Developing and testing of an assessment tool for appropriate psychotropic drug prescribing in people with intellectual disabilities [0.03%]
智力障碍人群适宜心境稳定剂处方评估工具的制定和检验
Josien Jonker,Gerda Margaretha de Kuijper,Sytse Ulbe Zuidema
Josien Jonker
Background: Prescribing psychotropic drugs often leads to long-term use in people with intellectual disabilities. In this population, polypharmacy is also common, likely because of the high frequencies of comorbid somatic...
Building functional and sustainable pharmacovigilance systems: an analysis of pharmacovigilance development across high-, middle- and low-income countries [0.03%]
构建有效的可持续的药品监管系统：分析高低收入国家的药品监管发展状况
Olga Menang,Peter van Eeuwijk,Karen Maigetter et al.
Olga Menang et al.
Background: There has been notable progress in pharmacovigilance (PV) in low- and middle-income countries (LMIC) in the last decade. However, only a few of these PV systems are fully functional, unlike in high-income coun...
Abuse liability for esketamine in a cohort of patients undergoing an acute treatment course to manage treatment-resistant depression: a secondary analysis of an observational study in real-world clinical practicee [0.03%]
艾斯氯胺酮治疗难治性抑郁患者的药物滥用倾向及耐受性的队列研究：一项真实世界观察性研究的二次分析
Gilmar Gutierrez,Gustavo Vazquez,Nisha Ravindran et al.
Gilmar Gutierrez et al.
Background: Intranasal (IN) esketamine has become an effective and well-tolerated therapeutic option for the management of treatment-resistant depression within major depressive disorder (MDD-TRD). Despite these promising...
Jingkai Di,Yujia Xi,Likun Qi et al.
Jingkai Di et al.
Background: There are still some points of controversy regarding the adverse events associated with celecoxib use, particularly in terms of thrombosis. Ob...
Factors related to dosing frequency and route of administration in methotrexate intolerance among patients with rheumatoid arthritis: a cross-sectional study [0.03%]
一项关于类风湿关节炎患者甲氨蝶呤不耐受与给药频率及给药途径相关性的横断面研究的因素
Haya M Almalag,Jawza F Alsabhan,Abdurhman S Alarfaj et al.
Haya M Almalag et al.
Background: Methotrexate is central to the management of rheumatoid arthritis (RA). However, its use is often limited by methotrexate intolerance. Objecti...
Pharmacovigilance processes in low- and middle-income countries: moving from data collection to data analysis and interpretation [0.03%]
发展中国家的药品不良反应检测过程：从数据收集到数据分析和结果解释
Olga Menang,Peter van Eeuwijk,Karen Maigetter et al.
Olga Menang et al.
Background: The analysis and interpretation of pharmacovigilance data is an essential component of the continuous benefit-risk assessment of authorised medicinal products. Effective pharmacovigilance data analysis starts ...
Adherence to WHO/INRUD prescription indicators in public hospitals: evidence from the Ashanti Region, Ghana [0.03%]
吉hana阿散蒂地区的公立医院遵守世卫组织/国际药物使用研究联盟处方指标的情况调查
Richard Delali Agbeko Djochie,Rita Owusu-Donkor,Elizabeth Modupe d&#x;Almeida et al.
Richard Delali Agbeko Djochie et al.
Background: Rational prescribing optimizes medicine use, reduces costs, and improves patient outcomes. However, adherence to rational prescribing practices varies, particularly in low- and middle-income countries like Gha...
Pharmacovigilance analysis of secondary primary malignancies and antibiotic interactions in CAR-T cell therapies [0.03%]
CAR-T细胞治疗中继发性原发恶性肿瘤及抗生素相互作用的药物警戒分析
Yun Peng,Yuxuan Song,Jiaxing Lin et al.
Yun Peng et al.
Background: Chimeric antigen receptor T-cell (CAR-T) cell therapy represents a significant advancement in cancer treatment, offering remarkable responses in certain hematologic malignancies. However, the risk of secondary...
Real-world insights into safety, tolerability, and predictive factors of adverse drug reactions in treating idiopathic pulmonary fibrosis with pirfenidone and nintedanib [0.03%]
吡非尼酮和尼达尼布治疗特发性肺纤维化真实世界安全性、耐受性和不良反应预测因素的见解
Alessio Provenzani,Daniele Leonardi Vinci,Miriam Alaimo et al.
Alessio Provenzani et al.
Background: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, life-threatening lung disease with a global incidence of 0.09-1.30 per 10,000 individuals. Pirfenidone and nintedanib are the approved treatments ...
Pharmacist support in the entry of blood drug concentration test order avoids vancomycin-induced kidney injury [0.03%]
药师支持的血液药物浓度检测申请录入可避免万古霉素致肾损伤
Naoki Yoshikawa,Chiaki Miyata,Hidehiko Koreeda et al.
Naoki Yoshikawa et al.
Background: Task shifting and sharing have been proposed as strategies to address healthcare staffing shortages and improve patient outcomes. In emergency and intensive care medicine, pharmacist interventions have shown p...