Tenosynovial giant cell tumor: case report of a patient effectively treated with pexidartinib (PLX3397) and review of the literature [0.03%]
十肽达替尼治疗腱鞘巨细胞瘤的病例报道及文献复习
Nicholas Giustini,Nicholas M Bernthal,Susan V Bukata et al.
Nicholas Giustini et al.
Background: Tenosynovial giant cell tumors (TGCTs) or giant cell tumors of tendon sheath are neoplasms that arise in the synovium. They can be categorized as nodular (localized) or diffuse type (D-TGCT). Historically, sur...
Reversible rituximab-induced rectal Kaposi's sarcoma misdiagnosed as ulcerative colitis in a patient with HIV-negative follicular lymphoma [0.03%]
一名HIV阴性的滤泡性淋巴瘤患者的可逆的美罗华诱导的肛门卡波西肉瘤误诊为溃疡性结肠炎病例报告
Emilien Billon,Anne-Marie Stoppa,Lena Mescam et al.
Emilien Billon et al.
Background: Kaposi's sarcoma is a low-grade mesenchymal angioproliferative tumor, most commonly observed in immunocompromised individuals, such as HIV-infected patients. Iatrogenic Kaposi's sarcoma occurs in patients unde...
Regional chemotherapy by isolated limb perfusion prior to surgery compared with surgery and post-operative radiotherapy for primary, locally advanced extremity sarcoma: a comparison of matched cohorts [0.03%]
术前区域化疗与术后放疗治疗局部晚期四肢原始肉瘤的对比研究：配对队列分析
Jens Jakob,Henry G Smith,Michelle J Wilkinson et al.
Jens Jakob et al.
Background: Induction chemotherapy by isolated limb perfusion (ILP) with melphalan and tumour necrosis factor-α is an effective strategy to facilitate limb-conserving surgery in locally advanced extremity sarcoma. In a c...
Non-canonical WNT6/WNT10A signal factor expression in EBV+ post-transplant smooth muscle tumors [0.03%]
EB病毒感染的移植物平滑肌肿瘤非经典WNT6/WNT10A信号因子表达
Kristin Teiken,Mark Kuehnel,Jan Rehkaemper et al.
Kristin Teiken et al.
Post-transplant smooth muscle tumors (PTSMTs) are rare mesenchymal neoplasms which occur after solid organ or haematopoietic stem cell transplantation. PTSMT typically consist of Epstein-Barr-virus (EBV)+ smooth muscle-like cells and show a...
Aggressive fibromatosis response to tamoxifen: lack of correlation between MRI and symptomatic response [0.03%]
甲氨蝶呤治疗侵袭性纤维瘤病的疗效与磁共振成像及临床症状之间的关系研究
M Libertini,I Mitra,W T A van der Graaf et al.
M Libertini et al.
Background: One of the commonly used systemic agents for the treatment of aggressive fibromatosis is the anti-oestrogen drug tamoxifen. However, data on efficacy and optimum methods of response assessment are limited, con...
Treatment patterns and survival among older adults in the United States with advanced soft-tissue sarcomas [0.03%]
美国晚期软组织肉瘤老年人的治疗模式和生存率
Rohan C Parikh,Maria Lorenzo,Lisa M Hess et al.
Rohan C Parikh et al.
Background: To describe patient and tumor characteristics, treatments, and survival among older adults in the United States with advanced soft-tissue sarcoma (STS), across and by categories of specifically defined histolo...
Smoking is predictive of poorer distant metastasis-free and progression free-survival in soft tissue sarcoma patients treated with pre-operative radiotherapy or chemoradiotherapy [0.03%]
术前放疗和同期放化疗软组织肉瘤患者吸烟预测远处转移生存率和无病进展生存率较低
Nicholas P Gannon,David M King,Manpreet Bedi
Nicholas P Gannon
Background: Soft tissue sarcomas (STS) are often treated with pre-operative radiation (RT), with or without chemotherapy, followed by wide local excision. Prognosis for these patients involves an interplay of tumor and pa...
Unicentric epithelioid hemangioendothelioma of the calcaneus: a case report and review of literature [0.03%]
跟骨上皮样血管内皮细胞瘤1例报告及文献复习
Mark C Plumby,Patrick Bacaj,Brock A Lindsey
Mark C Plumby
Background: This review of the literature combined with a clinical case will allow the illustration of a favorable outcome of this variable low grade malignancy, display a role for limb salvage surgery with intralesional ...
Case Reports
Clinical sarcoma research. 2018 Apr 6:8:5. DOI:10.1186/s13569-018-0092-z 2018
Survival is influenced by approaches to local treatment of Ewing sarcoma within an international randomised controlled trial: analysis of EICESS-92 [0.03%]
局部治疗方案影响EWING肉瘤国际随机对照试验中患者的预后——EICESS-92研究分析
Jeremy Whelan,Allan Hackshaw,Anne McTiernan et al.
Jeremy Whelan et al.
Background: Two national clinical trial groups, United Kingdom Children's Cancer and Leukaemia Group (CCLG) and the German Paediatric Oncology and Haematology Group (GPOH) together undertook a randomised trial, EICESS-92,...
The use of whole exome sequencing and murine patient derived xenografts as a method of chemosensitivity testing in sarcoma [0.03%]
用于肉瘤化学敏感性检测的外显子组测序和小鼠患者来源异种移植模型的方法学应用研究
Nicholas Calvert,Jiansha Wu,Sophie Sneddon et al.
Nicholas Calvert et al.
Background: Soft tissue and bone sarcoma represent a broad spectrum of different pathology and genetic variance. Current chemotherapy regimens are derived from randomised trials and represent empirical treatment. Chemosen...