Anna Paioli,Michele Rocca,Luca Cevolani et al.
Anna Paioli et al.
Background: In patients with relapsed osteosarcoma, the surgical excision of all metastases, defined as second complete remission (CR-2), is the factor that mainly influences post-relapse survival (PRS). Currently a valid...
Central venous access related adverse events after trabectedin infusions in soft tissue sarcoma patients; experience and management in a nationwide multi-center study [0.03%]
意大利 trapsitinib 注射的全国多中心研究中的不良事件及处理经验
Michiel C Verboom,Jan Ouwerkerk,Neeltje Steeghs et al.
Michiel C Verboom et al.
Background: Trabectedin has shown efficacy against soft tissue sarcomas (STS) and has manageable toxicity. Trabectedin is administered through central venous access devices (VAD), such as subcutaneous ports with tunneled ...
Radiotherapy in the management of gist: state of the art and new potential scenarios [0.03%]
胃肠间质瘤诊疗现状及新的潜在模式radiotherapy in the management of gist: state of the art and new potential scenarios
L Gatto,M Nannini,M Saponara et al.
L Gatto et al.
Background: Gastrointestinal stromal tumor (GIST) is the most common mesenchymal neoplasm of the gastrointestinal tract. The main treatment for localized gastrointestinal stromal tumors is surgical resection. Unresectable...
Response to anti-PD1 therapy with nivolumab in metastatic sarcomas [0.03%]
抗PD1疗法nivolumab治疗转移性肉瘤的疗效分析
L Paoluzzi,A Cacavio,M Ghesani et al.
L Paoluzzi et al.
Background: Manipulation of immune checkpoints such as CTLA4 or PD-1 with targeted antibodies has recently emerged as an effective anticancer strategy in multiple malignancies. Sarcomas are a heterogeneous group of diseas...
Catherine McCarthy,Monika Hofer,Marianna Vlychou et al.
Catherine McCarthy et al.
Background: Extracranial metastasis of malignant meningioma to soft tissues is extremely rare and its clinical, radiological and pathological features are not well-characterised. ...
Clinical implications of repeated drug monitoring of imatinib in patients with metastatic gastrointestinal stromal tumour [0.03%]
伊马替尼重复药代动力学监测在胃肠道间质瘤晚期患者中的临床意义分析
Ivar Hompland,Øyvind Sverre Bruland,Kumari Ubhayasekhera et al.
Ivar Hompland et al.
Background: Imatinib mesylate (IM) is the preferred treatment for the majority of patients with metastatic gastrointestinal stromal tumour (GIST). Low trough IM concentration (Cmin) values have been associated with poor c...
Gulcan Bulut,Anil Ozluk,Atike Pınar Erdogan et al.
Gulcan Bulut et al.
Background: Aggressive fibromatosis (AF), also known as desmoid tumor, is an uncommon soft tissue neoplasm. AF does not metastasize, but it is locally invasive and its propensity for recurrence after conservative resectio...
Adam Dangoor,Beatrice Seddon,Craig Gerrand et al.
Adam Dangoor et al.
Soft tissue sarcomas (STS) are rare tumours arising in mesenchymal tissues, and can occur almost anywhere in the body. Their rarity, and the heterogeneity of subtype and location means that developing evidence-based guidelines is complicate...
Efficacy of pazopanib and sunitinib in advanced axial chordoma: a single reference centre case series [0.03%]
帕唑帕尼和索拉非尼治疗轴向基底节肿瘤的效果：单中心病例系列研究报告
Astrid Lipplaa,Sander Dijkstra,Hans Gelderblom
Astrid Lipplaa
Background: Chordomas are rare malignant tumours of the axial skeleton and skull base supposed to arise from cellular remnants of the notochord. These tumours have the potential to metastasize (30-40 %), usually in the la...
Outcome and the effect of age and socioeconomic status in 1318 patients with synovial sarcoma in the English National Cancer Registry: 1985-2009 [0.03%]
英国全国癌症登记处1318例滑膜肉瘤患者的结局及其与年龄和经济社会地位的关系：1985～2009年
Bernadette Brennan,Charles Stiller,Robert Grimer et al.
Bernadette Brennan et al.
Background: The role of age as a prognostic factor has been examined in single institutional studies and in larger data sets from the SEER database, showing a survival advantage for younger versus adult patients with syno...