Safety of belimumab during pregnancy: associations with maternal and fetal or newborn adverse outcomes based on FAERS data [0.03%]
贝利木单抗孕期使用的安全性：基于FAERS数据的母体及胎儿或新生儿不良结局分析
Yujie Lin,Jing Yao
Yujie Lin
Background: Belimumab is a biologic agent used in the treatment of systemic lupus erythematosus (SLE). However, its safety profile during pregnancy has not been fully established, and real-world evidence regarding its ass...
Detection of clinically significant drug-drug interactions in serotonin syndrome: a multisource real-world data and pharmacovigilance study [0.03%]
基于多源真实世界数据和药物警戒的临床显著药物相互作用所致血清素综合征检测研究
Shanshan Xu,Zhihui Song,Dong Wang et al.
Shanshan Xu et al.
Background: Serotonin syndrome (SS) is a potentially life-threatening condition increasingly driven by complex drug-drug interactions (DDIs) as serotonergic agents expand beyond psychiatry into pain management and infecti...
A descriptive, retrospective analysis of the quality of spontaneous adverse event reporting to the Côte d'Ivoire Pharmaceutical and Regulatory Authority and its impact on the causality assessment [0.03%]
描述性回顾分析科特迪瓦药品和监管局自发不良事件报告的质量及其对因果关系评估的影响
Mamadou Kamagaté,Viviane Jusot,Diaby Mory et al.
Mamadou Kamagaté et al.
Background: In Côte d'Ivoire, pharmacovigilance is not a routine activity in most healthcare facilities and many healthcare professionals have limited knowledge of pharmacovigilance methods. ...
Absence of pharmacovigilance signals for bleeding events associated with warfarin-SSRI drug interactions: a comparative analysis of FAERS and CVARD databases [0.03%]
未发现华法林-选择性5-羟色胺再摄取抑制剂相互作用导致出血事件的药物警戒信号：来自FAERS和CVARDS数据库的比较分析
Pan Zhang,Siyuan Cheng,Junlin Diao et al.
Pan Zhang et al.
Background: Warfarin and selective serotonin reuptake inhibitors (SSRIs) are frequently co-prescribed in clinical practice, particularly among elderly patients with comorbid cardiovascular and psychiatric conditions. Alth...
Comparison of pharmacovigilance and mechanism analysis of the vascular toxicity caused by platin-based chemotherapy: integration of FAERS analysis, network pharmacology, and endothelial validation [0.03%]
基于FAERS分析、网络药理学和内皮细胞验证的血管毒性用药安全性评价及机制研究：以铂类化疗药物为例
Yuzhu Chen,Chunhua Wang,Peng Jiang et al.
Yuzhu Chen et al.
Background: Understanding of the possible vasoactive toxicities associated with platinum‑containing chemotherapeutic drugs for solid tumors remains limited. ...
Pharmacogenetic variants in pharmacokinetic and pharmacodynamic pathways and clinical factors associated with bleeding risk in Thai patients receiving rivaroxaban: a case-control study [0.03%]
泰国接受利伐沙班患者出血风险相关的药理基因组学变异和临床因素：一项病例对照研究
Varalee Yodsurang,Krit Wattanathum,Thanate Srimatimanon et al.
Varalee Yodsurang et al.
Background: While bleeding is an inherent risk of all anticoagulant therapies, individual susceptibility varies considerably. Rivaroxaban, a direct oral anticoagulant widely used for thromboembolic prevention, is associat...
Adverse events associated with statin co-use in breast cancer patients: a disproportionality analysis based on the FDA Adverse Event Reporting System [0.03%]
基于美国食品药品监督管理局不良事件报告系统的统计分析：乳腺癌患者的不良事件
Yunnan Zhang,Wenxing Peng,Wei Yang et al.
Yunnan Zhang et al.
Background: An increasing number of breast cancer patients are using statins concomitantly. However, there are relatively few safety studies on the association between statins and adverse events (AEs) during breast cancer...
Medication-related nephrotic syndrome: a real-world study from 2004 to 2024 based on the Food and Drug Administration Adverse Event Reporting System [0.03%]
基于食品药品监督管理局不良事件报告系统的2004-2024年真实世界研究：药物相关的肾病综合征
Yan Zheng,Tingfen Han,Yanjun Wu et al.
Yan Zheng et al.
Background: Nephrotic syndrome is a clinical syndrome caused by glomerular injury. Medication-related nephrotic syndrome (MRNS) has become an important focus of pharmacovigilance. However, there is currently a lack of rea...
Metabolic and nutritional stress-associated dilated cardiomyopathy in the setting of semaglutide use and long-term nicotine replacement therapy: a case report and literature review [0.03%]
关于使用司美格鲁肽和长期尼古丁替代疗法背景下与代谢及营养压力相关的扩张型心肌病的病例报告和文献综述
Siddarth Sriram,Leonard Arnolda
Siddarth Sriram
Dilated cardiomyopathy (DCM) is a leading cause of heart failure and cardiac transplantation worldwide. It is a multifactorial condition with diverse aetiologies, in which metabolic and nutritional factors are increasingly recognised, where...
Adverse drug reactions associated with glycyrrhiza-containing Chinese patent medicines: a literature-based analysis of individual case reports and clinical trials [0.03%]
含甘草类中成药的不良反应事件及临床试验报告分析
Ziyi Yu,Danwei Wu,Yitong Xie et al.
Ziyi Yu et al.
Background: Licorice, a commonly used traditional Chinese medicine in clinical practice, and pharmaceuticals with glycyrrhiza or glycyrrhiza extract as the main component play an important role in the treatment of hepatic...