Incident adverse drug reactions in geriatric inpatients: a multicentred observational study [0.03%]
一项多中心观察研究：住院老年患者的药物不良事件反应
Amanda Lavan,Joseph Eustace,Darren Dahly et al.
Amanda Lavan et al.
Background: Adverse drug reactions (ADRs) are common in older adults and frequently have serious clinical and economic consequences. This study was conducted as a feasibility study for a randomized control trial (RCT) tha...
Andrew Bate,Robert F Reynolds,Patrick Caubel
Andrew Bate
Arunkumar D Rana,Kinjal Dodiya,Manish J Barvaliya et al.
Arunkumar D Rana et al.
Pegloticase in gout treatment - safety issues, latest evidence and clinical considerations [0.03%]
peglitacase在痛风治疗中的安全性问题、最新证据及临床考虑因素
Allison Guttmann,Svetlana Krasnokutsky,Michael H Pillinger et al.
Allison Guttmann et al.
Gout is a common rheumatic condition, with increasing prevalence in recent decades. The mainstay of treatment for gout is oral urate-lowering therapy (ULT), typically with xanthine oxidase inhibitors (XOIs). Unfortunately, a proportion of p...
Using deep learning to improve medication safety: the untapped potential of social media [0.03%]
利用深度学习改善药物安全：社交媒体的潜力未被发掘
Jiaheng Xie,Daniel Dajun Zeng,Zachary A Marcum
Jiaheng Xie
Assessing and predicting drug-induced anticholinergic risks: an integrated computational approach [0.03%]
评估和预测药物引起的抗胆碱能风险：一种集成计算方法
Dong Xu,Heather D Anderson,Aoxiang Tao et al.
Dong Xu et al.
Background: Anticholinergic (AC) adverse drug events (ADEs) are caused by inhibition of muscarinic receptors as a result of designated or off-target drug-receptor interactions. In practice, AC toxicity is assessed primari...
Non-medical prescribing in New Zealand: an overview of prescribing rights, service delivery models and training [0.03%]
新西兰的非医学处方权：处方权、服务传递模式和培训概况概述
Rakhee Raghunandan,June Tordoff,Alesha Smith
Rakhee Raghunandan
Aim: In this paper, we aim to provide an updated source of information for nonmedical prescribing (NMP) in New Zealand (NZ). Methods: A...
Gastrointestinal adverse effects of cyclin-dependent kinase 4 and 6 inhibitors in breast cancer patients: a systematic review and meta-analysis [0.03%]
cyclin依赖性激酶4和6抑制剂治疗乳腺癌患者的胃肠不良反应：系统评价和 Meta分析
Kyrillus S Shohdy,Shaimaa Lasheen,Loay Kassem et al.
Kyrillus S Shohdy et al.
Background: Cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors show promising results in metastatic breast cancer. However, an increased incidence of adverse events is remarkable. Among others, gastrointestinal (GI) invo...
Adverse effects of proton-pump inhibitor use in older adults: a review of the evidence [0.03%]
质子泵抑制剂在老年人中使用的不良反应：证据回顾
Marina L Maes,Danielle R Fixen,Sunny Anne Linnebur
Marina L Maes
Proton-pump inhibitors (PPIs) are a widely prescribed class of medications used to treat acid-related disorders and use has significantly increased over the last few decades. PPIs are often inappropriately prescribed and since they have bee...