Fansidar drug induces cytotoxicity in some vital tissues in a rat model: combination defensive effect of selenium and zinc capsules [0.03%]
氨基蝶啶类药物诱导大鼠某些重要组织细胞毒性作用的实验研究硒与锌联合预防作用的研究报告
J K Akintunde,J A Ajiboye,E O Siemuri et al.
J K Akintunde et al.
Aim: Fansidar (FAN) is widely used as an antimalarial drug, but it may cause hepatoxicity, nephrotoxicity, and neurotoxicity. Hence, the study examines the cytoprotection of selenium (Se) and zinc (Zn) tablets against FAN...
The safety of ceftolozane-tazobactam for the treatment of acute bacterial infections: a systemic review and meta-analysis [0.03%]
セフトロゾアん-タゾバクタムによる急性细菌感染症治疗の安全性:系统的评価とmeta sakeika分析
Li-Ting Wang,Wei-Ting Lin,Chih-Cheng Lai et al.
Li-Ting Wang et al.
Objectives: The aim of this study was to conduct a meta-analysis to assess the clinical safety of ceftolozane-tazobactam for the treatment of acute bacterial infections in adult patients. ...
Paige L Morizio,Sara R Britnell,Andreina A Ottman
Paige L Morizio
Background and aims: Chemical impurities discovered in angiotensin receptor blocker (ARB) products in late 2018-2019 resulted in recalls of various products and has likely had downstream effects for patients and prescribe...
Tramadol-induced hiccups: a case-noncase study in the European pharmacovigilance database [0.03%]
欧洲药品不良反应数据库中诱导打嗝的曲马多病例-非病例研究
Montserrat García,Unax Lertxundi,Carmelo Aguirre
Montserrat García
Background: Hiccups are usually benign and self-limiting, but can sometimes be persistent. If left untreated, they can provoke severe discomfort, and even death. Hiccups can be idiopathic, organic, psychogenic, and caused...
Attitudes of ambulatory care older Nepalese patients towards deprescribing and predictors of their willingness to deprescribe [0.03%]
尼泊尔门诊老年患者减药态度及其愿意减药的影响因素调查研究
Shakti Shrestha,Roshan Giri,Hari Prasad Sapkota et al.
Shakti Shrestha et al.
Introduction: Older adults continue to receive potentially inappropriate medications necessitating the need for medication optimization, by deprescribing. To ensure a holistic approach to deprescribing, it is essential to...
Vaccine Safety Datalink infrastructure enhancements for evaluating the safety of maternal vaccination [0.03%]
疫苗安全数据链基础设施的改进，以评估产妇接种疫苗的安全性
Allison L Naleway,Bradley Crane,Stephanie A Irving et al.
Allison L Naleway et al.
Background: Identifying pregnancy episodes and accurately estimating their beginning and end dates are imperative for observational maternal vaccine safety studies using electronic health record (EHR) data. ...
Muscle relaxant use and the associated risk of incident frailty in patients with diabetic kidney disease: a longitudinal cohort study [0.03%]
糖尿病肾病患者肌肉松弛药使用及新发衰弱的关联性：纵向队列研究
Szu-Ying Lee,Jui Wang,Hung-Bin Tsai et al.
Szu-Ying Lee et al.
Background: Patients with diabetic kidney disease (DKD) are at an increased risk of frailty. The exposure to muscle relaxants frequently leads to adverse effects despite their modest therapeutic efficacy, but whether musc...
Anticholinergic burden measures and older people's falls risk: a systematic prognostic review [0.03%]
抗胆碱作用负担评分与老年人跌倒风险的系统性预后研究
Carrie Stewart,Martin Taylor-Rowan,Roy L Soiza et al.
Carrie Stewart et al.
Introduction: Several adverse outcomes have been associated with anticholinergic burden (ACB), and these risks increase with age. Several approaches to measuring this burden are available but, to date, no comparison of th...
Characteristics of voluntary reporting of adverse drug events related to antipsychotics in Australia: 14-year analysis [0.03%]
澳大利亚抗精神病药物不良事件自发报告的特征：14年分析
Hanan Khalil,Dimi Hoppe,Nabil Ameen
Hanan Khalil
Background: Retrospective analyses of large databases of treated patients can provide useful links to the presence of drug misuse or rare and infrequent adverse effects, such as agranulocytosis, diabetic ketoacidosis or n...
Jay Desai,Logan Key,Alyson Swindall et al.
Jay Desai et al.
Background: The most common cause of persistent hypoglycemia in infancy is hyperinsulinemic hypoglycemia. When conservative measures fail, providers often use medications to treat persistent hypoglycemia. Diazoxide is fir...