Safety surveillance and challenges in accelerated COVID-19 vaccine development [0.03%]
新冠病毒疫苗快速研发中的安全性监测与挑战
Abimbola Cole,Peggy Webster,Denny Van Liew et al.
Abimbola Cole et al.
The COVID-19 pandemic, caused by a novel type of coronavirus, continues to infect people, increasing morbidity and mortality across the globe. Measures to slow the transmission of the virus have had limited impact, and people, businesses, a...
Global safety monitoring of COVID-19 vaccines: how pharmacovigilance rose to the challenge [0.03%]
新冠肺炎疫苗的全球安全监测：药品不良反应检测系统应对挑战的方式
Annette Rudolph,Joseph Mitchell,Jim Barrett et al.
Annette Rudolph et al.
Pharmacovigilance (PV) came suddenly into the spotlight when several new vaccines, developed as a response to the COVID-19 pandemic, received emergency authorisation and were rolled out on a large scale in late 2020. The vaccines underwent ...
Motivating deprescribing conversations for patients with Alzheimer's disease and related dementias: a descriptive study [0.03%]
一项描述性研究：激励阿尔茨海默病和相关痴呆症患者进行减药对话
Mary T Antonelli,John S Cox,Cassandra Saphirak et al.
Mary T Antonelli et al.
Introduction: Older adults with Alzheimer's disease and related dementias (ADRD) are at increased risk of harm due to prescribing of potentially inappropriate medications. Encouraging patients and caregivers to talk with ...
Prevalence and global trends of polypharmacy among people living with HIV: a systematic review and meta-analysis [0.03%]
HIV感染者共病流行率和全球趋势：系统回顾和meta分析
Mohammed I Danjuma,Oyelola A Adegboye,Ahmed Aboughalia et al.
Mohammed I Danjuma et al.
Background: There has been a rising prevalence of polypharmacy among people living with HIV (PLWH). Uncertainty however remains regarding the exact estimates of polypharmacy among these cohorts of patients. ...
Patients' attitudes toward deprescribing and their experiences communicating with clinicians and pharmacists [0.03%]
患者对减药的态度及其与医务人员和药师沟通的经验
Kaylee M Lukacena,James W Keck,Patricia R Freeman et al.
Kaylee M Lukacena et al.
Purpose: Developing effective deprescribing interventions relies on understanding attitudes, beliefs, and communication challenges of those involved in the deprescribing decision-making process, including the patient, the...
Awareness, knowledge, and attitude toward adverse drug reaction (ADR) reporting among healthcare professionals in Ghana [0.03%]
关于加纳医疗保健专业人员的药品不良反应(ADR)报告意识、知识和态度的研究
Abena Ahwianfoa Yawson,Gordon Abekah-Nkrumah,Grace Adjei Okai et al.
Abena Ahwianfoa Yawson et al.
Background: Spontaneous reporting systems are the commonest means of reporting adverse drug reactions (ADRs) worldwide. Under-reporting remains a challenge particularly in developing countries among healthcare professiona...
Risk communication on vaccines during the COVID19 pandemic: is there room for small size or private initiatives? An Israeli experience [0.03%]
新冠肺炎大流行下的新冠疫苗风险沟通：小型机构或私人机构是否有可为之处？以色列的经验
Irene R Fermont,Ayalah Livneh,Michel Benhamou
Irene R Fermont
The scientific communication landscape has undergone a significant disruption since the COVID-19 pandemic: a huge number of publications, ample use of preprint publications, a fast-spreading digitalized information. This reflected the unpre...
Patients' views on Self-administration of Medication during hospitalisation: a mixed-methods study [0.03%]
住院患者对自主用药的看法：一项混合方法研究
Loes Johanna Maria van Herpen-Meeuwissen,Charlotte Linde Bekker,Nicky Cornelissen et al.
Loes Johanna Maria van Herpen-Meeuwissen et al.
Background: Inpatient Self-administration of Medication (SAM) increases patient involvement in medication management and may increase medication safety. Its implementation is impeded. Successful and sustainable implementa...
Could chlorophyllins improve the safety profile of beta-d-N4-hydroxycytidine versus N-hydroxycytidine, the active ingredient of the SARS-CoV-2 antiviral molnupiravir? [0.03%]
叶绿素能否改善β-D-N4-羟基胞苷的安全性，而N-羟基胞苷是SARS-CoV-2抗病毒药物莫那匹拉韦的有效成分？
Nicole F Clark,Andrew W Taylor-Robinson,Kirsten Heimann
Nicole F Clark
Could natural plant pigment (chlorophyll) derivatives (chlorophyllins) improve the safety of the antiviral Molnupiravir, used to treat COVID-19 disease? Molnupiravir, a specific SARS-CoV-2 antiviral, may cause adverse genetic changes and th...
The patterns and implications of potentially suboptimal medicine regimens among older adults: a narrative review [0.03%]
老年人潜在欠佳用药模式及影响的综述
Georgie B Lee,Christopher Etherton-Beer,Sarah M Hosking et al.
Georgie B Lee et al.
In the context of an ageing population, the burden of disease and medicine use is also expected to increase. As such, medicine safety and preventing avoidable medicine-related harm are major public health concerns, requiring further researc...