The use of a clinical decision support tool to assess the risk of QT drug-drug interactions in community pharmacies [0.03%]
社区药房使用临床决策支持工具评估QT药物相互作用风险的应用分析
Florine A Berger,Heleen van der Sijs,Teun van Gelder et al.
Florine A Berger et al.
Introduction: The handling of drug-drug interactions regarding QTc-prolongation (QT-DDIs) is not well defined. A clinical decision support (CDS) tool will support risk management of QT-DDIs. Therefore, we studied the effe...
Routine use of immunosuppressants is associated with mortality in hospitalised patients with COVID-19 [0.03%]
免疫抑制剂的常规使用与COVID-19住院患者的死亡率相关
Phyo K Myint,Ben Carter,Fenella Barlow-Pay et al.
Phyo K Myint et al.
Background: Whilst there is literature on the impact of SARS viruses in the severely immunosuppressed, less is known about the link between routine immunosuppressant use and outcome in COVID-19. Consequently, guidelines o...
Validation of a novel causality assessment scale for adverse events in non-small cell lung carcinoma patients treated with platinum and pemetrexed doublet chemotherapy [0.03%]
一项用于评估铂类联合培美曲塞双药化疗非小细胞肺癌不良事件因果关系量表的验证研究
Jyoti Bhagatram Sharma,Manjunath Nookala Krishnamurthy,Ankita Awase et al.
Jyoti Bhagatram Sharma et al.
Aim: Accurate causality assessment (CA) of adverse events (AEs) is important in clinical research and routine clinical practice. The Naranjo scale (NS) used for CA lacks specificity, leading to a high rate of false positi...
Systematic review of immunosuppressant guidelines in the COVID-19 pandemic [0.03%]
新冠肺炎大流行下的免疫抑制剂指南系统性回顾
Fenella Barlow-Pay,Thura Win Htut,Mina Khezrian et al.
Fenella Barlow-Pay et al.
Aims: Individuals taking immunosuppressants are at increased susceptibility to viral infections in general. However, due to the novel nature of the COVID-19, there is a lack of evidence about the specific risks of the dis...
Pharmacovigilance and the digital world in Italy: presentation of the results of a national survey [0.03%]
意大利的药物警戒与数字世界：全国调查结果介绍
Lisa Stagi,Ilenia Bocchi,Salvatore Bianco et al.
Lisa Stagi et al.
Background: The digital world has undergone an essential metamorphosis in recent years, making the easy sharing of information possible, including those related to pharmacovigilance and the safety aspects of pharmaceutica...
Adverse events associated with sodium glucose co-transporter 2 inhibitors: an overview of quantitative systematic reviews [0.03%]
钠葡萄糖共转运蛋白2抑制剂相关的不良事件：定量系统评价的概要分析
Ryan Pelletier,Kelvin Ng,Wajd Alkabbani et al.
Ryan Pelletier et al.
Background: Multiple published quantitative systematic reviews have reported on adverse events associated with the use of sodium glucose co-transporter 2 (SGLT-2) inhibitors in patients with type 2 diabetes mellitus. ...
The effect of different intensivist staffing patterns on the rate of potential drug-drug interactions in adult trauma intensive care units [0.03%]
不同专科医师配置模式对成人创伤重症监护病房潜在药物相互作用率的影响
Mansoor Masjedi,Mahtabalsadat Mirjalili,Ehsan Mirzaei et al.
Mansoor Masjedi et al.
Background: Drug-drug interactions (DDIs) have created alarming challenges for public health, especially in those admitted to intensive care units (ICUs). Many studies have shown that involvement of intensivists in the IC...
Michael Wohlfeiler,Karam Mounzer,Laurence Brunet et al.
Michael Wohlfeiler et al.
Introduction: A comprehensive assessment of liver disorders was conducted among people living with HIV (PLWH) on a new antiretroviral regimen based on common core agents. ...
Structured benefit-risk evaluation for medicinal products: review of quantitative benefit-risk assessment findings in the literature [0.03%]
药物的结构化利弊评估：对文献中定量利弊评估结果的回顾
Marie-Laure Kürzinger,Ludivine Douarin,Ievgeniia Uzun et al.
Marie-Laure Kürzinger et al.
A favorable benefit-risk profile remains an essential requirement for marketing authorization of medicinal drugs and devices. Furthermore, prior subjective, implicit and inconsistent ad hoc benefit-risk assessment methods have rightly evolv...
Identifying medication harm in hospitalised patients: a bimodal, targeted approach [0.03%]
住院患者药物损害的双向定位方法
Nazanin Falconer,Anne Spinewine,Matthew P Doogue et al.
Nazanin Falconer et al.