Jonathan J H Bray,Jules C Hancox
Jonathan J H Bray
A mathematical framework to quantify the masking effect associated with the confidence intervals of measures of disproportionality [0.03%]
量化 disproportionality 指标置信区间掩蔽效应的数学框架
François Maignen,Manfred Hauben,Jean-Michel Dogné
François Maignen
Background: The lower bound of the 95% confidence interval of measures of disproportionality (Lower95CI) is widely used in signal detection. Masking is a statistical issue by which true signals of disproportionate reporti...
Screening for valve disease in patients with hyperprolactinaemia disorders prescribed cabergoline: a service evaluation and literature review [0.03%]
卡麦角林治疗高催乳激素血症患者的瓣膜病筛查：一项服务评估与文献回顾
David Gamble,Rachel Fairley,Roderick Harvey et al.
David Gamble et al.
Objectives: The indication for screening for valvular heart disease in patients taking cabergoline is based on evidence from patients with Parkinson's disease on high-dose medication. However, current patients take much l...
Rafael Daroca-Pérez,Miguel F Carrascosa
Rafael Daroca-Pérez
Multidrug intolerance in the treatment of hypertension: result from an audit of a specialized hypertension service [0.03%]
高血压治疗中的多种药物不良反应：专科高血压诊所的审核结果
Basil N Okeahialam
Basil N Okeahialam
Background: Hypertension as a cardiovascular disease risk factor continues to take a heavy toll on the population despite efforts with containment. Poor control, even among those on treatment, is part of the challenge and...
Risk factors for adverse drug reactions in pediatric inpatients: a systematic review [0.03%]
儿童住院患者不良药物反应的风险因素：系统评价
Paulo Henrique Santos Andrade,Adriano da Silva Santos,Carlos Adriano Santos Souza et al.
Paulo Henrique Santos Andrade et al.
Background: The main objective of the present systematic review is to identify potential risk factors for adverse drug reactions (ADRs) through prospective cohort studies in pediatric inpatients. ...
Derek Stewart,Tesnime Jebara,Scott Cunningham et al.
Derek Stewart et al.
Many countries have implemented nonmedical prescribing (NMP) and many others are scoping prescribing practices with a view to developing NMP. This paper provides a future perspective on NMP in light of findings of an umbrella review of aspe...
Cardiovascular and cerebrovascular risk with nonsteroidal anti-inflammatory drugs and cyclooxygenase 2 inhibitors: latest evidence and clinical implications [0.03%]
非甾体抗炎药和环氧化酶-2抑制剂的心血管及脑血管风险：最新的证据及其临床意义
Andrea Fanelli,Daniela Ghisi,Pierangelo Lora Aprile et al.
Andrea Fanelli et al.
Observational studies and meta-analyses have shown that the administration of nonsteroidal anti-inflammatory drugs (NSAIDs), especially when prescribed at high doses for long periods of time, can potentially increase the risk of cardiovascu...
Baclofen overdose mimicking anoxic encephalopathy: a case report and review of the literature [0.03%]
巴氯芬中毒引起的假性缺氧脑病的病例报告和文献回顾
John J Miller
John J Miller
A patient who has overdosed on baclofen can present with significant neurological symptoms suggestive of a serious brain insult, but with appropriate diagnosis and treatment they often fully recover within 72 h. If the patient had been main...