An experimental study on the effect of symptom expectations on mental fatigue and motivation in people with primary biliary cholangitis [0.03%]
一项关于症状预期对原发性胆汁性肝硬化患者心理疲劳和动机影响的实验研究
Laura Buck,Jule Herzberg,Bert Lenaert et al.
Laura Buck et al.
Fatigue is the most common symptom in people with primary biliary cholangitis (PBC) and resistant to current treatment modalities. The aim of this study was to investigate the effect of negative and positive fatigue expectations in people w...
Randomized Controlled Trial
Scientific reports. 2025 Aug 26;15(1):31464. DOI:10.1038/s41598-025-16191-2 2025
COL4A1 as a potential prognostic biomarker with functional roles in colon cancer progression [0.03%]
COL4A1作为结肠癌进展中的潜在预后生物标志物及功能基因
Qiusheng Li,Changjing Wang,Guiying Wang
Qiusheng Li
COL4A1, a key component of the basement membrane, has been increasingly implicated in tumor progression, yet its role in colon cancer remains incompletely understood. In this study, we conducted a comprehensive integrative analysis using tr...
The influence of citrus rootstocks on lime genotype tolerance to witches' broom disease [0.03%]
柑橘属砧木对霜霉病菌的影响
Samaneh Raheb,Sina Noorizadeh,Morteza Golmohammadi et al.
Samaneh Raheb et al.
Unfortunately, over the past two decades, Mexican lime orchards have faced a significant threat from witches' broom disease of lime (WBDL), associated with 'Candidatus Phytoplasma aurantifolia', leading to the ruin of many orchards in south...
Lipid membrane-camouflaged biomimetic nanoparticle for MicroRNA based therapeutic delivery to intestinal epithelial cells [0.03%]
一种用于基于microRNA的治疗性药物递送至肠上皮细胞的类脂膜伪装仿生纳米粒子
Manmeet Rawat,Sharda Nara,Yash Gupta et al.
Manmeet Rawat et al.
We have made artificial extracellular vesicles like nanoparticles that contain biologically active Agomir (miRNA mimic)/Antagomir (miRNA inhibitor) adsorbed on magnetic ZnO particles bound by a lipid bilayer membrane from Caco-2 cells (huma...
Low-energy shock waves improve the bacterial detection of Staphylococcus aureus biofilms on polyethylene [0.03%]
低能量冲击波可以改善聚乙烯上金黄色葡萄球菌生物被膜的检测率
Sabrina Böhle,Victoria Horbert,Sebastian Rohe et al.
Sabrina Böhle et al.
With the increasing number of total joint arthroplasties and the associated increase in periprosthetic infections, the further development of non-invasive examination methods to improve bacterial detection is becoming increasingly important...
Metformin lotion as a novel approach to prevent tendinopathy induced by mechanical overuse [0.03%]
用于预防机械过度使用引起的跟腱病的二甲双胍外用新方法
Jianying Zhang,Derek Maloney,Vasyl Pastukh et al.
Jianying Zhang et al.
Tendinopathy is a common overuse injury with limited preventive options. This study evaluated a novel topical metformin lotion (ML) for its ability to prevent Achilles tendinopathy induced by intensive treadmill running (ITR) in mice. ML at...
Combination of knockout serum replacement and plasma rich in growth factors does not support in vitro spermatogenesis in mice [0.03%]
敲除胎牛血清和富生长因子血浆不能支持小鼠体外精子发生
Seyyed Amir Moradian,Sajed Khaledi,Zahra Amirkhani et al.
Seyyed Amir Moradian et al.
Cancer treatments can lead to infertility, particularly in prepubertal boys who cannot preserve sperm before therapy. In vitro spermatogenesis offers a promising strategy for fertility preservation in this population by enabling the develop...
Decoding potential lncRNA and disease associations through graph representation learning and gradient boosting with histogram [0.03%]
基于图表示学习和梯度提升组学数据的长链非编码RNA疾病关联预测研究
Lili Tang,Longlong Liu,Yan Jiang et al.
Lili Tang et al.
Long noncoding RNAs (lncRNAs) are important regulators and promising targets for complex diseases. They have manifested dense relationships with various diseases. Although laboratory techniques have validated many lncRNA-disease association...
Methionine enkephalin upregulates the immune function of RAW264.7 cells to inhibit the infection of Nelson Bay orthoreoviruses [0.03%]
甲硫氨酸脑啡肽通过上调RAW264.7细胞免疫功能抑制NELSON BAY正黏病毒属传染作用
Xiaoli Tao,Xiaomeng Wang,Zhuping Ma et al.
Xiaoli Tao et al.
Preliminary research has found that MENK can upregulate the antiviral state of macrophages to inhibit influenza virus infection. To further study the immunomodulatory mechanism of MENK in macrophages against reovirus, we used RNA-Seq techno...