Response to treatment and adverse events associated with use of recombinant activated factor VII in children: a retrospective cohort study [0.03%]
重组活化因子VII在儿童中的治疗反应及不良事件：一项回顾性队列研究
James D Cooper,Arthur K Ritchey
James D Cooper
Background: Recombinant activated factor VII (rFVIIa) is United States (US) Food and Drug Administration (FDA)-approved for patients with hemophilia with inhibitors or congenital factor VII deficiency. Initial reports of ...
Polypharmacy and inappropriate medication use in patients with dementia: an underresearched problem [0.03%]
痴呆患者用药不当和用药品种过多问题：一个被忽视的问题
Carole Parsons
Carole Parsons
Multimorbidity and polypharmacy are increasingly prevalent across healthcare systems and settings as global demographic trends shift towards increased proportions of older people in populations. Numerous studies have demonstrated an associa...
Mario Cazzola,Luigino Calzetta,Paola Rogliani et al.
Mario Cazzola et al.
Tiotropium is now delivered via two different inhaler devices: the original Handihaler 18 μg once daily, which uses a powder formulation; and the newer Respimat Soft Mist Inhaler (SMI) 5 μg once daily. It has been questioned whether the t...
An exploratory factor analysis of the spontaneous reporting of severe cutaneous adverse reactions [0.03%]
严重皮肤不良反应自发报告的探索性因素分析
Manfred Hauben,Eric Hung,Wen-Yaw Hsieh
Manfred Hauben
Background: Severe cutaneous adverse reactions (SCARs) are prominent in pharmacovigilance (PhV). They have some commonalities such as nonimmediate nature and T-cell mediation and rare overlap syndromes have been documente...
QT interval prolongation and torsades de pointes with oxaliplatin [0.03%]
奥沙利铂引起Q-T间期延长和尖端扭转型室速的心脏毒性
Jules C Hancox,Rachel E Caves,Stéphanie C M Choisy et al.
Jules C Hancox et al.
Sangeeta Sharma,Fauzia Tabassum,Sarbjeet Khurana et al.
Sangeeta Sharma et al.
Background: To explore interprofessionals' perceptions about patient safety, particularly medication safety and associated factors and barriers. Methods: ...
Rifampicin and isoniazid plasma concentrations in relation to adverse reactions in tuberculosis patients: a retrospective analysis [0.03%]
Rifampicin和异烟肼的血浆浓度与结核病患者的不良反应的相关性：回顾性分析
L Aït Moussa,O El Bouazzi,S Serragui et al.
L Aït Moussa et al.
Objective: High concentrations of antituberculosis (anti-TB) drugs can be associated with many adverse drug reactions (ADRs). The objective of this study was to examine the plasma concentrations of rifampicin (RMP) and is...
Nidhi Jain,Malvi Savani,Manyoo Agarwal et al.
Nidhi Jain et al.
Citalopram and escitalopram: adverse cardiac outcomes in medically ill inpatients [0.03%]
西汀普兰和埃斯西汀普兰在有合并症的住院患者中产生不良心脏结局的风险较高
Dominique Elie,Saeid Noohi,André Do et al.
Dominique Elie et al.
Anticholinergic medication use and dementia: latest evidence and clinical implications [0.03%]
抗胆碱药物的使用与痴呆：最新证据及其临床意义
Shelly L Gray,Joseph T Hanlon
Shelly L Gray
Use of medications with anticholinergic activity is widespread in older adults. Several studies have highlighted that anticholinergic use may be associated with an increased risk of dementia. The objective of this narrative review is to des...