An Endocrine Perspective of Nonalcoholic Fatty Liver Disease (NAFLD) [0.03%]
从内分泌学角度看非酒精性脂肪肝疾病（NAFLD）
Romina Lomonaco,Janet Chen,Kenneth Cusi
Romina Lomonaco
Endocrinologists are encountering patients with obesity-related complications such as metabolic syndrome (MetS) and type 2 diabetes mellitus (T2DM) on a daily basis. Nonalcoholic fatty liver disease (NAFLD) is a liver condition characterize...
The prospect of induced pluripotent stem cells for diabetes mellitus treatment [0.03%]
诱导多能干细胞治疗糖尿病的前景
Andreas Soejitno,Pande Kadek Aditya Prayudi
Andreas Soejitno
A continuous search for a permanent cure for diabetes mellitus is underway with several remarkable discoveries over the past few decades. One of these is the potential of pancreatic stem/progenitor cells to rejuvenate functional β cells. H...
David A Liebner,Manisha H Shah
David A Liebner
Therapeutic options for advanced, unresectable radioiodine-resistant thyroid cancers have historically been limited. Recent progress in understanding the pathogenesis of the various subtypes of thyroid cancer has led to increased interest i...
Adverse orthopedic effect of exogenous estrogens on men undergoing cross-gender hormonal therapy [0.03%]
跨性别激素治疗男性的外源性雌激素对骨骼的不良影响
Muhammad Adil Abbas Khan,Zain A Sobani,Mark Gorman
Muhammad Adil Abbas Khan
Effect of genetic polymorphisms on the development of secondary failure to sulfonylurea in egyptian patients with type 2 diabetes [0.03%]
基因多态性对埃及2型糖尿病患者磺脲类继发失效影响的研究
Alaa E El-Sisi,Sahar K Hegazy,Shereen S Metwally et al.
Alaa E El-Sisi et al.
Objective: This study investigated the possibility that genetic factors, such as polymorphism of K inward rectifier subunit (Kir6.2), E23K, and Arg(972) polymorphism of insulin receptor sub-strate-1 (IRS-1), may predispos...
Dedicated to evidence-based medicine and the evaluation of new therapeutic approaches in the field [0.03%]
致力于循证医学及该领域新治疗方法的评价
Christoph Schindler
Christoph Schindler
Christian M Girgis,Bernard L Champion,Jack R Wall
Christian M Girgis
Graves' disease is the most common cause of hyperthyroidism in the developed world. It is caused by an immune defect in genetically susceptible individuals in whom the production of unique antibodies results in thyroid hormone excess and gl...
Sapropterin hydrochloride: enzyme enhancement therapy for phenylketonuria [0.03%]
盐酸 sapropterin：苯酮尿症的酶增强疗法
Robin Lachmann
Robin Lachmann
Phenylketonuria (PKU) is an inherited disorder of amino acid metabolism caused by deficiency of the enzyme phenylalanine hydroxylase (PAH). Historically PKU was a common genetic cause of severe learning difficulties and developmental delay,...
Shashithej K Narayana,David R Woods,Christopher J Boos
Shashithej K Narayana
Amiodarone is a highly effective and well-established antiarrrhythmic drug. It can be used to treat supraventricular and ventricular tachyarrhythmias and has the added advantage of being well tolerated in patients with impaired left ventric...