渗漏有关
Leszek Blicharz,Emilia Samborowska,Radosław Zagożdżon et al.
Leszek Blicharz et al.
Background: Gut microbiome dysbiosis may cause metabolic dysregulation and intestinal barrier impairment. The latter are hypothesized to provoke food allergy and aggravate cutaneous inflammation. Our objective was to dete...
Reference Values and Determinants of Fractional Exhaled Nitric Oxide in a Representative Adult Population in Western Sweden [0.03%]
西瑞典成人居民群体中呼出气一氧化氮参考值及其影响因素分析
Reshed Abohalaka,Selin Ercan,Lauri Lehtimäki et al.
Reshed Abohalaka et al.
Background: Fractional exhaled nitric oxide (FENO) is used to differentiate asthma inflammatory phenotypes and guide its management. However, data on FENO reference values in a representative adult population is limited. ...