Treating hearts and minds: adverse cardiovascular effects of psychiatric medications [0.03%]
心血管系统精神药物的不良影响
Asdaq Shabbir Raja,Stephen J Leslie,Elizabeth Buist et al.
Asdaq Shabbir Raja et al.
Cardiovascular disease (CVD) is one of the leading causes of death in patients with severe mental illness (SMI), being ~3.3 times higher than in the general population. The adverse cardiovascular effects of psychiatric medications have shor...
Antimicrobial stewardship and the antibiotic market: why "Reserve" drugs require new economic models [0.03%]
抗菌药物管理与抗生素市场：为什么“储备”类药物需要新的经济学模式
Eleonora Castellana,Alessia Tarozzo,Rita Viglianti et al.
Eleonora Castellana et al.
The FMB scale: a multifactorial metric to assess the driving hazard of medicines beyond the DRUID system [0.03%]
超越DRUID系统的药物驾驶风险多因素评估指标FMB分级的开发与应用
Salvador Borja Ripoll,Vicente Traver,Lola Franco et al.
Salvador Borja Ripoll et al.
Background: Driving while undergoing pharmacological treatment poses a significant risk to road safety. The Driving under the Influence of Drugs, Alcohol, and Medicines (DRUID) system, currently used to classify medicines...
Machine learning studies of drug-induced nephrotoxicity: a scoping review [0.03%]
基于机器学习的药物肾毒性的研究：综述型研究
Mawardi Ihsan,Shu-Ting Chang,Wei-Kai Chan et al.
Mawardi Ihsan et al.
Background: Machine learning methods have emerged as a promising approach to prevent drug-induced nephrotoxicity. Objective: This revie...
Efficacy and safety of ciprofol versus propofol for sedation in hysteroscopy: a systematic review and meta-analysis [0.03%]
塞拉西泮与右美托咪啶用于宫腔镜镇静的疗效和安全性：系统评价和-meta分析
Zoha Anwar,Hafsa Ahsun,Taha Iqbal et al.
Zoha Anwar et al.
Background: Hysteroscopy, a popular outpatient gynecological procedure, often requires sedation due to pain caused by endometrial manipulation and cervical dilation. Propofol, the current standard sedative, has adverse ef...
Metformin-associated lactic acidosis in an elderly diabetic patient without classical risk factors: a case report [0.03%]
一例无典型危险因素的二甲双胍相关乳酸性酸中毒患者的病例报告
Yali Zheng,Jia Sun,Peng Zhang et al.
Yali Zheng et al.
Metformin is a cornerstone medication and first-line therapy for type 2 diabetes mellitus (T2DM), with a well-established safety profile and widespread use over many years. Its most common adverse effects are gastrointestinal in nature. How...
The magnitude of drug-related problems, typology, and predictors among patients admitted to the pediatric intensive care unit: impact of pharmacist-led interventions in Northwest Ethiopia [0.03%]
药师主导干预在埃塞俄比亚西北部儿科重症监护病房患者中的药物相关问题的影响：药物相关问题的规模、类型和预测因素
Abel Temeche Kassaw,Getachew Yitayew Tarekegn,Tigabu Eskeziya Zerihun et al.
Abel Temeche Kassaw et al.
Background: Drug-related problems (DRPs) are a significant concern in hospitalized patients. In Ethiopia, DRPs occur at a rate of 9.2 per 100 admissions and 9.4 per 1,000 patient days; however, pediatric-specific data are...
Disparities and trends in drug-related adverse reaction mortality in the United States, 1999-2020 [0.03%]
1999至2020年美国药物不良反应死亡率的差异及趋势
Liwei Guo,Xiuxun Dong
Liwei Guo
Background: Adverse drug reactions (ADRs) are a leading cause of morbidity and mortality worldwide. Despite advances in pharmacovigilance, population-level evidence on long-term trends and disparities in ADR-related morta...
Donor and recipient genetic polymorphisms modulate tacrolimus pharmacokinetics during voriconazole co-therapy: a drug-drug interaction study in liver transplant recipients [0.03%]
供体和受体的基因多态性调节伏立康唑联合他克莫司治疗时的他克莫司药代动力学：肝移植受者的药物相互作用研究
Jieling Li,Liubing Li,Yanzhe Xia et al.
Jieling Li et al.
Background: While recipient cytochrome P450 (CYP) genetic polymorphisms are established modulators of tacrolimus (TAC) pharmacokinetics, the combined effects of donor-derived hepatic and recipient intestinal CYP3A4/5 and ...
Andrew Bate,Philip Michael Tregunno
Andrew Bate