Apixaban, concomitant medicines and spontaneous reports of haemorrhagic events [0.03%]
阿哌沙班、伴随药物及自发报告的出血事件
Gillian E Caughey,Lisa M Kalisch Ellett,John D Barratt et al.
Gillian E Caughey et al.
Introduction: Little is known about the potential safety issues associated with apixaban in clinical practice and their reporting in spontaneous adverse event (SAE) databases. ...
The impact of database restriction on pharmacovigilance signal detection of selected cancer therapies [0.03%]
数据库限制对选定癌症疗法药物警戒信号检测的影响
Manfred Hauben,Eric Hung,Jennifer Wood et al.
Manfred Hauben et al.
Background: The aim of this study was to investigate whether database restriction can improve oncology drug pharmacovigilance signal detection performance. ...
Proton pump inhibitors and risk of readmission and mortality in older patients discharged from a tertiary hospital to residential aged care facilities [0.03%]
质子泵抑制剂与三级医院老年患者出院到养老院再入院和死亡风险的关系
Matthew A Pegoli,Maneesha Dedigama,Arduino A Mangoni et al.
Matthew A Pegoli et al.
Posterior reversible encephalopathy syndrome with colitis in a patient treated with panitumumab [0.03%]
帕尼单抗治疗患者出现可逆性后部脑病综合征伴随结肠炎
Céline Blaye,Xavier Buy,Marine Gross-Goupil et al.
Céline Blaye et al.
A practical approach to the pharmacological management of hypertension in older people [0.03%]
老年人高血压的药物治疗实用方法
Nikesh Parekh,Amy Page,Khalid Ali et al.
Nikesh Parekh et al.
Hypertension is the leading cause of cardiovascular (CV) morbidity and mortality in adults over the age of 65. The first part of this paper is an overview, summarizing the current guidelines on the pharmacological management of hypertension...
Adverse drug reactions in therapeutic hypothermia after cardiac arrest [0.03%]
心肺复苏后目标体温管理的不良反应事件分析：2019年国际指南更新要点
Robert Witcher,Amy L Dzierba,Catherine Kim et al.
Robert Witcher et al.
Background: Therapeutic hypothermia (TH) improves survival and neurologic function in comatose survivors of cardiac arrest. Many medications used to support TH have altered pharmacokinetics and pharmacodynamics during thi...
Attention-deficit hyperactivity disorder medication use: factors involved in prescribing, safety aspects and outcomes [0.03%]
注意缺陷多动障碍药物使用：开药因素、安全性及预后方面的问题
Jose Martinez-Raga,Amparo Ferreros,Carlos Knecht et al.
Jose Martinez-Raga et al.
While treatment of patients with attention-deficit hyperactivity disorder (ADHD) is based on a multimodal approach that combines medication with specific psychological interventions, pharmacotherapy alone is generally considered an essentia...
The SENATOR project: developing and trialling a novel software engine to optimize medications and nonpharmacological therapy in older people with multimorbidity and polypharmacy [0.03%]
SENATOR项目：开发和试行一种新型软件引擎以优化多病共存和多种药物治疗的老年人的药物和非药物治疗方案
Roy L Soiza,Selvarani Subbarayan,Cherubini Antonio et al.
Roy L Soiza et al.
Efficacy and safety of the target-specific oral anticoagulants for stroke prevention in atrial fibrillation: the real-life evidence [0.03%]
新型口服抗凝药物预防房颤患者卒中的疗效和安全性：真实世界证据分析
Vincenzo Russo,Anna Rago,Riccardo Proietti et al.
Vincenzo Russo et al.
The aim of our article is to provide a concise review for clinicians entailing the main studies that evaluated the efficacy and safety of target-specific oral anticoagulants (TSOAs) for thromboembolic stroke prevention in the real-world set...
Adverse drug reactions due to cancer chemotherapy in a tertiary care teaching hospital [0.03%]
三级甲等教学医院癌症化疗的药物不良反应
Julie Birdie Wahlang,Purnima Devi Laishram,Dhriti Kumar Brahma et al.
Julie Birdie Wahlang et al.
Background: An adverse drug reaction (ADR) is defined by World Health Organization (WHO) as 'Any response to a drug which is noxious, unintended and occurs at doses used in man for prophylaxis, diagnosis or therapy'. ADRs...