Drug-drug interaction between tacrolimus and caspofungin in Chinese kidney transplant patients with different CYP3A5 genotypes [0.03%]
他克莫司与卡泊芬净在不同CYP3A5基因型中国肾移植患者中的药物相互作用
Yundi Zhang,Bowen Shen,Yue Li et al.
Yundi Zhang et al.
Background: The effect of drug-drug interaction between tacrolimus and caspofungin on the pharmacokinetics of tacrolimus in different CYP3A5 genotypes has not been reported in previous studies. ...
Harmonization of individual case safety reports transmission requirements among PAHO reference authorities: a review of their current regulation [0.03%]
PAHO参考当局INDIVIDUAL CASE SAFETY REPORTS传输要求的统一：对其现行法规的回顾
Antonio Lomeli-Silva,Homero Contreras-Salinas,Mayra Yolanda Barajas-Virgen et al.
Antonio Lomeli-Silva et al.
To perform optimal monitoring of the safety profile in the postmarketing phase, Marketing Authorization Holders and National Regulatory Authorities (NRAs) must evaluate the adverse drug reactions (ADRs) that occurred and characterize their ...
Short-term prognosis of polypharmacy in elderly patients treated in emergency departments: results from the EDEN project [0.03%]
急诊科老年患者多重用药的短期预后：EDEN项目的发现
Jesus Ruiz Ramos,Aitor Alquézar-Arbé,Ana Juanes Borrego et al.
Jesus Ruiz Ramos et al.
Background: Polypharmacy is a growing phenomenon among elderly individuals. However, there is little information about the frequency of polypharmacy among the elderly population treated in emergency departments (EDs) and ...
Evaluation of early retinal changes in patients on long-term hydroxychloroquine using optical coherence tomography angiography [0.03%]
光学相干断层扫描血管成像评估长期服用羟氯喹患者早期视网膜改变
Huanhuan Zhao,Menglu Pan,Yaping Liu et al.
Huanhuan Zhao et al.
Background: Connective tissue diseases (CTD), including systemic lupus erythematosus and rheumatoid arthritis (RA), have long been treated with hydroxychloroquine (HCQ). However, prolonged HCQ use poses a risk of adverse ...
Direct oral anticoagulant use in hospitalized patients with atrial fibrillation across body mass index categories: design and rationale for a retrospective cohort study [0.03%]
不同体质指数分类的住院房颤患者的直接口服抗凝剂使用情况：一项回顾性队列研究的设计和科学依据
Fahad Shaikh,Rochelle Wynne,Ronald L Castelino et al.
Fahad Shaikh et al.
Background: Atrial fibrillation (AF) and obesity are common conditions globally; yet, there remains suboptimal pharmacological management contributing to high rates of hospitalization in patients with AF. The altered path...
Drug-induced interstitial lung disease: a real-world pharmacovigilance study of the FDA Adverse Event Reporting System from 2004 to 2021 [0.03%]
药物引起的间质性肺疾病：对2004年至2021年FDA不良事件报告系统的真实世界药物流行病学研究
Tingting Jiang,Hui Su,Jing Xu et al.
Tingting Jiang et al.
Background: Drug-induced interstitial lung disease (DILD) is an increasingly common cause of morbidity and mortality. However, due to the lack of specificity, DILD detection remains an unsolved public health challenge. ...
Medication errors by caregivers in the homes of children discharged from a pediatric department in Ghana [0.03%]
加纳一家儿科部门出院儿童家中照看者发生的药物错误
George Tsey Sabblah,Florence van Hunsel,Katja Taxis et al.
George Tsey Sabblah et al.
Background: Medication errors (MEs) by caregivers at home are a cause of morbidity and mortality, shortly after discharge from the hospital. Objectives: ...
Jessica Rose,Nicolas Hulscher,Peter A McCullough
Jessica Rose
Background: Following the roll-out of the Pfizer-BioNTech BNT162b2, Moderna mRNA-1273, and Janssen Ad26.COV2.S coronavirus disease 2019 (COVID-19) injections in the United States, millions of individuals have reported adv...
Association of thrombopoietin-related drugs with thromboembolic events: Mendelian randomization and a real-world study [0.03%]
血小板生成素相关药物与血栓栓塞事件的关联：孟德尔随机化和真实世界研究
Cuilv Liang,Qiying Chen,Yin Zhang
Cuilv Liang
Background: Studies have shown conflicting results when using thrombopoietin-related drugs (TPORD) for thromboembolic events (TEEs). Our study aimed to explore the correlation between TPORDs and TEEs. ...