On the formalization of multi-scale and multi-science processes for integrative biology [0.03%]
整合生物学中多尺度、跨学科过程的规范化形式化研究
Vanessa Díaz-Zuccarini,César Pichardo-Almarza
Vanessa Díaz-Zuccarini
The aim of this work is to introduce the general concept of 'Bond Graph' (BG) techniques applied in the context of multi-physics and multi-scale processes. BG modelling has a natural place in these developments. BGs are inherently coherent ...
David P Nickerson,Jonna R Terkildsen,Kirk L Hamilton et al.
David P Nickerson et al.
We present the development of a tool, which provides users with the ability to visualize and interact with a comprehensive description of a multi-scale model of the renal nephron. A one-dimensional anatomical model of the nephron has been c...
Coupled personalization of cardiac electrophysiology models for prediction of ischaemic ventricular tachycardia [0.03%]
耦合的心脏电生理模型个性化以预测缺血性室速
Jatin Relan,Phani Chinchapatnam,Maxime Sermesant et al.
Jatin Relan et al.
In order to translate the important progress in cardiac electrophysiology modelling of the last decades into clinical applications, there is a requirement to make macroscopic models that can be used for the planning and performance of the c...
Left ventricular modelling: a quantitative functional assessment tool based on cardiac magnetic resonance imaging [0.03%]
基于心脏磁共振成像的左心室建模定量功能评估工具
C A Conti,E Votta,C Corsi et al.
C A Conti et al.
We present the development and testing of a semi-automated tool to support the diagnosis of left ventricle (LV) dysfunctions from cardiac magnetic resonance (CMR). CMR short-axis images of the LVs were obtained in 15 patients and processed ...
Visualization and simulated surgery of the left ventricle in the virtual pathological heart of the Virtual Physiological Human [0.03%]
虚拟生理人体中病态心脏左心室的可视化与模拟手术研究
N J B McFarlane,X Lin,Y Zhao et al.
N J B McFarlane et al.
Ischaemic heart failure remains a significant health and economic problem worldwide. This paper presents a user-friendly software system that will form a part of the virtual pathological heart of the Virtual Physiological Human (VPH2) proje...
Multi-scale simulations of the dynamics of in-stent restenosis: impact of stent deployment and design [0.03%]
血管内支架植入及设计对再狭窄的影响的多尺度模拟研究
Hannan Tahir,Alfons G Hoekstra,Eric Lorenz et al.
Hannan Tahir et al.
Neointimal hyperplasia, a process of smooth muscle cell re-growth, is the result of a natural wound healing response of the injured artery after stent deployment. Excessive neointimal hyperplasia following coronary artery stenting results i...
euHeart: personalized and integrated cardiac care using patient-specific cardiovascular modelling [0.03%]
euHeart:利用基于患者的个性化心血管模型进行综合心脏治疗
Nic Smith,Adelaide de Vecchi,Matthew McCormick et al.
Nic Smith et al.
The loss of cardiac pump function accounts for a significant increase in both mortality and morbidity in Western society, where there is currently a one in four lifetime risk, and costs associated with acute and long-term hospital treatment...
Influence of different computational approaches for stent deployment on cerebral aneurysm haemodynamics [0.03%]
不同的支架展开计算方法对脑动脉瘤血流动力学影响的研究
Annarita Bernardini,Ignacio Larrabide,Hernán G Morales et al.
Annarita Bernardini et al.
Cerebral aneurysms are abnormal focal dilatations of artery walls. The interest in virtual tools to help clinicians to value the effectiveness of different procedures for cerebral aneurysm treatment is constantly growing. This study is focu...
Computational modelling and evaluation of cardiovascular response under pulsatile impeller pump support [0.03%]
脉动叶轮泵支持下心血管反应的计算建模与评估
Yubing Shi,Alistair G Brown,Patricia V Lawford et al.
Yubing Shi et al.
This study presents a numerical simulation of cardiovascular response in the heart failure condition under the support of a Berlin Heart INCOR impeller pump-type ventricular assist device (VAD). The model is implemented using the CellML mod...
@neurIST complex information processing toolchain for the integrated management of cerebral aneurysms [0.03%]
用于复合信息处理的工具链在脑动脉瘤综合管理中的应用研究
M C Villa-Uriol,G Berti,D R Hose et al.
M C Villa-Uriol et al.
Cerebral aneurysms are a multi-factorial disease with severe consequences. A core part of the European project @neurIST was the physical characterization of aneurysms to find candidate risk factors associated with aneurysm rupture. The proj...